No evidence for age-related differences in mitochondrial RNA quality in the female germline

por Hartley, Fiona, Alageel, Arwa, Appeltant, Ruth, Gray, Nicki, Repapi, Emmanouela, Wells, Dagan, Williams, Suzannah A, Poulton, Joanna
Publicado 2022

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

por Monteiro, Rui, Pinheiro, Philip, Joseph, Nicola, Peterkin, Tessa, Koth, Jana, Repapi, Emmanouela, Bonkhofer, Florian, Kirmizitas, Arif, Patient, Roger
Publicado 2016

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

por Merryweather-Clarke, Alison T., Cook, David, Lara, Barbara Joo, Hua, Peng, Repapi, Emmanouela, Ashley, Neil, Lim, Shiang Y., Watt, Suzanne M.
Publicado 2018

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo

por Lukoseviciute, Martyna, Gavriouchkina, Daria, Williams, Ruth M., Hochgreb-Hagele, Tatiana, Senanayake, Upeka, Chong-Morrison, Vanessa, Thongjuea, Supat, Repapi, Emmanouela, Mead, Adam, Sauka-Spengler, Tatjana
Publicado 2018

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo

por Williams, Ruth M., Candido-Ferreira, Ivan, Repapi, Emmanouela, Gavriouchkina, Daria, Senanayake, Upeka, Ling, Irving T.C., Telenius, Jelena, Taylor, Stephen, Hughes, Jim, Sauka-Spengler, Tatjana
Publicado 2019

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

por Zhang, Yonghong, Makvandi-Nejad, Shokouh, Qin, Ling, Zhao, Yan, Zhang, Tong, Wang, Lili, Repapi, Emmanouela, Taylor, Stephen, McMichael, Andrew, Li, Ning, Dong, Tao, Wu, Hao
Publicado 2015

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation

por Godfrey, Laura, Kerry, Jon, Thorne, Ross, Repapi, Emmanouela, Davies, James O.J., Tapia, Marta, Ballabio, Erica, Hughes, Jim R., Geng, Huimin, Konopleva, Marina, Milne, Thomas A.
Publicado 2017

BET inhibition disrupts transcription but retains enhancer-promoter contact

por Crump, Nicholas T., Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O. J., Milne, Thomas A.
Publicado 2021

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

por Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Publicado 2017

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

por Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.
Publicado 2019

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin

por Truch, Julia, Downes, Damien J., Scott, Caroline, Gür, E. Ravza, Telenius, Jelena M., Repapi, Emmanouela, Schwessinger, Ron, Gosden, Matthew, Brown, Jill M., Taylor, Stephen, Cheong, Pak Leng, Hughes, Jim R., Higgs, Douglas R., Gibbons, Richard J.
Publicado 2022

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide

por Ramcharan, Roger, Aleksic, Tamara, Kamdoum, Wilfride Petnga, Gao, Shan, Pfister, Sophia X., Tanner, Jordan, Bridges, Esther, Asher, Ruth, Watson, Amanda J., Margison, Geoffrey P., Woodcock, Mick, Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R., Macaulay, Valentine M.
Publicado 2015

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

por Chagraoui, Hedia, Kristiansen, Maiken S., Ruiz, Juan Pablo, Serra-Barros, Ana, Richter, Johanna, Hall-Ponselé, Elisa, Gray, Nicki, Waithe, Dominic, Clark, Kevin, Hublitz, Philip, Repapi, Emmanouela, Otto, Georg, Sopp, Paul, Taylor, Stephen, Thongjuea, Supat, Vyas, Paresh, Porcher, Catherine
Publicado 2018

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort

por Zhang, Yong-Hong, Zhao, Yan, Rajapaksa, Ushani S., Lawrence, Tessa M., Peng, Yan-Chun, Liu, Jinghua, Xu, Keyi, Hu, Ke, Qin, Ling, Liu, Ning, Sun, Huanqin, Yan, Hui-Ping, Repapi, Emmanouela, Rowland-Jones, Sarah, Thimme, Robert, McKeating, Jane A., Dong, Tao
Publicado 2016

Heterogeneity of human lympho-myeloid progenitors at the single cell level

por Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Gottgens, Berthold, Vyas, Paresh
Publicado 2017

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation

por Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A.G., Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M., Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J.
Publicado 2019

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

por Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Publicado 2017

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

por Gooding, Sarah, Olechnowicz, Sam W. Z., Morris, Emma V., Armitage, Andrew E., Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R., Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J., Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M.
Publicado 2019

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

por Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M. D., Hardman, Clare S., Alham, Nasullah K., Rigby, Rachel E., Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Publicado 2021

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation

por Mead, Adam J., Neo, Wen Hao, Barkas, Nikolaos, Matsuoka, Sahoko, Giustacchini, Alice, Facchini, Raffaella, Thongjuea, Supat, Jamieson, Lauren, Booth, Christopher A.G., Fordham, Nicholas, Di Genua, Cristina, Atkinson, Deborah, Chowdhury, Onima, Repapi, Emmanouela, Gray, Nicki, Kharazi, Shabnam, Clark, Sally-Ann, Bouriez, Tiphaine, Woll, Petter, Suda, Toshio, Nerlov, Claus, Jacobsen, Sten Eirik W.
Publicado 2017