Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers

por Ribas, Ricardo, Ghazoui, Zara, Gao, Qiong, Pancholi, Sunil, Rani, Aradhana, Dunbier, Anita, Dowsett, Mitch, Martin, Lesley-Ann
Publicado 2014

Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments

por Ribas, Ricardo, Moncaut, Natalia, Siligan, Christine, Taylor, Kevin, Cross, Joe W., Rigby, Peter W.J., Carvajal, Jaime J.
Publicado 2011

Involving multiple stakeholders in assessing and reviewing a novel data visualisation tool for a national neonatal data asset

por Lammons, William Bishop, Moss, Becky, Bignell, Charlie, Gale, Chris, MacBride, Adam, Ribas, Ricardo, Battersby, Cheryl, Modi, Neena
Publicado 2023

Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation

por Guest, Stephanie K., Ribas, Ricardo, Pancholi, Sunil, Nikitorowicz-Buniak, Joanna, Simigdala, Nikiana, Dowsett, Mitch, Johnston, Stephen R., Martin, Lesley-Ann
Publicado 2016

Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease

por Simigdala, Nikiana, Pancholi, Sunil, Ribas, Ricardo, Folkerd, Elizabeth, Liccardi, Gianmaria, Nikitorowicz-Buniak, Joanna, Johnston, Stephen R., Dowsett, Mitch, Martin, Lesley-Ann
Publicado 2018

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

por Simigdala, Nikiana, Gao, Qiong, Pancholi, Sunil, Roberg-Larsen, Hanne, Zvelebil, Marketa, Ribas, Ricardo, Folkerd, Elizabeth, Thompson, Andrew, Bhamra, Amandeep, Dowsett, Mitch, Martin, Lesley-Ann
Publicado 2016

ESR1 Is Co-Expressed with Closely Adjacent Uncharacterised Genes Spanning a Breast Cancer Susceptibility Locus at 6q25.1

por Dunbier, Anita K., Anderson, Helen, Ghazoui, Zara, Lopez-Knowles, Elena, Pancholi, Sunil, Ribas, Ricardo, Drury, Suzanne, Sidhu, Kally, Leary, Alexandra, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2011

Elacestrant demonstrates strong anti-estrogenic activity in PDX models of estrogen-receptor positive endocrine-resistant and fulvestrant-resistant breast cancer

por Pancholi, Sunil, Simigdala, Nikiana, Ribas, Ricardo, Schuster, Eugene, Leal, Mariana Ferreira, Nikitorowicz-Buniak, Joanna, Rega, Camilla, Bihani, Teeru, Patel, Hitisha, Johnston, Stephen R., Dowsett, Mitch, Martin, Lesley-Ann
Publicado 2022

Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations

por Lopez-Knowles, Elena, Pearson, Alex, Schuster, Gene, Gellert, Pascal, Ribas, Ricardo, Yeo, Belinda, Cutts, Ros, Buus, Richard, Garcia-Murillas, Isaac, Haynes, Ben, Martin, Lesley-Ann, Smith, Ian, Turner, Nick, Dowsett, Mitch
Publicado 2018

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo

por Martin, Lesley-Ann, Pancholi, Sunil, Farmer, Ian, Guest, Stephanie, Ribas, Ricardo, Weigel, Marion T, Thornhill, Allan M, Ghazoui, Zara, A'Hern, Roger, Evans, Dean B, Lane, Heidi A, Johnston, Stephen R, Dowsett, Mitch
Publicado 2012

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

por Ribas, Ricardo, Pancholi, Sunil, Rani, Aradhana, Schuster, Eugene, Guest, Stephanie K., Nikitorowicz-Buniak, Joanna, Simigdala, Nikiana, Thornhill, Allan, Avogadri-Connors, Francesca, Cutler, Richard E., Lalani, Alshad S., Dowsett, Mitch, Johnston, Stephen R., Martin, Lesley-Ann
Publicado 2018

Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

por Pancholi, Sunil, Leal, Mariana Ferreira, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Chateau-Joubert, Sophie, Zabaglo, Lila, Hills, Margaret, Dodson, Andrew, Gao, Qiong, Johnston, Stephen R., Dowsett, Mitch, Cosulich, Sabina C., Maragoni, Elisabetta, Martin, Lesley-Ann
Publicado 2019

