Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization Against PARP1 Inhibition in a Replication-Dependent Manner

por Rieckhoff, Johanna, Meyer, Felix, Classen, Sandra, Zielinski, Alexandra, Riepen, Britta, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin, Parplys, Ann Christin
Publicado 2020

Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

por Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Publicado 2016

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer

por Meyer, Felix, Becker, Saskia, Classen, Sandra, Parplys, Ann Christin, Mansour, Wael Yassin, Riepen, Britta, Timm, Sara, Ruebe, Claudia, Jasin, Maria, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin
Publicado 2020

G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

por Cetin, Meryem H., Rieckmann, Thorsten, Hoffer, Konstantin, Riepen, Britta, Christiansen, Sabrina, Gatzemeier, Fruzsina, Feyerabend, Simon, Schoof, Melanie, Schüller, Ulrich, Petersen, Cordula, Mynarek, Martin, Rothkamm, Kai, Kriegs, Malte, Struve, Nina
Publicado 2023

MEDB-50. Assessment of cellular radiosensitivity and DNA repair in medulloblastoma cell lines and patient-derivded xenograft slice cultures

por Feyerabend, Simon, Rieckmann, Thorsten, Riepen, Britta, Oetting, Agnes, Christiansen, Sabrina, Schoof, Melanie, Hardt, Annika, Köcher, Sabrina, Neumann, Julia, Schwarz, Rudolf, Mack, Norman, Schwalm, Benjamin, Federico, Aniello, Milde, Till, Kool, Marcel, Schüller, Ulrich, Rutkowski, Stefan, Petersen, Cordula, Rothkamm, Kai, Mynarek, Martin, Struve, Nina
Publicado 2022

Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities

por Struve, Nina, Hoffer, Konstantin, Weik, Anna-Sophie, Riepen, Britta, Krug, Leonie, Cetin, Meryem H, Burmester, Jasmin, Ott, Leonie, Liebing, Jana, Gatzemeier, Fruzsina, Müller-Goebel, Justus, Gerbach, Mirja, Bußmann, Lara, Parplys, Ann Christin, Unger, Kristian, Mansour, Wael Y, Schüller, Ulrich, Rieckmann, Thorsten, Petersen, Cordula, Rothkamm, Kai, Short, Susan C, Kriegs, Malte
Publicado 2021