Real-World Perspectives and Practices for Pneumonitis/Interstitial Lung Disease Associated With Trastuzumab Deruxtecan Use in Human Epidermal Growth Factor Receptor 2–Expressing Me...

por Rugo, Hope S., Crossno, Christine L., Gesthalter, Yaron B., Kelley, Kristen, Moore, Heather B., Rimawi, Mothaffar F., Westbrook, Kelly E., Buys, Saundra S.
Publicado 2023

Lumpectomy followed by radiation improves survival in HER2 positive and triple‐negative breast cancer with high tumor‐infiltrating lymphocytes compared to mastectomy alone

por Mouabbi, Jason A., Chand, Momal, Asghar, Ishaq A., Sakhi, Ramen, Ockner, Daniel, Dul, Carrie L., Hadid, Tarik, Aref, Amr, Rimawi, Mothaffar F., Hoyos, Valentina
Publicado 2021

β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib

por Huang, Catherine, Park, Catherine C, Hilsenbeck, Susan G, Ward, Robin, Rimawi, Mothaffar F, Wang, Yen-chao, Shou, Jiang, Bissell, Mina J, Osborne, C Kent, Schiff, Rachel
Publicado 2011

Pertuzumab, Trastuzumab, and an Aromatase Inhibitor for HER2-Positive and Hormone Receptor–Positive Metastatic or Locally Advanced Breast Cancer: PERTAIN Final Analysis

por Arpino, Grazia, de la Haba Rodríguez, Juan, Ferrero, Jean-Marc, De Placido, Sabino, Osborne, C. Kent, Klingbiel, Dirk, Revelant, Valentine, Wohlfarth, Christine, Poppe, Raf, Rimawi, Mothaffar F.
Publicado 2023

Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins

por Wang, Junkai, Saltzman, Alexander B., Jaehnig, Eric J., Lei, Jonathan T., Malovannaya, Anna, Holt, Matthew V., Young, Meggie N., Rimawi, Mothaffar F., Ademuyiwa, Foluso O., Anurag, Meenakshi, Kim, Beom-Jun, Ellis, Matthew J.
Publicado 2023

Different mechanisms for resistance to trastuzumab versus lapatinib in HER2- positive breast cancers -- role of estrogen receptor and HER2 reactivation

por Wang, Yen-Chao, Morrison, Gladys, Gillihan, Ryan, Guo, Jun, Ward, Robin M, Fu, Xiaoyong, Botero, Maria F, Healy, Nuala A, Hilsenbeck, Susan G, Phillips, Gail Lewis, Chamness, Gary C, Rimawi, Mothaffar F, Osborne, C Kent, Schiff, Rachel
Publicado 2011

Biomarkers of Response and Resistance to Palbociclib Plus Letrozole in Patients With ER(+)/HER2(−) Breast Cancer

por Dowsett, Mitch, Kilburn, Lucy, Rimawi, Mothaffar F., Osborne, C. Kent, Pogue-Geile, Katherine, Liu, Yuan, Jacobs, Samuel A., Finnigan, Melanie, Puhalla, Shannon, Dodson, Andrew, Martins, Vera, Cheang, Maggie, Perry, Sophie, Holcombe, Chris, Turner, Nick, Swift, Claire, Bliss, Judith M., Johnston, Stephen
Publicado 2022

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

por Nardone, Agostina, Weir, Hazel, Delpuech, Oona, Brown, Henry, De Angelis, Carmine, Cataldo, Maria Letizia, Fu, Xiaoyong, Shea, Martin J., Mitchell, Tamika, Veeraraghavan, Jamunarani, Nagi, Chandandeep, Pilling, Mark, Rimawi, Mothaffar F., Trivedi, Meghana, Hilsenbeck, Susan G., Chamness, Gary C., Jeselsohn, Rinath, Osborne, C. Kent, Schiff, Rachel
Publicado 2018

Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models

por Veeraraghavan, Jamunarani, Gutierrez, Carolina, Sethunath, Vidyalakshmi, Mehravaran, Sepideh, Giuliano, Mario, Shea, Martin J., Mitchell, Tamika, Wang, Tao, Nanda, Sarmistha, Pereira, Resel, Davis, Robert, Goutsouliak, Kristina, Qin, Lanfang, De Angelis, Carmine, Diala, Irmina, Lalani, Alshad S., Nagi, Chandandeep, Hilsenbeck, Susan G., Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel
Publicado 2021

