Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast

por Reijns, Martin A M, Auchynnikava, Tatsiana, Beggs, Jean D
Publicado 2009

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA

por Spiller, Michael P., Boon, Kum-Loong, Reijns, Martin A. M., Beggs, Jean D.
Publicado 2007

Lagging strand replication shapes the mutational landscape of the genome

por Reijns, Martin A. M., Kemp, Harriet, Ding, James, de Procé, Sophie Marion, Jackson, Andrew P., Taylor, Martin S.
Publicado 2015

PCNA directs type 2 RNase H activity on DNA replication and repair substrates

por Bubeck, Doryen, Reijns, Martin A. M., Graham, Stephen C., Astell, Katy R., Jones, E. Yvonne, Jackson, Andrew P.
Publicado 2011

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

por Reijns, Martin A. M., Bubeck, Doryen, Gibson, Lucien C. D., Graham, Stephen C., Baillie, George S., Jones, E. Yvonne, Jackson, Andrew P.
Publicado 2011

User acceptability of saliva and gargle samples for identifying COVID-19 positive high-risk workers and household contacts

por McLennan, Kirsty, Barton, Ellen, Lang, Christie, Adams, Ian R., McAllister, Gina, Reijns, Martin A.M., Templeton, Kate, Johannessen, Ingólfur, Leckie, Alastair, Gilbert, Nick
Publicado 2022

Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity

por Vaisman, Alexandra, Łazowski, Krystian, Reijns, Martin A. M., Walsh, Erin, McDonald, John P., Moreno, Kristiniana C., Quiros, Dominic R., Schmidt, Marlen, Kranz, Harald, Yang, Wei, Makiela‐Dzbenska, Karolina, Woodgate, Roger
Publicado 2021

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

por Rigby, Rachel E, Webb, Lauren M, Mackenzie, Karen J, Li, Yue, Leitch, Andrea, Reijns, Martin A M, Lundie, Rachel J, Revuelta, Ailsa, Davidson, Donald J, Diebold, Sandra, Modis, Yorgo, MacDonald, Andrew S, Jackson, Andrew P
Publicado 2014

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

por Moss, Chloe F., Dalla Rosa, Ilaria, Hunt, Lilian E., Yasukawa, Takehiro, Young, Robert, Jones, Aleck W. E., Reddy, Kaalak, Desai, Radha, Virtue, Sam, Elgar, Greg, Voshol, Peter, Taylor, Martin S., Holt, Ian J., Reijns, Martin A. M., Spinazzola, Antonella
Publicado 2017

cGAS surveillance of micronuclei links genome instability to innate immunity

por Mackenzie, Karen J., Carroll, Paula, Martin, Carol-Anne, Murina, Olga, Fluteau, Adeline, Simpson, Daniel, Olova, Nelly, Sutcliffe, Hannah, Rainger, Jacqueline, Robertson, Andrea, Osborn, Ruby, Wheeler, Ann, Nowotny, Marcin, Gilbert, Nick, Chandra, Tamir, Reijns, Martin A. M., Jackson, Andrew P.
Publicado 2017

Biallelic variants in DNA2 cause microcephalic primordial dwarfism

por Tarnauskaitė, Žygimantė, Bicknell, Louise S., Marsh, Joseph A., Murray, Jennie E., Parry, David A., Logan, Clare V., Bober, Michael B., de Silva, Deepthi C., Duker, Angela L., Sillence, David, Wise, Carol, Jackson, Andrew P., Murina, Olga, Reijns, Martin A. M.
Publicado 2019

PRIM1 deficiency causes a distinctive primordial dwarfism syndrome

por Parry, David A., Tamayo-Orrego, Lukas, Carroll, Paula, Marsh, Joseph A., Greene, Philip, Murina, Olga, Uggenti, Carolina, Leitch, Andrea, Káposzta, Rita, Merő, Gabriella, Nagy, Andrea, Orlik, Brigitta, Kovács-Pászthy, Balázs, Quigley, Alan J., Riszter, Magdolna, Rankin, Julia, Reijns, Martin A.M., Szakszon, Katalin, Jackson, Andrew P.
Publicado 2020

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

por Reijns, Martin A.M., Rabe, Björn, Rigby, Rachel E., Mill, Pleasantine, Astell, Katy R., Lettice, Laura A., Boyle, Shelagh, Leitch, Andrea, Keighren, Margaret, Kilanowski, Fiona, Devenney, Paul S., Sexton, David, Grimes, Graeme, Holt, Ian J., Hill, Robert E., Taylor, Martin S., Lawson, Kirstie A., Dorin, Julia R., Jackson, Andrew P.
Publicado 2012

