Protein restriction and branched‐chain amino acid restriction promote geroprotective shifts in metabolism

por Trautman, Michaela E., Richardson, Nicole E., Lamming, Dudley W.
Publicado 2022

Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging

por Arriola Apelo, Sebastian I, Lin, Amy, Brinkman, Jacqueline A, Meyer, Emma, Morrison, Mark, Tomasiewicz, Jay L, Pumper, Cassidy P, Baar, Emma L, Richardson, Nicole E, Alotaibi, Mohammed, Lamming, Dudley W
Publicado 2020

Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia

por Deem, Jennifer D., Tingley, David, Bjerregaard, Anne-Mette, Secher, Anna, Chan, Owen, Uzo, Chukwuemeka, Richardson, Nicole E., Giering, Elizabeth, Doan, Tammy, Phan, Bao A., Wu, Brandon, Scarlett, Jarrad M., Morton, Gregory J., Schwartz, Michael W.
Publicado 2023

Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

por Brown, Jenny M., Bentsen, Marie A., Rausch, Dylan M., Phan, Bao Anh, Wieck, Danielle, Wasanwala, Huzaifa, Matsen, Miles E., Acharya, Nikhil, Richardson, Nicole E., Zhao, Xin, Zhai, Peng, Secher, Anna, Morton, Gregory J., Pers, Tune H., Schwartz, Michael W., Scarlett, Jarrad M.
Publicado 2021

Fasting drives the metabolic, molecular, and geroprotective effects of a calorie restricted diet in mice

por Pak, Heidi H., Haws, Spencer A., Green, Cara L., Koller, Mikaela, Lavarias, Mitchell T., Richardson, Nicole E., Yang, Shany E., Dumas, Sabrina N., Sonsalla, Michelle, Bray, Lindsey, Johnson, Michelle, Barnes, Stephen, Darley-Usmar, Victor, Zhang, Jianhua, Yen, Chi-Liang Eric, Denu, John M., Lamming, Dudley W.
Publicado 2021

Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice

por Richardson, Nicole E., Konon, Elizabeth N., Schuster, Haley S., Mitchell, Alexis T., Boyle, Colin, Rodgers, Allison C., Finke, Megan, Haider, Lexington R., Yu, Deyang, Flores, Victoria, Pak, Heidi H., Ahmad, Soha, Ahmed, Sareyah, Radcliff, Abigail, Wu, Jessica, Williams, Elizabeth M., Abdi, Lovina, Sherman, Dawn S., Hacker, Timothy, Lamming, Dudley W.
Publicado 2021

Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E(2) Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes...

por Schaid, Michael D., Zhu, Yanlong, Richardson, Nicole E., Patibandla, Chinmai, Ong, Irene M., Fenske, Rachel J., Neuman, Joshua C., Guthery, Erin, Reuter, Austin, Sandhu, Harpreet K., Fuller, Miles H., Cox, Elizabeth D., Davis, Dawn B., Layden, Brian T., Brasier, Allan R., Lamming, Dudley W., Ge, Ying, Kimple, Michelle E.
Publicado 2021