Tumor Induced Stromal Reprogramming Drives Lymph Node Transformation

por Riedel, Angela, Shorthouse, David, Haas, Lisa, Hall, Benjamin A, Shields, Jacqueline
Publicado 2016

Time-Resolved scRNA-Seq Tracks the Adaptation of a Sensitive MCL Cell Line to Ibrutinib Treatment

por Fuhr, Viktoria, Vafadarnejad, Ehsan, Dietrich, Oliver, Arampatzi, Panagiota, Riedel, Angela, Saliba, Antoine-Emmanuel, Rosenwald, Andreas, Rauert-Wunderlich, Hilka
Publicado 2021

CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma

por Fuhr, Viktoria, Heidenreich, Shanice, Srivastava, Mugdha, Riedel, Angela, Düll, Johannes, Gerhard-Hartmann, Elena, Rosenwald, Andreas, Rauert-Wunderlich, Hilka
Publicado 2022

Exploring the role of stromal osmoregulation in cancer and disease using executable modelling

por Shorthouse, David, Riedel, Angela, Kerr, Emma, Pedro, Luisa, Bihary, Dóra, Samarajiwa, Shamith, Martins, Carla P., Shields, Jacqueline, Hall, Benjamin A.
Publicado 2018

Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth

por Davidson, Sarah, Efremova, Mirjana, Riedel, Angela, Mahata, Bidesh, Pramanik, Jhuma, Huuhtanen, Jani, Kar, Gozde, Vento-Tormo, Roser, Hagai, Tzachi, Chen, Xi, Haniffa, Muzlifah A., Shields, Jacqueline D., Teichmann, Sarah A.
Publicado 2020

Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

por Hongu, Tsunaki, Pein, Maren, Insua-Rodríguez, Jacob, Gutjahr, Ewgenija, Mattavelli, Greta, Meier, Jasmin, Decker, Kristin, Descot, Arnaud, Bozza, Matthias, Harbottle, Richard, Trumpp, Andreas, Sinn, Hans-Peter, Riedel, Angela, Oskarsson, Thordur
Publicado 2022

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs

por Pein, Maren, Insua-Rodríguez, Jacob, Hongu, Tsunaki, Riedel, Angela, Meier, Jasmin, Wiedmann, Lena, Decker, Kristin, Essers, Marieke A. G., Sinn, Hans-Peter, Spaich, Saskia, Sütterlin, Marc, Schneeweiss, Andreas, Trumpp, Andreas, Oskarsson, Thordur
Publicado 2020

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation

por Miragaia, Ricardo J., Gomes, Tomás, Chomka, Agnieszka, Jardine, Laura, Riedel, Angela, Hegazy, Ahmed N., Whibley, Natasha, Tucci, Andrea, Chen, Xi, Lindeman, Ida, Emerton, Guy, Krausgruber, Thomas, Shields, Jacqueline, Haniffa, Muzlifah, Powrie, Fiona, Teichmann, Sarah A.
Publicado 2019

Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma

por Riedel, Angela, Helal, Moutaz, Pedro, Luisa, Swietlik, Jonathan J., Shorthouse, David, Schmitz, Werner, Haas, Lisa, Young, Timothy, da Costa, Ana S.H., Davidson, Sarah, Bhandare, Pranjali, Wolf, Elmar, Hall, Benjamin A., Frezza, Christian, Oskarsson, Thordur, Shields, Jacqueline D.
Publicado 2022

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

por Mahata, Bidesh, Pramanik, Jhuma, van der Weyden, Louise, Polanski, Krzysztof, Kar, Gozde, Riedel, Angela, Chen, Xi, Fonseca, Nuno A., Kundu, Kousik, Campos, Lia S., Ryder, Edward, Duddy, Graham, Walczak, Izabela, Okkenhaug, Klaus, Adams, David J., Shields, Jacqueline D., Teichmann, Sarah A.
Publicado 2020

Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells

por Shaikh, Haroon, Pezoldt, Joern, Mokhtari, Zeinab, Gamboa Vargas, Juan, Le, Duc-Dung, Peña Mosca, Josefina, Arellano Viera, Estibaliz, Kern, Michael A.G., Graf, Caroline, Beyersdorf, Niklas, Lutz, Manfred B., Riedel, Angela, Büttner-Herold, Maike, Zernecke, Alma, Einsele, Hermann, Saliba, Antoine-Emmanuel, Ludewig, Burkhard, Huehn, Jochen, Beilhack, Andreas
Publicado 2022

High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to low-dose carfilzomib by co-in...

por Zhou, Xiang, Besse, Andrej, Peter, Jessica, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Xiao, Xianghui, Hornburger, Hannah, Haertle, Larissa, Mendez-Lopez, Max, Munawar, Umair, Riedel, Angela, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S., Florea, Bogdan, Einsele, Hermann, Kortüm, K. Martin, Driessen, Christoph, Besse, Lenka, Rasche, Leo
Publicado 2023

Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment

por Haake, Markus, Haack, Beatrice, Schäfer, Tina, Harter, Patrick N., Mattavelli, Greta, Eiring, Patrick, Vashist, Neha, Wedekink, Florian, Genssler, Sabrina, Fischer, Birgitt, Dahlhoff, Julia, Mokhtari, Fatemeh, Kuzkina, Anastasia, Welters, Marij J. P., Benz, Tamara M., Sorger, Lena, Thiemann, Vincent, Almanzar, Giovanni, Selle, Martina, Thein, Klara, Späth, Jacob, Gonzalez, Maria Cecilia, Reitinger, Carmen, Ipsen-Escobedo, Andrea, Wistuba-Hamprecht, Kilian, Eichler, Kristin, Filipski, Katharina, Zeiner, Pia S., Beschorner, Rudi, Goedemans, Renske, Gogolla, Falk Hagen, Hackl, Hubert, Rooswinkel, Rogier W., Thiem, Alexander, Roche, Paula Romer, Joshi, Hemant, Pühringer, Dirk, Wöckel, Achim, Diessner, Joachim E., Rüdiger, Manfred, Leo, Eugen, Cheng, Phil F., Levesque, Mitchell P., Goebeler, Matthias, Sauer, Markus, Nimmerjahn, Falk, Schuberth-Wagner, Christine, von Felten, Stefanie, Mittelbronn, Michel, Mehling, Matthias, Beilhack, Andreas, van der Burg, Sjoerd H., Riedel, Angela, Weide, Benjamin, Dummer, Reinhard, Wischhusen, Jörg
Publicado 2023