RNA degradation in antiviral immunity and autoimmunity

por Rigby, Rachel E., Rehwinkel, Jan
Publicado 2015

A versatile mouse model of COVID-19

por Borrmann, Helene, Rigby, Rachel E.
Publicado 2020

Deoxyguanosine is a TLR7 agonist

por Davenne, Tamara, Bridgeman, Anne, Rigby, Rachel E., Rehwinkel, Jan
Publicado 2019

SAMHD1-dependent retroviral control and escape in mice

por Rehwinkel, Jan, Maelfait, Jonathan, Rigby, Rachel, Bridgeman, Anne, Reis e Sousa, Caetano
Publicado 2013

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

por Rigby, Rachel E., Wise, Helen M., Smith, Nikki, Digard, Paul, Rehwinkel, Jan
Publicado 2019

Fractional response analysis reveals logarithmic cytokine responses in cellular populations

por Nienałtowski, Karol, Rigby, Rachel E., Walczak, Jarosław, Zakrzewska, Karolina E., Głów, Edyta, Rehwinkel, Jan, Komorowski, Michał
Publicado 2021

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses

por Tang, Qiannan, Rigby, Rachel E., Young, George R., Hvidt, Astrid Korning, Davis, Tanja, Tan, Tiong Kit, Bridgeman, Anne, Townsend, Alain R., Kassiotis, George, Rehwinkel, Jan
Publicado 2021

Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling

por Hertzog, Jonny, Dias Junior, Antonio Gregorio, Rigby, Rachel E., Donald, Claire L., Mayer, Alice, Sezgin, Erdinc, Song, Chaojun, Jin, Boquan, Hublitz, Philip, Eggeling, Christian, Kohl, Alain, Rehwinkel, Jan
Publicado 2018

SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

por Davenne, Tamara, Klintman, Jenny, Sharma, Sushma, Rigby, Rachel E., Blest, Henry T.W., Cursi, Chiara, Bridgeman, Anne, Dadonaite, Bernadeta, De Keersmaecker, Kim, Hillmen, Peter, Chabes, Andrei, Schuh, Anna, Rehwinkel, Jan
Publicado 2020

Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

por Hertzog, Jonny, Zhou, Wen, Fowler, Gerissa, Rigby, Rachel E, Bridgeman, Anne, Blest, Henry TW, Cursi, Chiara, Chauveau, Lise, Davenne, Tamara, Warner, Benjamin E, Kinchington, Paul R, Kranzusch, Philip J, Rehwinkel, Jan
Publicado 2022

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

por Rigby, Rachel E, Webb, Lauren M, Mackenzie, Karen J, Li, Yue, Leitch, Andrea, Reijns, Martin A M, Lundie, Rachel J, Revuelta, Ailsa, Davidson, Donald J, Diebold, Sandra, Modis, Yorgo, MacDonald, Andrew S, Jackson, Andrew P
Publicado 2014

Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response

por Mackenzie, Karen J, Carroll, Paula, Lettice, Laura, Tarnauskaitė, Žygimantė, Reddy, Kaalak, Dix, Flora, Revuelta, Ailsa, Abbondati, Erika, Rigby, Rachel E, Rabe, Björn, Kilanowski, Fiona, Grimes, Graeme, Fluteau, Adeline, Devenney, Paul S, Hill, Robert E, Reijns, Martin AM, Jackson, Andrew P
Publicado 2016

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

por Reijns, Martin A.M., Rabe, Björn, Rigby, Rachel E., Mill, Pleasantine, Astell, Katy R., Lettice, Laura A., Boyle, Shelagh, Leitch, Andrea, Keighren, Margaret, Kilanowski, Fiona, Devenney, Paul S., Sexton, David, Grimes, Graeme, Holt, Ian J., Hill, Robert E., Taylor, Martin S., Lawson, Kirstie A., Dorin, Julia R., Jackson, Andrew P.
Publicado 2012

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

por Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M. D., Hardman, Clare S., Alham, Nasullah K., Rigby, Rachel E., Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Publicado 2021

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

por Hansen, Anne Louise, Buchan, Gregory J., Rühl, Michael, Mukai, Kojiro, Salvatore, Sonia R., Ogawa, Emari, Andersen, Sidsel D., Iversen, Marie B., Thielke, Anne L., Gunderstofte, Camilla, Motwani, Mona, Møller, Charlotte T., Jakobsen, Andreas S., Fitzgerald, Katherine A., Roos, Jessica, Lin, Rongtuan, Maier, Thorsten J., Goldbach-Mansky, Raphaela, Miner, Cathrine A., Qian, Wei, Miner, Jonathan J., Rigby, Rachel E., Rehwinkel, Jan, Jakobsen, Martin R., Arai, Hiroyuki, Taguchi, Tomohiko, Schopfer, Francisco J., Olagnier, David, Holm, Christian K.
Publicado 2018