Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells

por Reis-Mendes, Ana, Alves, Marisa, Carvalho, Félix, Remião, Fernando, Bastos, Maria Lourdes, Costa, Vera Marisa
Publicado 2018

The Metabolic Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases

por Brandão, Sofia Reis, Reis-Mendes, Ana, Neuparth, Maria João, Carvalho, Félix, Ferreira, Rita, Costa, Vera Marisa
Publicado 2023

The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells

por Reis-Mendes, Ana, Carvalho, Félix, Remião, Fernando, Sousa, Emília, Bastos, Maria de Lourdes, Costa, Vera Marisa
Publicado 2019

Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells

por Pereira-Oliveira, Maria, Reis-Mendes, Ana, Carvalho, Félix, Remião, Fernando, Bastos, Maria de Lourdes, Costa, Vera Marisa
Publicado 2019

Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice

por Brandão, Sofia Reis, Reis-Mendes, Ana, Duarte-Araújo, Margarida, Neuparth, Maria João, Rocha, Hugo, Carvalho, Félix, Ferreira, Rita, Costa, Vera Marisa
Publicado 2023

The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice

por Reis-Mendes, Ana, Ferreira, Mariana, Duarte, José Alberto, Duarte-Araújo, Margarida, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Publicado 2023

Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice

por Reis-Mendes, Ana, Padrão, Ana Isabel, Duarte, José Alberto, Gonçalves-Monteiro, Salomé, Duarte-Araújo, Margarida, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Publicado 2021

A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study

por Dias-Carvalho, Ana, Margarida-Araújo, Ana, Reis-Mendes, Ana, Sequeira, Catarina Oliveira, Pereira, Sofia Azeredo, Guedes de Pinho, Paula, Carvalho, Félix, Sá, Susana Isabel, Fernandes, Eduarda, Costa, Vera Marisa
Publicado 2023

Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice

por Reis-Mendes, Ana, Dores-Sousa, José Luís, Padrão, Ana Isabel, Duarte-Araújo, Margarida, Duarte, José Alberto, Seabra, Vítor, Gonçalves-Monteiro, Salomé, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Publicado 2021