STIMULATION BY ENDOCYTOSIS OF THE SECRETION OF COLLAGENASE AND NEUTRAL PROTEINASE FROM RABBIT SYNOVIAL FIBROBLASTS

por Werb, Zena, Reynolds, John J.
Publicado 1974

Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair

por Reynolds, John J., Walker, Alexandra K., Gilmore, Edward C., Walsh, Christopher A., Caldecott, Keith W.
Publicado 2012

Expanding the ataxia with oculomotor apraxia type 4 phenotype

por Paucar, Martin, Malmgren, Helena, Taylor, Malcolm, Reynolds, John J., Svenningsson, Per, Press, Rayomand, Nordgren, Ann
Publicado 2016

Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ

por Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J., Stewart, Grant S., Wollnik, Bernd, Yigit, Gökhan, Caldecott, Keith W.
Publicado 2019

DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain

por Zhang, Jing, Bellani, Marina A., James, Ryan C., Pokharel, Durga, Zhang, Yongqing, Reynolds, John J., McNee, Gavin S., Jackson, Andrew P., Stewart, Grant S., Seidman, Michael M.
Publicado 2020

PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination

por Clarke, Thomas L., Sanchez-Bailon, Maria Pilar, Chiang, Kelly, Reynolds, John J., Herrero-Ruiz, Joaquin, Bandeiras, Tiago M., Matias, Pedro M., Maslen, Sarah L., Skehel, J. Mark, Stewart, Grant S., Davies, Clare C.
Publicado 2017

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

por Higgs, Martin R., Sato, Koichi, Reynolds, John J., Begum, Shabana, Bayley, Rachel, Goula, Amalia, Vernet, Audrey, Paquin, Karissa L., Skalnik, David G., Kobayashi, Wataru, Takata, Minoru, Howlett, Niall G., Kurumizaka, Hitoshi, Kimura, Hiroshi, Stewart, Grant S.
Publicado 2018

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

por Shen, Jun, Gilmore, Edward C., Marshall, Christine A., Haddadin, Mary, Reynolds, John J., Eyaid, Wafaa, Bodell, Adria, Allen, Kathryn, Chang, Bernard S., Grix, Arthur, Hill, R. Sean, Topcu, Meral, Caldecott, Keith W., Barkovich, A. James, Walsh, Christopher A.
Publicado 2010

Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer

por Read, Martin L., Fong, Jim C.W., Modasia, Bhavika, Fletcher, Alice, Imruetaicharoenchoke, Waraporn, Thompson, Rebecca, Nieto, Hannah, Reynolds, John J., Bacon, Andrea, Mallick, Ujjal, Hackshaw, Allan, Watkinson, John C., Boelaert, Kristien, Turnell, Andrew S., Smith, Vicki E., McCabe, Christopher J.
Publicado 2017

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

por Patel, Parasvi S, Algouneh, Arash, Krishnan, Rehna, Reynolds, John J, Nixon, Kevin C J, Hao, Jun, Lee, Jihoon, Feng, Yue, Fozil, Chehronai, Stanic, Mia, Yerlici, Talya, Su, Peiran, Soares, Fraser, Liedtke, Elisabeth, Prive, Gil, Baider, Gary D, Pujana, Miquel Angel, Mekhail, Karim, He, Housheng Hansen, Hakem, Anne, Stewart, Grant S, Hakem, Razqallah
Publicado 2023

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

por Abu-Libdeh, Bassam, Jhujh, Satpal S., Dhar, Srijita, Sommers, Joshua A., Datta, Arindam, Longo, Gabriel M.C., Grange, Laura J., Reynolds, John J., Cooke, Sophie L., McNee, Gavin S., Hollingworth, Robert, Woodward, Beth L., Ganesh, Anil N., Smerdon, Stephen J., Nicolae, Claudia M., Durlacher-Betzer, Karina, Molho-Pessach, Vered, Abu-Libdeh, Abdulsalam, Meiner, Vardiella, Moldovan, George-Lucian, Roukos, Vassilis, Harel, Tamar, Brosh, Robert M., Stewart, Grant S.
Publicado 2022

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

por Krishnan, Rehna, Lapierre, Mariah, Gautreau, Brandon, Nixon, Kevin C J, El Ghamrasni, Samah, Patel, Parasvi S, Hao, Jun, Yerlici, V Talya, Guturi, Kiran Kumar Naidu, St-Germain, Jonathan, Mateo, Francesca, Saad, Amine, Algouneh, Arash, Earnshaw, Rebecca, Shili, Duan, Seitova, Alma, Miller, Joshua, Khosraviani, Negin, Penn, Adam, Ho, Brandon, Sanchez, Otto, Hande, M Prakash, Masson, Jean-Yves, Brown, Grant W, Alaoui-Jamali, Moulay, Reynolds, John J, Arrowsmith, Cheryl, Raught, Brian, Pujana, Miguel A, Mekhail, Karim, Stewart, Grant S, Hakem, Anne, Hakem, Razqallah
Publicado 2023

Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy

por Grange, Laura J., Reynolds, John J., Ullah, Farid, Isidor, Bertrand, Shearer, Robert F., Latypova, Xenia, Baxley, Ryan M., Oliver, Antony W., Ganesh, Anil, Cooke, Sophie L., Jhujh, Satpal S., McNee, Gavin S., Hollingworth, Robert, Higgs, Martin R., Natsume, Toyoaki, Khan, Tahir, Martos-Moreno, Gabriel Á., Chupp, Sharon, Mathew, Christopher G., Parry, David, Simpson, Michael A., Nahavandi, Nahid, Yüksel, Zafer, Drasdo, Mojgan, Kron, Anja, Vogt, Petra, Jonasson, Annemarie, Seth, Saad Ahmed, Gonzaga-Jauregui, Claudia, Brigatti, Karlla W., Stegmann, Alexander P. A., Kanemaki, Masato, Josifova, Dragana, Uchiyama, Yuri, Oh, Yukiko, Morimoto, Akira, Osaka, Hitoshi, Ammous, Zineb, Argente, Jesús, Matsumoto, Naomichi, Stumpel, Constance T.R.M., Taylor, Alexander M. R., Jackson, Andrew P., Bielinsky, Anja-Katrin, Mailand, Niels, Le Caignec, Cedric, Davis, Erica E., Stewart, Grant S.
Publicado 2022