Correction to: Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

por Pancholi, Sunil, Leal, Mariana Ferreira, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Chateau-Joubert, Sophie, Zabaglo, Lila, Hills, Margaret, Dodson, Andrew, Gao, Qiong, Johnston, Stephen R., Dowsett, Mitch, Cosulich, Sabina C., Marangoni, Elisabetta, Martin, Lesley-Ann
Publicado 2020

Pilot feasibility study of a digital technology approach to the systematic electronic capture of parent-reported data on cognitive and language development in children aged 2 years

por Modi, Neena, Ribas, Ricardo, Johnson, Samantha, Lek, Elizabeth, Godambe, Sunit, Fukari-Irvine, Edit, Ogundipe, Enitan, Tusor, Nora, Das, Nayan, Udayakumaran, Abinithya, Moss, Becky, Banda, Victor, Ougham, Kayleigh, Cornelius, Victoria, Arasu, Anusha, Wardle, Steve, Battersby, Cheryl, Bravery, Amanda
Publicado 2023

Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer

por López-Knowles, Elena, Wilkerson, Paul M, Ribas, Ricardo, Anderson, Helen, Mackay, Alan, Ghazoui, Zara, Rani, Aradhana, Osin, Peter, Nerurkar, Ash, Renshaw, Lorna, Larionov, Alexey, Miller, William R, Dixon, J Michael, Reis-Filho, Jorge S, Dunbier, Anita K, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2015

Major Impact of Sampling Methodology on Gene Expression in Estrogen Receptor–Positive Breast Cancer

por Gao, Qiong, López-Knowles, Elena, U Cheang, Maggie Chon, Morden, James, Ribas, Ricardo, Sidhu, Kally, Evans, David, Martins, Vera, Dodson, Andrew, Skene, Anthony, Holcombe, Chris, Mallon, Elizabeth, Evans, Abigail, Bliss, Judith M, Robertson, John, Smith, Ian, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2018

Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients

por Gao, Qiong, López-Knowles, Elena, Cheang, Maggie Chon U., Morden, James, Ribas, Ricardo, Sidhu, Kally, Evans, David, Martins, Vera, Dodson, Andrew, Skene, Anthony, Holcombe, Chris, Mallon, Elizabeth, Evans, Abigail, Bliss, Judith M., Robertson, John, Smith, Ian, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2019

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

por Pancholi, Sunil, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Nikitorowicz-Buniak, Joanna, Ressa, Anna, Gao, Qiong, Leal, Mariana Ferreira, Bhamra, Amandeep, Thornhill, Allan, Morisset, Ludivine, Montaudon, Elodie, Sourd, Laura, Fitzpatrick, Martin, Altelaar, Maarten, Johnston, Stephen R., Marangoni, Elisabetta, Dowsett, Mitch, Martin, Lesley-Ann
Publicado 2020

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

por Martin, Lesley-Ann, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Pancholi, Sunil, Tenev, Tencho, Gellert, Pascal, Buluwela, Laki, Harrod, Alison, Thornhill, Allan, Nikitorowicz-Buniak, Joanna, Bhamra, Amandeep, Turgeon, Marc-Olivier, Poulogiannis, George, Gao, Qiong, Martins, Vera, Hills, Margaret, Garcia-Murillas, Isaac, Fribbens, Charlotte, Patani, Neill, Li, Zheqi, Sikora, Matthew J., Turner, Nicholas, Zwart, Wilbert, Oesterreich, Steffi, Carroll, Jason, Ali, Simak, Dowsett, Mitch
Publicado 2017

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

por Montaudon, Elodie, Nikitorowicz-Buniak, Joanna, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Huguet, Léa, Dahmani, Ahmed, Painsec, Pierre, Nemati, Fariba, Vacher, Sophie, Chemlali, Walid, Masliah-Planchon, Julien, Château-Joubert, Sophie, Rega, Camilla, Leal, Mariana Ferreira, Simigdala, Nikiana, Pancholi, Sunil, Ribas, Ricardo, Nicolas, André, Meseure, Didier, Vincent-Salomon, Anne, Reyes, Cécile, Rapinat, Audrey, Gentien, David, Larcher, Thibaut, Bohec, Mylène, Baulande, Sylvain, Bernard, Virginie, Decaudin, Didier, Coussy, Florence, Le Romancer, Muriel, Dutertre, Guillaume, Tariq, Zakia, Cottu, Paul, Driouch, Keltouma, Bièche, Ivan, Martin, Lesley-Ann, Marangoni, Elisabetta
Publicado 2020