Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain

por Retamal, Jeffri S., Ramírez-García, Paulina D., Shenoy, Priyank A., Poole, Daniel P., Veldhuis, Nicholas A.
Publicado 2019

Burst-Like Subcutaneous Electrical Stimulation Induces BDNF-Mediated, Cyclotraxin B-Sensitive Central Sensitization in Rat Spinal Cord

por Retamal, Jeffri, Reyes, Andrea, Ramirez, Paulina, Bravo, David, Hernandez, Alejandro, Pelissier, Teresa, Villanueva, Luis, Constandil, Luis
Publicado 2018

NMDA and P2X7 Receptors Require Pannexin 1 Activation to Initiate and Maintain Nociceptive Signaling in the Spinal Cord of Neuropathic Rats

por Bravo, David, Zepeda-Morales, Katherine, Maturana, Carola J., Retamal, Jeffri S., Hernández, Alejandro, Pelissier, Teresa, Barra, Rafael, Sáez-Briones, Patricio, Burgos, Héctor, Constandil, Luis
Publicado 2022

Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice

por Retamal, Jeffri S., Grace, Megan S., Dill, Larissa K., Ramirez-Garcia, Paulina, Peng, Scott, Gondin, Arisbel B., Bennetts, Felix, Alvi, Sadia, Rajasekhar, Pradeep, Almazi, Juhura G., Carbone, Simona E., Bunnett, Nigel W., Davis, Thomas P., Veldhuis, Nicholas A., Poole, Daniel P., McIntyre, Peter
Publicado 2021

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

por De Logu, Francesco, Nassini, Romina, Hegron, Alan, Landini, Lorenzo, Jensen, Dane D., Latorre, Rocco, Ding, Julia, Marini, Matilde, Souza Monteiro de Araujo, Daniel, Ramírez-Garcia, Paulina, Whittaker, Michael, Retamal, Jeffri, Titiz, Mustafa, Innocenti, Alessandro, Davis, Thomas P., Veldhuis, Nicholas, Schmidt, Brian L., Bunnett, Nigel W., Geppetti, Pierangelo
Publicado 2022

Mice expressing fluorescent PAR(2) reveal that endocytosis mediates colonic inflammation and pain

por Latorre, Rocco, Hegron, Alan, Peach, Chloe J., Teng, Shavonne, Tonello, Raquel, Retamal, Jeffri S., Klein-Cloud, Rafael, Bok, Diana, Jensen, Dane D., Gottesman-Katz, Lena, Rientjes, Jeanette, Veldhuis, Nicholas A., Poole, Daniel P., Schmidt, Brian L., Pothoulakis, Charalabos H., Rankin, Carl, Xie, Ying, Koon, Hon Wai, Bunnett, Nigel W.
Publicado 2022

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

por Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L., Veldhuis, Nicholas A.
Publicado 2021