LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes

por Draber, Peter, Kupka, Sebastian, Reichert, Matthias, Draberova, Helena, Lafont, Elodie, de Miguel, Diego, Spilgies, Lisanne, Surinova, Silvia, Taraborrelli, Lucia, Hartwig, Torsten, Rieser, Eva, Martino, Luigi, Rittinger, Katrin, Walczak, Henning
Publicado 2015

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

por Lafont, Elodie, Draber, Peter, Rieser, Eva, Reichert, Matthias, Kupka, Sebastian, de Miguel, Diego, Draberova, Helena, von Mässenhausen, Anne, Bhamra, Amandeep, Henderson, Stephen, Wojdyla, Katarzyna, Chalk, Avigayil, Surinova, Silvia, Linkermann, Andreas, Walczak, Henning
Publicado 2018

­­LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation

por Zinngrebe, Julia, Rieser, Eva, Taraborrelli, Lucia, Peltzer, Nieves, Hartwig, Torsten, Ren, Hongwei, Kovács, Ildikó, Endres, Cornelia, Draber, Peter, Darding, Maurice, von Karstedt, Silvia, Lemke, Johannes, Dome, Balazs, Bergmann, Michael, Ferguson, Brian J., Walczak, Henning
Publicado 2016

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L

por Taraborrelli, Lucia, Peltzer, Nieves, Montinaro, Antonella, Kupka, Sebastian, Rieser, Eva, Hartwig, Torsten, Sarr, Aida, Darding, Maurice, Draber, Peter, Haas, Tobias L., Akarca, Ayse, Marafioti, Teresa, Pasparakis, Manolis, Bertin, John, Gough, Peter J., Bouillet, Philippe, Strasser, Andreas, Leverkus, Martin, Silke, John, Walczak, Henning
Publicado 2018

Compound heterozygous variants in OTULIN are associated with fulminant atypical late‐onset ORAS

por Zinngrebe, Julia, Moepps, Barbara, Monecke, Thomas, Gierschik, Peter, Schlichtig, Ferdinand, Barth, Thomas F E, Strauß, Gudrun, Boldrin, Elena, Posovszky, Carsten, Schulz, Ansgar, Beringer, Ortraud, Rieser, Eva, Jacobsen, Eva‐Maria, Lorenz, Myriam Ricarda, Schwarz, Klaus, Pannicke, Ulrich, Walczak, Henning, Niessing, Dierk, Schuetz, Catharina, Fischer‐Posovszky, Pamela, Debatin, Klaus‐Michael
Publicado 2022

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

por Teh, Charis E., Lalaoui, Najoua, Jain, Reema, Policheni, Antonia N., Heinlein, Melanie, Alvarez-Diaz, Silvia, Sheridan, Julie M., Rieser, Eva, Deuser, Stefanie, Darding, Maurice, Koay, Hui-Fern, Hu, Yifang, Kupresanin, Fiona, O'Reilly, Lorraine A., Godfrey, Dale I., Smyth, Gordon K., Bouillet, Philippe, Strasser, Andreas, Walczak, Henning, Silke, John, Gray, Daniel H. D.
Publicado 2016

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

por Peltzer, Nieves, Darding, Maurice, Montinaro, Antonella, Draber, Peter, Draberova, Helena, Kupka, Sebastian, Rieser, Eva, Fisher, Amanda, Hutchinson, Ciaran, Taraborrelli, Lucia, Hartwig, Torsten, Lafont, Elodie, Haas, Tobias L., Shimizu, Yutaka, Böiers, Charlotta, Sarr, Aida, Rickard, James, Alvarez-Diaz, Silvia, Ashworth, Michael T., Beal, Allison, Enver, Tariq, Bertin, John, Kaiser, William, Strasser, Andreas, Silke, John, Bouillet, Philippe, Walczak, Henning
Publicado 2018

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis

por Bolik, Julia, Krause, Freia, Stevanovic, Marija, Gandraß, Monja, Thomsen, Ilka, Schacht, Sarah-Sophie, Rieser, Eva, Müller, Miryam, Schumacher, Neele, Fritsch, Jürgen, Wichert, Rielana, Galun, Eithan, Bergmann, Juri, Röder, Christian, Schafmayer, Clemens, Egberts, Jan-Hendrik, Becker-Pauly, Christoph, Saftig, Paul, Lucius, Ralph, Schneider-Brachert, Wulf, Barikbin, Roja, Adam, Dieter, Voss, Matthias, Hitzl, Wolfgang, Krüger, Achim, Strilic, Boris, Sagi, Irit, Walczak, Henning, Rose-John, Stefan, Schmidt-Arras, Dirk
Publicado 2021