A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing

por Jung, Jangwook P., Lin, Wei‐Han, Riddle, Megan J., Tolar, Jakub, Ogle, Brenda M.
Publicado 2018

A homozygous frameshift variant in the KRT5 gene is compatible with life and results in severe recessive epidermolysis bullosa simplex

por Tryon, Rebecca K., Tolar, Jakub, Preusser, Sarah M., Riddle, Megan J., Keene, Douglas R., Bower, Matthew, Thyagarajan, Bharat, Ebens, Christen L.
Publicado 2019

Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production

por Feser, Colby J., Lees, Christopher J., Lammers, Daniel T., Riddle, Megan J., Bingham, Jason R., Eckert, Matthew J., Tolar, Jakub, Osborn, Mark J.
Publicado 2022

Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease

por Thangavelu, Govindarajan, Zaiken, Michael C., Mohamed, Fathima A., Flynn, Ryan, Du, Jing, Rhee, Stephanie Y., Riddle, Megan J., Aguilar, Ethan G., Panoskaltsis-Mortari, Angela, Sanders, Martin E., Blazar, Bruce R.
Publicado 2022

Rapid generation of Col7a1(−/−) mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

por Webber, Beau R., O’Connor, Kyle T., McElmurry, Ron T., Durgin, Elise N., Eide, Cindy, Lees, Christopher J., Riddle, Megan J., Mathews, Wendy, Frank, Natasha Y., Kluth, Mark A., Ganss, Christoph, Moriarity, Branden S., Frank, Markus H., Osborn, Mark J., Tolar, Jakub
Publicado 2017

CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa

por Webber, Beau R, Osborn, Mark J, McElroy, Amber N, Twaroski, Kirk, Lonetree, Cara-lin, DeFeo, Anthony P, Xia, Lily, Eide, Cindy, Lees, Christopher J, McElmurry, Ron T, Riddle, Megan J, Kim, Chong Jai, Patel, Dharmeshkumar D, Blazar, Bruce R, Tolar, Jakub
Publicado 2016