Modelling Cooperative Tumorigenesis in Drosophila

por Richardson, Helena E., Portela, Marta
Publicado 2018

Two-Faced: Roles of JNK Signalling During Tumourigenesis in the Drosophila Model

por La Marca, John E., Richardson, Helena E.
Publicado 2020

Basic and Translational Models of Cooperative Oncogenesis

por Richardson, Helena E., Cordero, Julia B., Grifoni, Daniela
Publicado 2020

lgl Regulates the Hippo Pathway Independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK

por Parsons, Linda M., Grzeschik, Nicola A., Richardson, Helena E.
Publicado 2014

Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue

por Poon, Carole L.C., Brumby, Anthony M., Richardson, Helena E.
Publicado 2018

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

por Doggett, Karen, Grusche, Felix A, Richardson, Helena E, Brumby, Anthony M
Publicado 2011

In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling

por Khoo, Peytee, Allan, Kirsten, Willoughby, Lee, Brumby, Anthony M., Richardson, Helena E.
Publicado 2013

scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

por Leong, Gregory R, Goulding, Karen R, Amin, Nancy, Richardson, Helena E, Brumby, Anthony M
Publicado 2009

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

por Turkel, Nezaket, Portela, Marta, Poon, Carole, Li, Jason, Brumby, Anthony M., Richardson, Helena E.
Publicado 2015

A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues

por Parsons, Linda M., Grzeschik, Nicola A., Amaratunga, Kasun, Burke, Peter, Quinn, Leonie M., Richardson, Helena E.
Publicado 2017

Debcl, a Proapoptotic Bcl-2 Homologue, Is a Component of the Drosophila melanogaster Cell Death Machinery

por Colussi, Paul A., Quinn, Leonie M., Huang, David C.S., Coombe, Michelle, Read, Stuart H., Richardson, Helena, Kumar, Sharad
Publicado 2000

BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila

por Doggett, Karen, Turkel, Nezaket, Willoughby, Lee F., Ellul, Jason, Murray, Michael J., Richardson, Helena E., Brumby, Anthony M.
Publicado 2015

PTP61F Mediates Cell Competition and Mitigates Tumorigenesis

por La Marca, John E., Willoughby, Lee F., Allan, Kirsten, Portela, Marta, Goh, Pei Kee, Tiganis, Tony, Richardson, Helena E.
Publicado 2021

A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer

por La Marca, John E., Ely, Robert W., Diepstraten, Sarah T., Burke, Peter, Kelly, Gemma L., Humbert, Patrick O., Richardson, Helena E.
Publicado 2023

The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy

por Froldi, Francesca, Ziosi, Marcello, Garoia, Flavio, Pession, Andrea, Grzeschik, Nicola A, Bellosta, Paola, Strand, Dennis, Richardson, Helena E, Pession, Annalisa, Grifoni, Daniela
Publicado 2010

An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

por Willoughby, Lee F., Schlosser, Tanja, Manning, Samuel A., Parisot, John P., Street, Ian P., Richardson, Helena E., Humbert, Patrick O., Brumby, Anthony M.
Publicado 2013

miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

por Daniel, Scott G., Russ, Atlantis D., Guthridge, Kathryn M., Raina, Ammad I., Estes, Patricia S., Parsons, Linda M., Richardson, Helena E., Schroeder, Joyce A., Zarnescu, Daniela C.
Publicado 2017

The BTB-zinc Finger Transcription Factor Abrupt Acts as an Epithelial Oncogene in Drosophila melanogaster through Maintaining a Progenitor-like Cell State

por Turkel, Nezaket, Sahota, Virender K., Bolden, Jessica E., Goulding, Karen R., Doggett, Karen, Willoughby, Lee F., Blanco, Enrique, Martin-Blanco, Enrique, Corominas, Montserrat, Ellul, Jason, Aigaki, Toshiro, Richardson, Helena E., Brumby, Anthony M.
Publicado 2013

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

por Koe, Chwee Tat, Li, Song, Rossi, Fabrizio, Wong, Jack Jing Lin, Wang, Yan, Zhang, Zhizhuo, Chen, Keng, Aw, Sherry Shiying, Richardson, Helena E, Robson, Paul, Sung, Wing-Kin, Yu, Fengwei, Gonzalez, Cayetano, Wang, Hongyan
Publicado 2014

Correction: TSPAN6 is a suppressor of Ras-driven cancer

por Humbert, Patrick O., Pryjda, Tamara Zoranovic, Pranjic, Blanka, Farrell, Andrew, Fujikura, Kohei, de Matos Simoes, Ricardo, Karim, Rezaul, Kozieradzki, Ivona, Cronin, Shane J. F., Neely, G. Gregory, Meyer, Thomas F., Hagelkruys, Astrid, Richardson, Helena E., Penninger, Josef M.
Publicado 2022