Incorporation of Cobalt‐Cyclen Complexes into Templated Nanogels Results in Enhanced Activity

por Jorge, Ana Rita, Chernobryva, Mariya, Rigby, Stephen E. J., Watkinson, Michael, Resmini, Marina
Publicado 2015

A Conformational Sampling Model for Radical Catalysis in Pyridoxal Phosphate- and Cobalamin-dependent Enzymes

por Menon, Binuraj R. K., Fisher, Karl, Rigby, Stephen E. J., Scrutton, Nigel S., Leys, David
Publicado 2014

Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope

por Halliwell, Tom, Fisher, Karl, Payne, Karl A. P., Rigby, Stephen E. J., Leys, David
Publicado 2020

Heterologous expression of cobalamin dependent class-III enzymes

por Halliwell, Tom, Fisher, Karl, Payne, Karl A.P., Rigby, Stephen E.J., Leys, David
Publicado 2021

Glutamate 338 is an electrostatic facilitator of C–Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase

por Menon, Binuraj R K, Menon, Navya, Fisher, Karl, Rigby, Stephen E J, Leys, David, Scrutton, Nigel S
Publicado 2015

Efficient NADPH-dependent dehalogenation afforded by a self-sufficient reductive dehalogenase

por Fisher, Karl, Halliwell, Tom, Payne, Karl A.P., Ragala, Gabriel, Hay, Sam, Rigby, Stephen E.J., Leys, David
Publicado 2023

Characterisation of PduS, the pdu Metabolosome Corrin Reductase, and Evidence of Substructural Organisation within the Bacterial Microcompartment

por Parsons, Joshua B., Lawrence, Andrew D., McLean, Kirsty J., Munro, Andrew W., Rigby, Stephen E. J., Warren, Martin J.
Publicado 2010

Ultrafast Red Light Activation of Synechocystis Phytochrome Cph1 Triggers Major Structural Change to Form the Pfr Signalling-Competent State

por Heyes, Derren J., Khara, Basile, Sakuma, Michiyo, Hardman, Samantha J. O., O'Cualain, Ronan, Rigby, Stephen E. J., Scrutton, Nigel S.
Publicado 2012

Energy Landscapes and Catalysis in Nitric-oxide Synthase

por Sobolewska-Stawiarz, Anna, Leferink, Nicole G. H., Fisher, Karl, Heyes, Derren J., Hay, Sam, Rigby, Stephen E. J., Scrutton, Nigel S.
Publicado 2014

The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry

por Marshall, Stephen A., Payne, Karl A. P., Fisher, Karl, White, Mark D., Ní Cheallaigh, Aisling, Balaikaite, Arune, Rigby, Stephen E. J., Leys, David
Publicado 2019

Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

por Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
Publicado 2015

The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis

por Bailey, Samuel S., Payne, Karl A. P., Fisher, Karl, Marshall, Stephen A., Cliff, Matthew J., Spiess, Reynard, Parker, David A., Rigby, Stephen E. J., Leys, David
Publicado 2018

Use of a Molecular Decoy to Segregate Transport from Antigenicity in the FrpB Iron Transporter from Neisseria meningitidis

por Saleem, Muhammad, Prince, Stephen M., Rigby, Stephen E. J., Imran, Muhammad, Patel, Hema, Chan, Hannah, Sanders, Holly, Maiden, Martin C. J., Feavers, Ian M., Derrick, Jeremy P.
Publicado 2013

Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence

por Payne, Karl A. P., Marshall, Stephen A., Fisher, Karl, Rigby, Stephen E. J., Cliff, Matthew J., Spiess, Reynard, Cannas, Diego M., Larrosa, Igor, Hay, Sam, Leys, David
Publicado 2021

Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

por Baker, George J., Girvan, Hazel M., Matthews, Sarah, McLean, Kirsty J., Golovanova, Marina, Waltham, Timothy N., Rigby, Stephen E. J., Nelson, David R., Blankley, Richard T., Munro, Andrew W.
Publicado 2017

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR)

por Lawrence, Andrew D., Taylor, Samantha L., Scott, Alan, Rowe, Michelle L., Johnson, Christopher M., Rigby, Stephen E. J., Geeves, Michael A., Pickersgill, Richard W., Howard, Mark J., Warren, Martin J.
Publicado 2014

Bacillus megaterium Has Both a Functional BluB Protein Required for DMB Synthesis and a Related Flavoprotein That Forms a Stable Radical Species

por Collins, Hannah F., Biedendieck, Rebekka, Leech, Helen K., Gray, Michael, Escalante-Semerena, Jorge C., McLean, Kirsty J., Munro, Andrew W., Rigby, Stephen E. J., Warren, Martin J., Lawrence, Andrew D.
Publicado 2013

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleT(JE)

por Matthews, Sarah, Belcher, James D., Tee, Kang Lan, Girvan, Hazel M., McLean, Kirsty J., Rigby, Stephen E. J., Levy, Colin W., Leys, David, Parker, David A., Blankley, Richard T., Munro, Andrew W.
Publicado 2017

A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase

por Ortmayer, Mary, Hardy, Florence J., Quesne, Matthew G., Fisher, Karl, Levy, Colin, Heyes, Derren J., Catlow, C. Richard A., de Visser, Sam P., Rigby, Stephen E. J., Hay, Sam, Green, Anthony P.
Publicado 2021

UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis

por White, Mark D., Payne, Karl A.P., Fisher, Karl, Marshall, Stephen A., Parker, David, Rattray, Nicholas J.W., Trivedi, Drupad K., Goodacre, Royston, Rigby, Stephen E.J., Scrutton, Nigel S., Hay, Sam, Leys, David
Publicado 2015