Beyond the Cell Surface: Targeting Intracellular Negative Regulators to Enhance T cell Anti-Tumor Activity

por Sitaram, Poojitha, Uyemura, Bradley, Malarkannan, Subramaniam, Riese, Matthew J.
Publicado 2019

Uncoupling Therapeutic Efficacy from Immune-Related Adverse Events in Immune Checkpoint Blockade

por Hu, Weilei, Wang, Guosheng, Wang, Yian, Riese, Matthew J., You, Ming
Publicado 2020

Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road

por Wang, Liang-Chuan S, Riese, Matthew J, Moon, Edmund K, Albelda, Steven M
Publicado 2013

Novel role of platelet endothelial cell adhesion molecule-1 (PECAM-1) in facilitating TGF-beta-mediated inhibition of T cell function

por Newman, Debra, Adams, Tamara, Arumugam, Vidhyalakshmi, Bluemn, Theresa, Fu, Guoping, Riese, Matthew
Publicado 2015

Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer

por Riese, Matthew J., Moon, Edmund K., Johnson, Bryon D., Albelda, Steven M.
Publicado 2016

Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy

por Rajasekaran, Kamalakannan, Riese, Matthew J., Rao, Sridhar, Wang, Li, Thakar, Monica S., Sentman, Charles L., Malarkannan, Subramaniam
Publicado 2016

Adoptive cell therapy using PD-1(+) myeloma-reactive T cells eliminates established myeloma in mice

por Jing, Weiqing, Gershan, Jill A., Blitzer, Grace C., Palen, Katie, Weber, James, McOlash, Laura, Riese, Matthew, Johnson, Bryon D.
Publicado 2017

STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models

por Jing, Weiqing, McAllister, Donna, Vonderhaar, Emily P., Palen, Katie, Riese, Matthew J., Gershan, Jill, Johnson, Bryon D., Dwinell, Michael B.
Publicado 2019

Deletion of Cbl-b inhibits CD8(+) T-cell exhaustion and promotes CAR T-cell function

por Kumar, Jitendra, Kumar, Ritesh, Kumar Singh, Amir, Tsakem, Elviche L, Kathania, Mahesh, Riese, Matthew J, Theiss, Arianne L, Davila, Marco L, Venuprasad, K
Publicado 2021

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer

por Vonderhaar, Emily P., Barnekow, Nicholas S., McAllister, Donna, McOlash, Laura, Eid, Mahmoud Abu, Riese, Matthew J., Tarakanova, Vera L., Johnson, Bryon D., Dwinell, Michael B.
Publicado 2021

DGKζ exerts greater control than DGKα over CD8(+) T cell activity and tumor inhibition

por Gu, Junchen, Wang, Cindy, Cao, Carolyn, Huang, Jinwen, Holzhauer, Sandra, Desilva, Heshani, Wesley, Erin M., Evans, Douglas B., Benci, Joseph, Wichroski, Michael, Wee, Susan, Riese, Matthew J.
Publicado 2021

Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

por Gerbec, Zachary J., Hashemi, Elaheh, Nanbakhsh, Arash, Holzhauer, Sandra, Yang, Chao, Mei, Ao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J., Riese, Matthew J., Thakar, Monica S., Malarkannan, Subramaniam
Publicado 2020

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature

por Yang, Chao, Siebert, Jason R, Burns, Robert, Zheng, Yongwei, Mei, Ao, Bonacci, Benedetta, Wang, Demin, Urrutia, Raul A, Riese, Matthew J, Rao, Sridhar, Carlson, Karen-Sue, Thakar, Monica S, Malarkannan, Subramaniam
Publicado 2020

Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

por Yang, Chao, Siebert, Jason R., Burns, Robert, Gerbec, Zachary J., Bonacci, Benedetta, Rymaszewski, Amy, Rau, Mary, Riese, Matthew J., Rao, Sridhar, Carlson, Karen-Sue, Routes, John M., Verbsky, James W., Thakar, Monica S., Malarkannan, Subramaniam
Publicado 2019

Impact of Neoadjuvant Chemoradiation on Pathologic Response in Patients With Localized Pancreatic Cancer

por Wittmann, David, Hall, William A., Christians, Kathleen K., Barnes, Chad A., Jariwalla, Neil R., Aldakkak, Mohammed, Clarke, Callisia N., George, Ben, Ritch, Paul S., Riese, Matthew, Khan, Abdul H., Kulkarni, Naveen, Evans, John, Erickson, Beth A., Evans, Douglas B., Tsai, Susan
Publicado 2020

Academic Cancer Center Phase I Program Development

por Frankel, Arthur E., Flaherty, Keith T., Weiner, George J., Chen, Robert, Azad, Nilofer S., Pishvaian, Michael J., Thompson, John A., Taylor, Matthew H., Mahadevan, Daruka, Lockhart, A. Craig, Vaishampayan, Ulka N., Berlin, Jordan D., Smith, David C., Sarantopoulos, John, Riese, Matthew, Saleh, Mansoor N., Ahn, Chul, Frenkel, Eugene P.
Publicado 2017

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

por Bajor, David L., Mick, Rosemarie, Riese, Matthew J., Huang, Alex C., Sullivan, Brendan, Richman, Lee P., Torigian, Drew A., George, Sangeeth M., Stelekati, Erietta, Chen, Fang, Melenhorst, J. Joseph, Lacey, Simon F., Xu, Xiaowei, Wherry, E. John, Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Vonderheide, Robert H.
Publicado 2018