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

por Reijns, Martin A. M., Parry, David A., Williams, Thomas C., Nadeu, Ferran, Hindshaw, Rebecca L., Rios Szwed, Diana O., Nicholson, Michael D., Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J., Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S., Jackson, Andrew P.
Publicado 2022

Publisher Correction: Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

por Reijns, Martin A. M., Parry, David A., Williams, Thomas C., Nadeu, Ferran, Hindshaw, Rebecca L., Rios Szwed, Diana O., Nicholson, Michael D., Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J., Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S., Jackson, Andrew P.
Publicado 2022

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

por Zimmermann, Michal, Murina, Olga, Reijns, Martin A. M., Agathanggelou, Angelo, Challis, Rachel, Tarnauskaitė, Žygimantė, Muir, Morwenna, Fluteau, Adeline, Aregger, Michael, McEwan, Andrea, Yuan, Wei, Clarke, Matthew, Lambros, Maryou B., Paneesha, Shankara, Moss, Paul, Chandrashekhar, Megha, Angers, Stephane, Moffat, Jason, Brunton, Valerie G., Hart, Traver, de Bono, Johann, Stankovic, Tatjana, Jackson, Andrew P., Durocher, Daniel
Publicado 2018

Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

por Heyn, Patricia, Logan, Clare V., Fluteau, Adeline, Challis, Rachel C., Auchynnikava, Tatsiana, Martin, Carol-Anne, Marsh, Joseph A., Taglini, Francesca, Kilanowski, Fiona, Parry, David A., Cormier-Daire, Valerie, Fong, Chin-To, Gibson, Kate, Hwa, Vivian, Ibáñez, Lourdes, Robertson, Stephen P., Sebastiani, Giorgia, Rappsilber, Juri, Allshire, Robin C., Reijns, Martin A.M., Dauber, Andrew, Sproul, Duncan, Jackson, Andrew P.
Publicado 2018

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

por Giordano, Anna Maria Sole, Luciani, Marco, Gatto, Francesca, Abou Alezz, Monah, Beghè, Chiara, Della Volpe, Lucrezia, Migliara, Alessandro, Valsoni, Sara, Genua, Marco, Dzieciatkowska, Monika, Frati, Giacomo, Tahraoui-Bories, Julie, Giliani, Silvia Clara, Orcesi, Simona, Fazzi, Elisa, Ostuni, Renato, D’Alessandro, Angelo, Di Micco, Raffaella, Merelli, Ivan, Lombardo, Angelo, Reijns, Martin A.M., Gromak, Natalia, Gritti, Angela, Kajaste-Rudnitski, Anna
Publicado 2022

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

por Aden, Konrad, Bartsch, Kareen, Dahl, Joseph, Reijns, Martin A.M., Esser, Daniela, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Wottawa, Felix, Ito, Go, Mishra, Neha, Knittler, Katharina, Burkholder, Adam, Welz, Lina, van Es, Johan, Tran, Florian, Lipinski, Simone, Kakavand, Nassim, Boeger, Christine, Lucius, Ralph, von Schoenfels, Witigo, Schafmayer, Clemens, Lenk, Lennart, Chalaris, Athena, Clevers, Hans, Röcken, Christoph, Kaleta, Christoph, Rose-John, Stefan, Schreiber, Stefan, Kunkel, Thomas, Rabe, Björn, Rosenstiel, Philip
Publicado 2019

TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism

por Harley, Margaret E., Murina, Olga, Leitch, Andrea, Higgs, Martin R., Bicknell, Louise S., Yigit, Gökhan, Blackford, Andrew N., Zlatanou, Anastasia, Mackenzie, Karen J., Reddy, Kaalak, Halachev, Mihail, McGlasson, Sarah, Reijns, Martin A. M., Fluteau, Adeline, Martin, Carol-Anne, Sabbioneda, Simone, Elcioglu, Nursel H., Altmüller, Janine, Thiele, Holger, Greenhalgh, Lynn, Chessa, Luciana, Maghnie, Mohamad, Salim, Mahmoud, Bober, Michael B., Nürnberg, Peter, Jackson, Stephen P., Hurles, Matthew E., Wollnik, Bernd, Stewart, Grant S., Jackson, Andrew P.
Publicado 2015