Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine

por Zhu, Zhou, Ihle, Nathan T., Rejto, Paul A., Zarrinkar, Patrick P.
Publicado 2016

Statistical method on nonrandom clustering with application to somatic mutations in cancer

por Ye, Jingjing, Pavlicek, Adam, Lunney, Elizabeth A, Rejto, Paul A, Teng, Chi-Hse
Publicado 2010

Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression

por Xie, Tao, Musteanu, Monica, Lopez-Casas, Pedro P., Shields, David J., Olson, Peter, Rejto, Paul A., Hidalgo, Manuel
Publicado 2015

TNER: a novel background error suppression method for mutation detection in circulating tumor DNA

por Deng, Shibing, Lira, Maruja, Huang, Donghui, Wang, Kai, Valdez, Crystal, Kinong, Jennifer, Rejto, Paul A., Bienkowska, Jadwiga, Hardwick, James, Xie, Tao
Publicado 2018

Dose-dependent effects of small-molecule antagonists on the genomic landscape of androgen receptor binding

por Zhu, Zhou, Shi, Manli, Hu, Wenyue, Estrella, Heather, Engebretsen, Jon, Nichols, Tim, Briere, David, Hosea, Natilie, Los, Gerrit, Rejto, Paul A, Fanjul, Andrea
Publicado 2012

A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

por Lee, Nathan V., Lira, Maruja E., Pavlicek, Adam, Ye, Jingjing, Buckman, Dana, Bagrodia, Shubha, Srinivasa, Sreesha P., Zhao, Yongjun, Aparicio, Samuel, Rejto, Paul A., Christensen, James G., Ching, Keith A.
Publicado 2012

Correction: A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

por Lee, Nathan V., Lira, Maruja E., Pavlicek, Adam, Ye, Jingjing, Buckman, Dana, Bagrodia, Shubha, Srinivasa, Sreesha P., Zhao, Yongjun, Aparicio, Samuel, Rejto, Paul A., Christensen, James G., Ching, Keith A.
Publicado 2012

Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors

por Zhong, Wenyan, Myers, Jeremy S., Wang, Fang, Wang, Kai, Lucas, Justin, Rosfjord, Edward, Lucas, Judy, Hooper, Andrea T., Yang, Sharon, Lemon, Lu Anna, Guffroy, Magali, May, Chad, Bienkowska, Jadwiga R., Rejto, Paul A.
Publicado 2020

Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease

por Belmont, Peter J., Budinska, Eva, Jiang, Ping, Sinnamon, Mark J., Coffee, Erin, Roper, Jatin, Xie, Tao, Rejto, Paul A., Derkits, Sahra, Sansom, Owen J., Delorenzi, Mauro, Tejpar, Sabine, Hung, Kenneth E., Martin, Eric S.
Publicado 2014

A Comprehensive Characterization of Genome-Wide Copy Number Aberrations in Colorectal Cancer Reveals Novel Oncogenes and Patterns of Alterations

por Xie, Tao, d’ Ario, Giovanni, Lamb, John R., Martin, Eric, Wang, Kai, Tejpar, Sabine, Delorenzi, Mauro, Bosman, Fred T., Roth, Arnaud D., Yan, Pu, Bougel, Stephanie, Di Narzo, Antonio Fabio, Popovici, Vlad, Budinská, Eva, Mao, Mao, Weinrich, Scott L., Rejto, Paul A., Hodgson, J. Graeme
Publicado 2012

Preclinical Evaluation of (89)Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy

por Maresca, Kevin P., Chen, Jianqing, Mathur, Divya, Giddabasappa, Anand, Root, Adam, Narula, Jatin, King, Lindsay, Schaer, David, Golas, Jonathan, Kobylarz, Keith, Rosfjord, Edward, Keliher, Edmund, Chen, Laigao, Ram, Sripad, Pickering, Eve H., Hardwick, James S., Rejto, Paul A., Hussein, Amira, Ilovich, Ohad, Staton, Kevin, Wilson, Ian, McCarthy, Timothy J.
Publicado 2021

Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib

por Zhu, Zhou, Turner, Nicholas C., Loi, Sherene, André, Fabrice, Martin, Miguel, Diéras, Véronique, Gelmon, Karen A., Harbeck, Nadia, Zhang, Cathy, Cao, Joan Q., Yan, Zhengming, Lu, Dongrui R., Wei, Ping, VanArsdale, Todd L., Rejto, Paul A., Huang, Xin, Rugo, Hope S., Loibl, Sibylle, Cristofanilli, Massimo, Finn, Richard S., Liu, Yuan
Publicado 2022

Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome

por Park, Yeon Hee, Lal, Samir, Lee, Jeong Eon, Choi, Yoon-La, Wen, Ji, Ram, Sripad, Ding, Ying, Lee, Soo-Hyeon, Powell, Eric, Lee, Se Kyung, Yu, Jong Han, Ching, Keith A., Nam, Jae-Yong, Kim, Seok Won, Nam, Seok Jin, Kim, Ji-Yeon, Cho, Soo Youn, Park, Seri, Kim, Jinho, Hwang, Soohyn, Kim, Yu Jin, Bonato, Vinicius, Fernandez, Diane, Deng, Shibing, Wang, Shuoguo, Shin, Hyuntae, Kang, Eun-Suk, Park, Woong-Yang, Rejto, Paul A., Bienkowska, Jadwiga, Kan, Zhengyan
Publicado 2020

Longitudinal multi-omics study of palbociclib resistance in HR-positive/HER2-negative metastatic breast cancer

por Park, Yeon Hee, Im, Seock-Ah, Park, Kyunghee, Wen, Ji, Lee, Kyung-Hun, Choi, Yoon-La, Lee, Won-Chul, Min, Ahrum, Bonato, Vinicius, Park, Seri, Ram, Sripad, Lee, Dae-Won, Kim, Ji-Yeon, Lee, Su Kyeong, Lee, Won-Woo, Lee, Jisook, Kim, Miso, Kim, Hyun Seon, Weinrich, Scott L., Ryu, Han Suk, Kim, Tae Yong, Dann, Stephen, Kim, Yu-Jin, Fernandez, Diane R., Koh, Jiwon, Wang, Shuoguo, Park, Song Yi, Deng, Shibing, Powell, Eric, Ravi, Rupesh Kanchi, Bienkowska, Jadwiga, Rejto, Paul A., Park, Woong-Yang, Kan, Zhengyan
Publicado 2023

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

por Kan, Zhengyan, Zheng, Hancheng, Liu, Xiao, Li, Shuyu, Barber, Thomas D., Gong, Zhuolin, Gao, Huan, Hao, Ke, Willard, Melinda D., Xu, Jiangchun, Hauptschein, Robert, Rejto, Paul A., Fernandez, Julio, Wang, Guan, Zhang, Qinghui, Wang, Bo, Chen, Ronghua, Wang, Jian, Lee, Nikki P., Zhou, Wei, Lin, Zhao, Peng, Zhiyu, Yi, Kang, Chen, Shengpei, Li, Lin, Fan, Xiaomei, Yang, Jie, Ye, Rui, Ju, Jia, Wang, Kai, Estrella, Heather, Deng, Shibing, Wei, Ping, Qiu, Ming, Wulur, Isabella H., Liu, Jiangang, Ehsani, Mariam E., Zhang, Chunsheng, Loboda, Andrey, Sung, Wing Kin, Aggarwal, Amit, Poon, Ronnie T., Fan, Sheung Tat, Wang, Jun, Hardwick, James, Reinhard, Christoph, Dai, Hongyue, Li, Yingrui, Luk, John M., Mao, Mao
Publicado 2013