The measurement and control of high-risk host cell proteins for polysorbate degradation in biologics formulation

por Li, Xuanwen, Wang, Fengqiang, Li, Hong, Richardson, Douglas D, Roush, David J
Publicado 2022

Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

por Dunn, Zachary D., Desai, Jayesh, Leme, Gabriel M., Stoll, Dwight R., Richardson, Douglas D.
Publicado 2019

Automated Data Generation for Raman Spectroscopy Calibrations in Multi-Parallel Mini Bioreactors

por Graf, Alexander, Woodhams, Angus, Nelson, Michael, Richardson, Douglas D., Short, Steven M., Brower, Mark, Hoehse, Marek
Publicado 2022

Multi-angle light scattering as a process analytical technology measuring real-time molecular weight for downstream process control

por Patel, Bhumit A., Gospodarek, Adrian, Larkin, Michael, Kenrick, Sophia A., Haverick, Mark A., Tugcu, Nihal, Brower, Mark A., Richardson, Douglas D.
Publicado 2018

Determination of ultra-trace metal-protein interactions in co-formulated monoclonal antibody drug product by SEC-ICP-MS

por Whitty-Léveillé, Laurence, VanAernum, Zachary L., Pavon, Jorge Alexander, Murphy, Christa, Neal, Katie, Forest, William, Gao, Xinliu, Zhong, Wendy, Richardson, Douglas D., Schuessler, Hillary A.
Publicado 2023

Identification and characterization of a residual host cell protein hexosaminidase B associated with N‐glycan degradation during the stability study of a therapeutic recombinant mo...

por Li, Xuanwen, An, Yan, Liao, Jing, Xiao, Li, Swanson, Michael, Martinez‐Fonts, Kirby, Pavon, Jorge Alexander, Sherer, Edward C., Jawa, Vibha, Wang, Fengqiang, Gao, Xinliu, Letarte, Simon, Richardson, Douglas D.
Publicado 2021

Preclinical immunogenicity and efficacy of a candidate COVID-19 vaccine based on a vesicular stomatitis virus-SARS-CoV-2 chimera

por Espeseth, Amy S., Yuan, Maoli, Citron, Michael, Reiserova, Lucia, Morrow, Gavin, Wilson, Aaron, Horton, Melanie, Rukhman, Mark, Kinek, Keith, Hou, Fuxiang, Li, Shui L., Li, Fengsheng, Choi, Yesle, Heidecker, Gwen, Luo, Bin, Wu, Guoxin, Zhang, Lan, Strable, Erica, DeStefano, Joanne, Secore, Susan, Mukhopadhyay, Tarit K., Richardson, Douglas D., Sayeed, Eddy, Welch, Lisa S., Bett, Andrew J., Feinberg, Mark B., Gupta, Swati B., Cooper, Christopher L., Parks, Christopher L.
Publicado 2022