Endocrine-Based Treatments in Clinically-Relevant Subgroups of Hormone Receptor-Positive/HER2-Negative Metastatic Breast Cancer: Systematic Review and Meta-Analysis

por Schettini, Francesco, Giuliano, Mario, Giudici, Fabiola, Conte, Benedetta, De Placido, Pietro, Venturini, Sergio, Rognoni, Carla, Di Leo, Angelo, Locci, Mariavittoria, Jerusalem, Guy, Del Mastro, Lucia, Puglisi, Fabio, Conte, PierFranco, De Laurentiis, Michelino, Pusztai, Lajos, Rimawi, Mothaffar F., Schiff, Rachel, Arpino, Grazia, De Placido, Sabino, Prat, Aleix, Generali, Daniele
Publicado 2021

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

por Giuliano, Mario, Herrera, Sabrina, Christiny, Pavel, Shaw, Chad, Creighton, Chad J, Mitchell, Tamika, Bhat, Raksha, Zhang, Xiaomei, Mao, Sufeng, Dobrolecki, Lacey E, Al-rawi, Ahmed, Chen, Fengju, Veneziani, Bianca M, Zhang, Xiang H-F, Hilsenbeck, Susan G, Contreras, Alejandro, Gutierrez, Carolina, Jeselsohn, Rinath M, Rimawi, Mothaffar F, Osborne, C Kent, Lewis, Michael T, Schiff, Rachel, Trivedi, Meghana V
Publicado 2015

Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030

por Parsons, Heather A., Blewett, Timothy, Chu, Xiangying, Sridhar, Sainetra, Santos, Katheryn, Xiong, Kan, Abramson, Vandana G., Patel, Ashka, Cheng, Ju, Brufsky, Adam, Rhoades, Justin, Force, Jeremy, Liu, Ruolin, Traina, Tiffany A., Carey, Lisa A., Rimawi, Mothaffar F., Miller, Kathy D., Stearns, Vered, Specht, Jennifer, Falkson, Carla, Burstein, Harold J., Wolff, Antonio C., Winer, Eric P., Tayob, Nabihah, Krop, Ian E., Makrigiorgos, G. Mike, Golub, Todd R., Mayer, Erica L., Adalsteinsson, Viktor A.
Publicado 2023

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-a...

por Fu, Xiaoyong, Creighton, Chad J, Biswal, Nrusingh C, Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Gladys, Nardone, Agostina, Karlin, Kristen L, Westbrook, Thomas F, Heiser, Laura M, Anur, Pavana, Spellman, Paul, Guichard, Sylvie M, Smith, Paul D, Davies, Barry R, Klinowska, Teresa, Lee, Adrian V, Mills, Gordon B, Rimawi, Mothaffar F, Hilsenbeck, Susan G, Gray, Joe W, Joshi, Amit, Osborne, C Kent, Schiff, Rachel
Publicado 2014

Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach

por Petrosyan, Varduhi, Dobrolecki, Lacey E., Thistlethwaite, Lillian, Lewis, Alaina N., Sallas, Christina, Srinivasan, Ramakrishnan R., Lei, Jonathan T., Kovacevic, Vladimir, Obradovic, Predrag, Ellis, Matthew J., Osborne, C. Kent, Rimawi, Mothaffar F., Pavlick, Anne, Shafaee, Maryam Nemati, Dowst, Heidi, Jain, Antrix, Saltzman, Alexander B., Malovannaya, Anna, Marangoni, Elisabetta, Welm, Alana L., Welm, Bryan E., Li, Shunqiang, Wulf, Gerburg M., Sonzogni, Olmo, Huang, Chen, Vasaikar, Suhas, Hilsenbeck, Susan G., Zhang, Bing, Milosavljevic, Aleksandar, Lewis, Michael T.
Publicado 2022

