Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study

por Wei, Yuxia, Richardson, Tom G., Zhan, Yiqiang, Carlsson, Sofia
Publicado 2023

Time-varying and tissue-dependent effects of adiposity on leptin levels: A Mendelian randomization study

por Richardson, Tom G, Leyden, Genevieve M, Davey Smith, George
Publicado 2023

Adiposity may confound the association between vitamin D and disease risk – a lifecourse Mendelian randomization study

por Richardson, Tom G, Power, Grace M, Davey Smith, George
Publicado 2022

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

por Richardson, Tom G, Harrison, Sean, Hemani, Gibran, Davey Smith, George
Publicado 2019

The use of negative control outcomes in Mendelian randomization to detect potential population stratification

por Sanderson, Eleanor, Richardson, Tom G, Hemani, Gibran, Davey Smith, George
Publicado 2021

Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization

por Richardson, Tom G, Urquijo, Helena, Holmes, Michael V, Davey Smith, George
Publicado 2023

A lifecourse Mendelian randomization study uncovers age-dependent effects of adiposity on asthma risk

por Urquijo, Helena, Leyden, Genevieve M., Davey Smith, George, Richardson, Tom G.
Publicado 2023

Incorporating Non-Coding Annotations into Rare Variant Analysis

por Richardson, Tom G., Campbell, Colin, Timpson, Nicholas J, Gaunt, Tom R.
Publicado 2016

A pathway-centric approach to rare variant association analysis

por Richardson, Tom G, Timpson, Nicholas J, Campbell, Colin, Gaunt, Tom R
Publicado 2017

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

por Hatcher, Charlie, Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Publicado 2019

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study

por Richardson, Tom G, Sanderson, Eleanor, Elsworth, Benjamin, Tilling, Kate, Davey Smith, George
Publicado 2020

Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data

por Kibinge, Nelson K., Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Publicado 2020

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse—Brief Report

por Richardson, Tom G., O’Nunain, Katie, Relton, Caroline L., Davey Smith, George
Publicado 2022

Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization

por Sanderson, Eleanor, Richardson, Tom G., Morris, Tim T., Tilling, Kate, Davey Smith, George
Publicado 2022

Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications

por Erzurumluoglu, A. Mesut, Baird, Denis, Richardson, Tom G., Timpson, Nicholas J., Rodriguez, Santiago
Publicado 2018

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

por McGowan, Lucy M, Davey Smith, George, Gaunt, Tom R, Richardson, Tom G
Publicado 2019

Evaluating and implementing block jackknife resampling Mendelian randomization to mitigate bias induced by overlapping samples

por Fang, Si, Hemani, Gibran, Richardson, Tom G, Gaunt, Tom R, Davey Smith, George
Publicado 2022

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

por Taylor, Kurt, Davey Smith, George, Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Publicado 2019

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

por Richardson, Tom G., Hemani, Gibran, Gaunt, Tom R., Relton, Caroline L., Davey Smith, George
Publicado 2020

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

por Richardson, Tom G, Fang, Si, Mitchell, Ruth E, Holmes, Michael V, Davey Smith, George
Publicado 2021