Successes and Challenges in Phenotype-Based Lead Discovery for Prion Diseases: Miniperspective

por Ghaemmaghami, Sina, Russo, Miranda, Renslo, Adam R.
Publicado 2014

Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron

por Chen, Jun, Gonciarz, Ryan L., Renslo, Adam R.
Publicado 2021

Correction: Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron

por Chen, Jun, Gonciarz, Ryan L., Renslo, Adam R.
Publicado 2021

Predicting Binding to P-Glycoprotein by Flexible Receptor Docking

por Dolghih, Elena, Bryant, Clifford, Renslo, Adam R., Jacobson, Matthew P.
Publicado 2011

Efficient and Stereocontrolled Synthesis of 1,2,4-Trioxolanes Useful for Ferrous Iron-Dependent Drug Delivery

por Fontaine, Shaun D., DiPasquale, Antonio G., Renslo, Adam R.
Publicado 2014

Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials

por Blank, Brian R., Gut, Jiri, Rosenthal, Philip J., Renslo, Adam R.
Publicado 2023

Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane

por Blank, Brian R., Gut, Jiri, Rosenthal, Philip J., Renslo, Adam R.
Publicado 2017

Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System

por Osorio, Yaneth, Travi, Bruno L., Renslo, Adam R., Peniche, Alex G., Melby, Peter C.
Publicado 2011

Protein and Chemical Determinants of BL-1249 Action and Selectivity for K(2P) Channels

por Pope, Lianne, Arrigoni, Cristina, Lou, Hubing, Bryant, Clifford, Gallardo-Godoy, Alejandra, Renslo, Adam R., Minor, Daniel L.
Publicado 2018

Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome

por Griffin, Aliesha L, Jaishankar, Priyadarshini, Grandjean, Jean-Marc, Olson, Steven H, Renslo, Adam R, Baraban, Scott C
Publicado 2019

A Fragmenting Hybrid Approach for Targeted Delivery of Multiple Therapeutic Agents to the Malaria Parasite

por Mahajan, Sumit S, Deu, Edgar, Lauterwasser, Erica M W, Leyva, Melissa J, Ellman, Jonathan A, Bogyo, Matthew, Renslo, Adam R
Publicado 2011

Broad-Spectrum Allosteric Inhibition of Herpesvirus Proteases

por Gable, Jonathan E., Lee, Gregory M., Jaishankar, Priyadarshini, Hearn, Brian R., Waddling, Christopher A., Renslo, Adam R., Craik, Charles S.
Publicado 2014

A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models

por Spangler, Benjamin, Fontaine, Shaun D., Shi, Yihui, Sambucetti, Lidia, Mattis, Aras N., Hann, Byron, Wells, James A., Renslo, Adam R.
Publicado 2016

A High-Throughput Functional Screen Identifies Small Molecule Regulators of Temperature- and Mechano-Sensitive K(2P) Channels

por Bagriantsev, Sviatoslav N., Ang, Kean-Hooi, Gallardo-Godoy, Alejandra, Clark, Kimberly A., Arkin, Michelle R., Renslo, Adam R., Minor, Daniel L.
Publicado 2013

A reactivity-based probe of the intracellular labile ferrous iron pool

por Spangler, Benjamin, Morgan, Charles W., Fontaine, Shaun D., Vander Wal, Mark N., Chang, Christopher J., Wells, James A., Renslo, Adam R.
Publicado 2016

Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening

por Abdulla, Maha-Hamadien, Ruelas, Debbie S., Wolff, Brian, Snedecor, June, Lim, Kee-Chong, Xu, Fengyun, Renslo, Adam R., Williams, Janice, McKerrow, James H., Caffrey, Conor R.
Publicado 2009

Hypothemicin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei

por Nishino, Mari, Choy, Jonathan W, Gushwa, Nathan N, Oses-Prieto, Juan A, Koupparis, Kyriacos, Burlingame, Alma L, Renslo, Adam R, McKerrow, James H, Taunton, Jack
Publicado 2013

Correction: Hypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei

por Nishino, Mari, Choy, Jonathan W, Gushwa, Nathan N, Oses-Prieto, Juan A, Koupparis, Kyriacos, Burlingame, Alma L, Renslo, Adam R, McKerrow, James H, Taunton, Jack
Publicado 2013

Protease inhibitors targeting coronavirus and filovirus entry

por Zhou, Yanchen, Vedantham, Punitha, Lu, Kai, Agudelo, Juliet, Carrion, Ricardo, Nunneley, Jerritt W., Barnard, Dale, Pöhlmann, Stefan, McKerrow, James H., Renslo, Adam R., Simmons, Graham
Publicado 2015

cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool

por Camarena, Vladimir, Sant, David W, Huff, Tyler C, Mustafi, Sushmita, Muir, Ryan K, Aron, Allegra T, Chang, Christopher J, Renslo, Adam R, Monje, Paula V, Wang, Gaofeng
Publicado 2017