Microscaled proteogenomic methods for precision oncology

por Satpathy, Shankha, Jaehnig, Eric J., Krug, Karsten, Kim, Beom-Jun, Saltzman, Alexander B., Chan, Doug W., Holloway, Kimberly R., Anurag, Meenakshi, Huang, Chen, Singh, Purba, Gao, Ari, Namai, Noel, Dou, Yongchao, Wen, Bo, Vasaikar, Suhas V., Mutch, David, Watson, Mark A., Ma, Cynthia, Ademuyiwa, Foluso O., Rimawi, Mothaffar F., Schiff, Rachel, Hoog, Jeremy, Jacobs, Samuel, Malovannaya, Anna, Hyslop, Terry, Clauser, Karl R., Mani, D. R., Perou, Charles M., Miles, George, Zhang, Bing, Gillette, Michael A., Carr, Steven A., Ellis, Matthew J.
Publicado 2020

TBCRC 022: A Phase II Trial of Neratinib and Capecitabine for Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases

por Freedman, Rachel A., Gelman, Rebecca S., Anders, Carey K., Melisko, Michelle E., Parsons, Heather A., Cropp, Anne M., Silvestri, Kelly, Cotter, Christine M., Componeschi, Kathryn P., Marte, Juan M., Connolly, Roisin M., Moy, Beverly, Van Poznak, Catherine H., Blackwell, Kimberly L., Puhalla, Shannon L., Jankowitz, Rachel C., Smith, Karen L., Ibrahim, Nuhad, Moynihan, Timothy J., O’Sullivan, Ciara C., Nangia, Julie, Niravath, Polly, Tung, Nadine, Pohlmann, Paula R., Burns, Robyn, Rimawi, Mothaffar F., Krop, Ian E., Wolff, Antonio C., Winer, Eric P., Lin, Nancy U.
Publicado 2019

Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer

por Anurag, Meenakshi, Jaehnig, Eric J., Krug, Karsten, Lei, Jonathan T., Bergstrom, Erik J., Kim, Beom-Jun, Vashist, Tanmayi D., Huynh, Anh Minh Tran, Dou, Yongchao, Gou, Xuxu, Huang, Chen, Shi, Zhiao, Wen, Bo, Korchina, Viktoriya, Gibbs, Richard A., Muzny, Donna M., Doddapaneni, Harshavardhan, Dobrolecki, Lacey E., Rodriguez, Henry, Robles, Ana I., Hiltke, Tara, Lewis, Michael T., Nangia, Julie R., Nemati Shafaee, Maryam, Li, Shunqiang, Hagemann, Ian S., Hoog, Jeremy, Lim, Bora, Osborne, C. Kent, Mani, D.R., Gillette, Michael A., Zhang, Bing, Echeverria, Gloria V., Miles, George, Rimawi, Mothaffar F., Carr, Steven A., Ademuyiwa, Foluso O., Satpathy, Shankha, Ellis, Matthew J.
Publicado 2022

Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis

por Garcia-Recio, Susana, Hinoue, Toshinori, Wheeler, Gregory L., Kelly, Benjamin J., Garrido-Castro, Ana C., Pascual, Tomas, De Cubas, Aguirre A., Xia, Youli, Felsheim, Brooke M., McClure, Marni B., Rajkovic, Andrei, Karaesmen, Ezgi, Smith, Markia A., Fan, Cheng, Ericsson, Paula I. Gonzalez, Sanders, Melinda E., Creighton, Chad J., Bowen, Jay, Leraas, Kristen, Burns, Robyn T., Coppens, Sara, Wheless, Amy, Rezk, Salma, Garrett, Amy L., Parker, Joel S., Foy, Kelly K., Shen, Hui, Park, Ben H., Krop, Ian, Anders, Carey, Gastier-Foster, Julie, Rimawi, Mothaffar F., Nanda, Rita, Lin, Nancy U., Isaacs, Claudine, Marcom, P. Kelly, Storniolo, Anna Maria, Couch, Fergus J., Chandran, Uma, Davis, Michael, Silverstein, Jonathan, Ropelewski, Alexander, Liu, Minetta C., Hilsenbeck, Susan G., Norton, Larry, Richardson, Andrea L., Symmans, W. Fraser, Wolff, Antonio C., Davidson, Nancy E., Carey, Lisa A., Lee, Adrian V., Balko, Justin M., Hoadley, Katherine A., Laird, Peter W., Mardis, Elaine R., King, Tari A., Perou, Charles M.
Publicado 2022