Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors FcεRI and FcγRIII

por Rathod, Sanjay, Ramsey, Manda, Relling, Mary V., Finkelman, Fred D., Fernandez, Christian A.
Publicado 2019

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells

por Panetta, John C., Sparreboom, Alex, Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Publicado 2010

A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required

por Dering, Carmen, König, Inke R., Ramsey, Laura B., Relling, Mary V., Yang, Wenjian, Ziegler, Andreas
Publicado 2014

Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia

por Rühs, Hauke, Becker, Achim, Drescher, Anne, Panetta, John C., Pui, Ching-Hon, Relling, Mary V., Jaehde, Ulrich
Publicado 2012

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice

por Finch, Emily R., Payton, Monique A., Jenkins, David A., Cai, Xiangjun, Li, Lie, Karol, Seth E., Relling, Mary V., Janke, Laura J.
Publicado 2020

FUNCTIONAL CHARACTERIZATION OF ABCC2 PROMOTER POLYMORPHISMS AND ALLELE SPECIFIC EXPRESSION

por Nguyen, Tan D., Markova, Svetlana, Liu, Wanqing, Gow, Jason M., Baldwin, R. Michael, Habashian, Mahnoush, Relling, Mary V., Ratain, Mark J., Kroetz, Deanna L.
Publicado 2012

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

por Liu, Chengcheng, Janke, Laura J., Kawedia, Jitesh D., Ramsey, Laura B., Cai, Xiangjun, Mattano, Leonard A., Boyd, Kelli L., Funk, Amy J., Relling, Mary V.
Publicado 2016

Concordant Gene Expression in Leukemia Cells and Normal Leukocytes Is Associated with Germline cis-SNPs

por French, Deborah, Yang, Wenjian, Hamilton, Leo H., Neale, Geoffrey, Fan, Yiping, Downing, James R., Cox, Nancy J., Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2008

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

por Karol, Seth E., Janke, Laura J., Panetta, John C., Ramsey, Laura B., Cai, Xiangjun, Payton, Monique A., Jenkins, David A., Evans, William E., Relling, Mary V.
Publicado 2019

In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile

por Sorich, Michael J, Pottier, Nicolas, Pei, Deqing, Yang, Wenjian, Kager, Leo, Stocco, Gabriele, Cheng, Cheng, Panetta, John C, Pui, Ching-Hon, Relling, Mary V, Cheok, Meyling H, Evans, William E
Publicado 2008

Concordance between glucose-6-phosphate dehydrogenase (G6PD) genotype and phenotype and rasburicase use in patients with hematologic malignancies

por Robinson, Katherine M., Yang, Wenjian, Haidar, Cyrine E., Hankins, Jane S., Jay, Dennis W., Kornegay, Nancy, Rubnitz, Jeffrey E., Broeckel, Ulrich, Cheng, Cheng, Pui, Ching-Hon, Jeha, Sima, Relling, Mary V.
Publicado 2018

Genetic Studies of a Cluster of Acute Lymphoblastic Leukemia Cases in Churchill County, Nevada

por Steinberg, Karen K., Relling, Mary V., Gallagher, Margaret L., Greene, Christopher N., Rubin, Carol S., French, Deborah, Holmes, Adrianne K., Carroll, William L., Koontz, Deborah A., Sampson, Eric J., Satten, Glen A.
Publicado 2007

Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Gr...

por Caudle, Kelly E., Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Swen, Jesse J., Haidar, Cyrine E., Klein, Teri E., Gammal, Roseann S., Relling, Mary V., Scott, Stuart A., Hertz, Daniel L., Guchelaar, Henk‐Jan, Gaedigk, Andrea
Publicado 2019

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

por Ramsey, Laura B., Janke, Laura J., Payton, Monique A., Cai, Xiangjun, Paugh, Steven W., Karol, Seth E., Kamdem, Landry Kamdem, Cheng, Cheng, Williams, Richard T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2015

Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC)

por Caudle, Kelly E., Dunnenberger, Henry M., Freimuth, Robert R., Peterson, Josh F., Burlison, Jonathan D., Whirl-Carrillo, Michelle, Scott, Stuart A., Rehm, Heidi L., Williams, Marc S., Klein, Teri E., Relling, Mary V., Hoffman, James M.
Publicado 2017

Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments

por Pauley, Jennifer L., Panetta, John C., Crews, Kristine R., Pei, Deqing, Cheng, Cheng, McCormick, John, Howard, Scott C., Sandlund, John T., Jeha, Sima, Ribeiro, Raul, Rubnitz, Jeffrey, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2013

Erratum to: Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments

por Pauley, Jennifer L., Panetta, John C., Crews, Kristine R., Pei, Deqing, Cheng, Cheng, McCormick, John, Howard, Scott C., Sandlund, John T., Jeha, Sima, Ribeiro, Raul, Rubnitz, Jeffrey, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2013

Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia

por Yang, Wenjian, Karol, Seth E., Hoshitsuki, Keito, Lee, Shawn, Larsen, Eric C., Winick, Naomi, Carroll, William L., Loh, Mignon L., Raetz, Elizabeth A., Hunger, Stephen P., Winter, Stuart S., Dunsmore, Kimberly P., Devidas, Meenakshi, Relling, Mary V., Yang, Jun J.
Publicado 2022

Development and use of active clinical decision support for preemptive pharmacogenomics

por Bell, Gillian C, Crews, Kristine R, Wilkinson, Mark R, Haidar, Cyrine E, Hicks, J Kevin, Baker, Donald K, Kornegay, Nancy M, Yang, Wenjian, Cross, Shane J, Howard, Scott C, Freimuth, Robert R, Evans, William E, Broeckel, Ulrich, Relling, Mary V, Hoffman, James M
Publicado 2014

Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing

por Matreyek, Kenneth A., Starita, Lea M., Stephany, Jason J., Martin, Beth, Chiasson, Melissa A., Gray, Vanessa E., Kircher, Martin, Khechaduri, Arineh, Dines, Jennifer N., Hause, Ronald J., Bhatia, Smita, Evans, William E., Relling, Mary V., Yang, Wenjian, Shendure, Jay, Fowler, Douglas M.
Publicado 2018