The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling

por Cui, Yan, Groth, Susann, Troutman, Scott, Carlstedt, Annemarie, Sperka, Tobias, Riecken, Lars Björn, Kissil, Joseph L., Jin, Hongchuan, Morrison, Helen
Publicado 2019

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins

por Riecken, Lars Björn, Zoch, Ansgar, Wiehl, Ulrike, Reichert, Sabine, Scholl, Ingmar, Cui, Yan, Ziemer, Mirjana, Anderegg, Ulf, Hagel, Christian, Morrison, Helen
Publicado 2016

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

por Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Publicado 2021