Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma

por Lee, Alexander H., Sun, Lu, Mochizuki, Aaron Y., Reynoso, Jeremy G., Orpilla, Joey, Chow, Frances, Kienzler, Jenny C., Everson, Richard G., Nathanson, David A., Bensinger, Steven J., Liau, Linda M., Cloughesy, Timothy, Hugo, Willy, Prins, Robert M.
Publicado 2021

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma

por Hu, Junhui, Tan, Ping, Ishihara, Moe, Bayley, Nicholas A., Schokrpur, Shiruyeh, Reynoso, Jeremy G., Zhang, Yangjun, Lim, Raymond J., Dumitras, Camelia, Yang, Lu, Dubinett, Steven M., Jat, Parmjit S., Van Snick, Jacques, Huang, Jiaoti, Chin, Arnold I., Prins, Robert M., Graeber, Thomas G., Xu, Hua, Wu, Lily
Publicado 2023

Immune checkpoint blockade induces distinct alterations in the microenvironments of primary and metastatic brain tumors

por Sun, Lu, Kienzler, Jenny C., Reynoso, Jeremy G., Lee, Alexander, Shiuan, Eileen, Li, Shanpeng, Kim, Jiyoon, Ding, Lizhong, Monteleone, Amber J., Owens, Geoffrey C., Phillips, Joanna J., Everson, Richard G., Nathanson, David, Cloughesy, Timothy F., Li, Gang, Liau, Linda M., Hugo, Willy, Kim, Won, Prins, Robert M.
Publicado 2023