Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches

por Carabet, Lavinia A., Rennie, Paul S., Cherkasov, Artem
Publicado 2018

Targeting Alternative Sites on the Androgen Receptor to Treat Castration-Resistant Prostate Cancer

por Lallous, Nada, Dalal, Kush, Cherkasov, Artem, Rennie, Paul S.
Publicado 2013

Computer-Aided Ligand Discovery for Estrogen Receptor Alpha

por Bafna, Divya, Ban, Fuqiang, Rennie, Paul S., Singh, Kriti, Cherkasov, Artem
Publicado 2020

To Die or to Survive, a Fatal Question for the Destiny of Prostate Cancer Cells after Androgen Deprivation Therapy

por Zhang, Kai-Xin, Firus, Jessica, Prieur, Brenda, Jia, William, Rennie, Paul S.
Publicado 2011

AR-v7 protein expression is regulated by protein kinase and phosphatase

por Li, Yinan, Xie, Ning, Gleave, Martin E., Rennie, Paul S., Dong, Xuesen
Publicado 2015

Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection

por Rennie, Paul, Bowtell, Philip, Hull, David, Charbonneau, Duane, Lambkin-Williams, Robert, Oxford, John
Publicado 2007

Computer-Aided Discovery of Small Molecule Inhibitors of Transcriptional Activity of TLX (NR2E1) Nuclear Receptor

por Dueva, Evgenia, Singh, Kriti, Kalyta, Anastasia, LeBlanc, Eric, Rennie, Paul S., Cherkasov, Artem
Publicado 2018

Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

por Margiotti, Katia, Wafa, Latif A, Cheng, Helen, Novelli, Giuseppe, Nelson, Colleen C, Rennie, Paul S
Publicado 2007

Tumour-specific triple-regulated oncolytic herpes virus to target glioma

por Delwar, Zahid M., Liu, Guoyu, Kuo, Yvonne, Lee, Cleo, Bu, Luke, Rennie, Paul S., Jia, William W.
Publicado 2016

Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer

por Carabet, Lavinia A., Leblanc, Eric, Lallous, Nada, Morin, Helene, Ghaidi, Fariba, Lee, Joseph, Rennie, Paul S., Cherkasov, Artem
Publicado 2019

Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor

por Radaeva, Mariia, Ban, Fuqiang, Zhang, Fan, LeBlanc, Eric, Lallous, Nada, Rennie, Paul S., Gleave, Martin E., Cherkasov, Artem
Publicado 2021

TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis

por Khatamianfar, Vida, Valiyeva, Fatma, Rennie, Paul S, Lu, Wei-yang, Yang, Burton B, Bauman, Glenn S, Moussa, Madeleine, Xuan, Jim W
Publicado 2012

Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers

por Singh, Kriti, Munuganti, Ravi S. N., Lallous, Nada, Dalal, Kush, Yoon, Ji Soo, Sharma, Aishwariya, Yamazaki, Takeshi, Cherkasov, Artem, Rennie, Paul S.
Publicado 2018

In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α

por Singh, Kriti, Munuganti, Ravi Shashi Nayana, Leblanc, Eric, Lin, Yu Lun, Leung, Euphemia, Lallous, Nada, Butler, Miriam, Cherkasov, Artem, Rennie, Paul S
Publicado 2015

Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer

por Barfeld, Stefan J., Fazli, Ladan, Persson, Margareta, Marjavaara, Lisette, Urbanucci, Alfonso, Kaukoniemi, Kirsi M., Rennie, Paul S., Ceder, Yvonne, Chabes, Andrei, Visakorpi, Tapio, Mills, Ian G.
Publicado 2015

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks

por Barfeld, Stefan J., Urbanucci, Alfonso, Itkonen, Harri M., Fazli, Ladan, Hicks, Jessica L., Thiede, Bernd, Rennie, Paul S., Yegnasubramanian, Srinivasan, DeMarzo, Angelo M., Mills, Ian G.
Publicado 2017

20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors

por Ben-Eltriki, Mohamed, Deb, Subrata, Hassona, Mohamed, Meckling, Gray, Fazli, Ladan, Chin, Mei Yieng, Lallous, Nada, Yamazaki, Takeshi, Jia, William, Rennie, Paul S., Cherkasov, Artem, Tomlinson Guns, Emma S.
Publicado 2018

Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors

por Radaeva, Mariia, Li, Huifang, LeBlanc, Eric, Dalal, Kush, Ban, Fuqiang, Ciesielski, Fabrice, Chow, Bonny, Morin, Helene, Awrey, Shannon, Singh, Kriti, Rennie, Paul S., Lallous, Nada, Cherkasov, Artem
Publicado 2022

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment

por Hosseini-Beheshti, Elham, Choi, Wendy, Weiswald, Louis-Bastien, Kharmate, Geetanjali, Ghaffari, Mazyar, Roshan-Moniri, Mani, Hassona, Mohamed D., Chan, Leslie, Chin, Mei Yieng, Tai, Isabella T., Rennie, Paul S., Fazli, Ladan, Guns, Emma S. Tomlinson
Publicado 2016

Divergent androgen regulation of unfolded protein response pathways drives prostate cancer

por Sheng, Xia, Arnoldussen, Yke Jildouw, Storm, Margrethe, Tesikova, Martina, Nenseth, Hatice Zeynep, Zhao, Sen, Fazli, Ladan, Rennie, Paul, Risberg, Bjørn, Wæhre, Håkon, Danielsen, Håvard, Mills, Ian G, Jin, Yang, Hotamisligil, Gökhan, Saatcioglu, Fahri
Publicado 2015