Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT‐4202), an Allosteric Activator of Pyruvate Kinase‐R, in Healthy Adults: A Randomized, Placebo‐Controlled, Double‐Bl...

por Forsyth, Sanjeev, Schroeder, Patricia, Geib, James, Vrishabhendra, Leela, Konstantinidis, Diamantis G., LaSalvia, Kari, Ribadeneira, Maria D., Wu, Eric, Kelly, Patrick, Kalfa, Theodosia A.
Publicado 2022

Concomitant administration of sGC stimulators with common classes of anti-hypertensive agents results in increased efficacy in spontaneously hypertensive rats

por Germano, Peter, Tobin, Jenny, Jefferson, Robert, Shea, Courtney, Smith, Adaline, Jamie Im, G-Yoon, Sheppeck, James, Wakefield, James, Sykes, Kristie, Ribadeneira, Maria, Rivers, Samuel, Masferrer, Jaime
Publicado 2015

Inhibition of fatty acid synthase with FT‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two e...

por Beysen, Carine, Schroeder, Patricia, Wu, Eric, Brevard, Julie, Ribadeneira, Maria, Lu, Wei, Dole, Kiran, O'Reilly, Terry, Morrow, Linda, Hompesch, Marcus, Hellerstein, Marc K., Li, Kelvin, Johansson, Lars, Kelly, Patrick F.
Publicado 2020

KCNQ channel openers reverse depressive symptoms via an active resilience mechanism

por Friedman, Allyson K., Juarez, Barbara, Ku, Stacy M., Zhang, Hongxing, Calizo, Rhodora C., Walsh, Jessica J., Chaudhury, Dipesh, Zhang, Song, Hawkins, Angel, Dietz, David M., Murrough, James W., Ribadeneira, Maria, Wong, Erik H., Neve, Rachael L., Han, Ming-Hu
Publicado 2016