Reassessing target antigens for adoptive T cell therapy

por Hinrichs, Christian S., Restifo, Nicholas P.
Publicado 2013

Inhibition of the T cell oxygen sensing machinery promotes anti-tumor efficacy

por Clever, David, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado 2015

Modulating immunometabolism of tumor specific CD8 T cells to enhance T cell based therapy for cancer

por Sukumar, Madhusudhanan, Liu, Jie, Mehta, Gautam, Gattinoni, Luca, Finkel, Toren, Restifo, Nicholas
Publicado 2014

Cish attenuates proximal TCR-signaling and CD8+ T cell immunity

por Palmer, Douglas, Guittard, Geoffery, Patel, Shashank, Samelson, Lawrence E, Restifo, Nicholas P
Publicado 2014

Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors

por Overwijk, Willem W, Wang, Ena, Marincola, Francesco M, Rammensee, Hans-Georg, Restifo, Nicholas P
Publicado 2013

Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells

por Church, Sarah E, Jensen, Shawn M, Antony, Paul A, Restifo, Nicholas P, Fox, Bernard A
Publicado 2014

Predominant Role for Directly Transfected Dendritic Cells in Antigen Presentation to CD8(+) T Cells after Gene Gun Immunization

por Porgador, Angel, Irvine, Kari R., Iwasaki, Akiko, Barber, Brian H., Restifo, Nicholas P., Germain, Ronald N.
Publicado 1998

Mitochondrial activity regulates T cell memory, self renewal and anti tumor function in CD8+ T cells

por Sukumar, Madhusudhanan, Liu, Jie, Crompton, Joseph, Rao, Mahadev, Ji, Yun, Finkel, Toren, Gattinoni, Luca, Restifo, Nicholas
Publicado 2013

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

por Tran, Eric, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Morgan, Richard A., Lee, Chyi-Chia Richard, Restifo, Nicholas P., Rosenberg, Steven A.
Publicado 2013

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models

por Zhang, Ling, Davies, John S, Serna, Carylinda, Yu, Zhiya, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A, Hinrichs, Christian S
Publicado 2020

Fas expression in memory CD8+ T cell subsets augments cellular differentiation and effector function

por Yamamoto, Tori, Leonardi, Anthony, Liu, Hui, Wang, Ena, Gattinoni, Luca, Cruz, Anthony, Ouyang, Claudia, Siegel, Richard, Restifo, Nicholas, Klebanoff, Christopher A
Publicado 2015

The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8(+) T cells

por Guittard, Geoffrey, Dios-Esponera, Ana, Palmer, Douglas C., Akpan, Itoro, Barr, Valarie A., Manna, Asit, Restifo, Nicholas P., Samelson, Lawrence E.
Publicado 2018

Elevated potassium levels suppress T cell activation within tumors

por Eil, Robert L, Roychoudhuri, Rahul, Clever, David, Patel, Shashank, Sukumar, Madhu, Pan, Jenny H, Palmer, Douglas, Klebanoff, Christopher A, Restifo, Nicholas P
Publicado 2015

Viral Sequestration of Antigen Subverts Cross Presentation to CD8(+) T Cells

por Tewalt, Eric F., Grant, Jean M., Granger, Erica L., Palmer, Douglas C., Heuss, Neal D., Gregerson, Dale S., Restifo, Nicholas P., Norbury, Christopher C.
Publicado 2009

Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma

por Xie, Ying, Akpinarli, Akgül, Maris, Charles, Hipkiss, Edward L., Lane, Malcolm, Kwon, Eun-Kyung M., Muranski, Pawel, Restifo, Nicholas P., Antony, Paul Andrew
Publicado 2010

Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells

por Klebanoff, Christopher A, Spencer, Sean, Roychoudhuri, Rahu, Ji, Yun, Sukumar, Madhu, Muranski, Pawel, Napoli, Joseph L, Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P
Publicado 2013

Immune Evasion by Murine Melanoma Mediated through CC Chemokine Receptor-10

por Murakami, Takashi, Cardones, Adela R., Finkelstein, Steven E., Restifo, Nicholas P., Klaunberg, Brenda A., Nestle, Frank O., Castillo, S. Sianna, Dennis, Phillip A., Hwang, Sam T.
Publicado 2003

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

por Ji, Yun, Abrams, Natalie, Zhu, Wei, Salinas, Eddie, Yu, Zhiya, Palmer, Douglas C., Jailwala, Parthav, Franco, Zulmarie, Roychoudhuri, Rahul, Stahlberg, Eric, Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2014

Cish actively silences tcr signaling in CD8+ T cells to maintain tumor tolerance

por Palmer, Douglas, Guittard, Geoff, Franco, Zulmarie, Patel, Shashank, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Eil, Robert L, Clever, David, Balagopalan, Lakshmi, Roychoudhuri, Rahul, Samelson, Larry, Restifo, Nicholas
Publicado 2015

Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer

por Sukumar, Madhusudhanan, Liu, Jie, Patel, Shashank J, Klebanoff, Christopher A, Mehta, Gautam, Roychoudhuri, Rahul, Crompton, Joseph, Clever, David, Gattinoni, Luca, Muranski, Pawel, Finkel, Toren, Restifo, Nicholas
Publicado 2015