Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin

por Retta, Saverio Francesco, Glading, Angela J.
Publicado 2016

The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications

por Ferro, Elisa, Goitre, Luca, Retta, Saverio Francesco, Trabalzini, Lorenza
Publicado 2012

Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk?

por Goitre, Luca, Pergolizzi, Barbara, Ferro, Elisa, Trabalzini, Lorenza, Retta, Saverio Francesco
Publicado 2012

Reactive Oxygen Species: Friends and Foes of Signal Transduction

por Retta, Saverio Francesco, Chiarugi, Paola, Trabalzini, Lorenza, Pinton, Paolo, Belkin, Alexey M.
Publicado 2012

Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations

por Antognelli, Cinzia, Perrelli, Andrea, Armeni, Tatiana, Nicola Talesa, Vincenzo, Retta, Saverio Francesco
Publicado 2020

miR-21 coordinates tumor growth and modulates KRIT1 levels

por Orso, Francesca, Balzac, Fiorella, Marino, Marco, Lembo, Antonio, Retta, Saverio Francesco, Taverna, Daniela
Publicado 2013

Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies

por Marchi, Saverio, Trapani, Eliana, Corricelli, Mariangela, Goitre, Luca, Pinton, Paolo, Retta, Saverio Francesco
Publicado 2016

Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases

por Perrelli, Andrea, Goitre, Luca, Salzano, Anna Maria, Moglia, Andrea, Scaloni, Andrea, Retta, Saverio Francesco
Publicado 2018

KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species

por Goitre, Luca, Balzac, Fiorella, Degani, Simona, Degan, Paolo, Marchi, Saverio, Pinton, Paolo, Retta, Saverio Francesco
Publicado 2010

Identification of the Kelch Family Protein Nd1-L as a Novel Molecular Interactor of KRIT1

por Guazzi, Paolo, Goitre, Luca, Ferro, Elisa, Cutano, Valentina, Martino, Chiara, Trabalzini, Lorenza, Retta, Saverio Francesco
Publicado 2012

Next-Generation Sequencing Advances the Genetic Diagnosis of Cerebral Cavernous Malformation (CCM)

por Benedetti, Valerio, Canzoneri, Rosalia, Perrelli, Andrea, Arduino, Carlo, Zonta, Andrea, Brusco, Alfredo, Retta, Saverio Francesco
Publicado 2022

The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading

por Degani, Simona, Balzac, Fiorella, Brancaccio, Mara, Guazzone, Simona, Retta, Saverio Francesco, Silengo, Lorenzo, Eva, Alessandra, Tarone, Guido
Publicado 2002

Multifunctional Platinum@BSA–Rapamycin Nanocarriers for the Combinatorial Therapy of Cerebral Cavernous Malformation

por De Luca, Elisa, Pedone, Deborah, Moglianetti, Mauro, Pulcini, Daniele, Perrelli, Andrea, Retta, Saverio Francesco, Pompa, Pier Paolo
Publicado 2018

Multidrug-Loaded Lipid Nanoemulsions for the Combinatorial Treatment of Cerebral Cavernous Malformation Disease

por Perrelli, Andrea, Bozza, Annalisa, Ferraris, Chiara, Osella, Sara, Moglia, Andrea, Mioletti, Silvia, Battaglia, Luigi, Retta, Saverio Francesco
Publicado 2023

Vitamin D Deficiency and the Risk of Cerebrovascular Disease

por Kim, Hyun Ah, Perrelli, Andrea, Ragni, Alberto, Retta, Francesca, De Silva, T. Michael, Sobey, Christopher G., Retta, Saverio Francesco
Publicado 2020

Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function

por Antognelli, Cinzia, Trapani, Eliana, Delle Monache, Simona, Perrelli, Andrea, Fornelli, Claudia, Retta, Francesca, Cassoni, Paola, Talesa, Vincenzo Nicola, Retta, Saverio Francesco
Publicado 2017

KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun

por Goitre, Luca, De Luca, Elisa, Braggion, Stefano, Trapani, Eliana, Guglielmotto, Michela, Biasi, Fiorella, Forni, Marco, Moglia, Andrea, Trabalzini, Lorenza, Retta, Saverio Francesco
Publicado 2014

Yeast-Derived Recombinant Avenanthramides Inhibit Proliferation, Migration and Epithelial Mesenchymal Transition of Colon Cancer Cells

por Finetti, Federica, Moglia, Andrea, Schiavo, Irene, Donnini, Sandra, Berta, Giovanni Nicolao, Di Scipio, Federica, Perrelli, Andrea, Fornelli, Claudia, Trabalzini, Lorenza, Retta, Saverio Francesco
Publicado 2018

Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress

por Mastrocola, Raffaella, Aimaretti, Eleonora, Ferreira Alves, Gustavo, Cento, Alessia Sofia, Fornelli, Claudia, Dal Bello, Federica, Ferraris, Chiara, Goitre, Luca, Perrelli, Andrea, Retta, Saverio Francesco
Publicado 2022

Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1

por Choquet, Hélène, Trapani, Eliana, Goitre, Luca, Trabalzini, Lorenza, Akers, Amy, Fontanella, Marco, Hart, Blaine L., Morrison, Leslie A., Pawlikowska, Ludmila, Kim, Helen, Retta, Saverio Francesco
Publicado 2016