CD47-blocking therapies stimulate macrophage cytokine secretion and are effective in a model of peritoneal carcinomatosis

por Weiskopf, Kipp, Ring, Aaron, Garcia, K Christopher, Weissman, Irving
Publicado 2015

Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2

por Sitrin, Jonathan, Ring, Aaron, Garcia, K. Christopher, Benoist, Christophe, Mathis, Diane
Publicado 2013

A modified IL-18 drug in combination with CTLA-4 blockade enhances anti-tumor efficacy in preclinical models of renal cell carcinoma

por Schoenfeld, David, Djureinovic, Dijana, Zhang, Lin, Mann, Jacqueline, Huck, John, Jilaveanu, Lucia, Ring, Aaron, Kluger, Harriet
Publicado 2023

Developing synthetic tools to decipher the tumor–immune interactome

por Weizman, Orr-El, Luyten, Sophia, Lu, Peiwen, Song, Eric, Qin, Kai, Mostaghimi, Darius, Ring, Aaron M., Iwasaki, Akiko
Publicado 2023

Adrenaline-activated structure of the β(2)-adrenoceptor stabilized by an engineered nanobody

por Ring, Aaron M., Manglik, Aashish, Kruse, Andrew C., Enos, Michael D., Weis, William I., Garcia, K. Christopher, Kobilka, Brian K.
Publicado 2013

Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants

por Weiskopf, Kipp, Ring, Aaron M, Schnorr, Peter J, Volkmer, Jens-Peter, Volkmer, Anne Kathrin, Weissman, Irving L, Garcia, K Christopher
Publicado 2013

WNK2 Kinase Is a Novel Regulator of Essential Neuronal Cation-Chloride Cotransporters

por Rinehart, Jesse, Vázquez, Norma, Kahle, Kristopher T., Hodson, Caleb A., Ring, Aaron M., Gulcicek, Erol E., Louvi, Angeliki, Bobadilla, Norma A., Gamba, Gerardo, Lifton, Richard P.
Publicado 2011

Newborn Dried Blood Spots for Serologic Surveys of COVID-19

por Liu, Feimei, Nguyen, Mytien, Vijayakumar, Pavithra, Kaplan, Alanna, Meir, Amit, Dai, Yile, Wang, Eric, Walsh, Hannah, Ring, Aaron M., Omer, Saad B., Farhadian, Shelli F.
Publicado 2020

CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever

por Arora, Gunjan, Lynn, Geoffrey E., Tang, Xiaotian, Rosen, Connor E., Hoornstra, Dieuwertje, Sajid, Andaleeb, Hovius, Joppe W., Palm, Noah W., Ring, Aaron M., Fikrig, Erol
Publicado 2022

IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

por Clark, Joseph T., Weizman, Orr-El, Aldridge, Daniel L., Shallberg, Lindsey A., Eberhard, Julia, Lanzar, Zachary, Wasche, Devon, Huck, John D., Zhou, Ting, Ring, Aaron M., Hunter, Christopher A.
Publicado 2023

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

por Israelow, Benjamin, Song, Eric, Mao, Tianyang, Lu, Peiwen, Meir, Amit, Liu, Feimei, Alfajaro, Mia Madel, Wei, Jin, Dong, Huiping, Homer, Robert J, Ring, Aaron, Wilen, Craig B, Iwasaki, Akiko
Publicado 2020

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

por Israelow, Benjamin, Song, Eric, Mao, Tianyang, Lu, Peiwen, Meir, Amit, Liu, Feimei, Alfajaro, Mia Madel, Wei, Jin, Dong, Huiping, Homer, Robert J., Ring, Aaron, Wilen, Craig B., Iwasaki, Akiko
Publicado 2020

Mechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15

por Ring, Aaron M., Lin, Jian-Xin, Feng, Dan, Mitra, Suman, Rickert, Mathias, Bowman, Gregory R., Pande, Vijay S., Li, Peng, Moraga, Ignacio, Spolski, Rosanne, Özkan, Engin, Leonard, Warren J., Garcia, K. Christopher
Publicado 2012

Yeast surface display platform for rapid discovery of conformationally selective nanobodies

por McMahon, Conor, Baier, Alexander S., Pascolutti, Roberta, Wegrecki, Marcin, Zheng, Sanduo, Ong, Janice X., Erlandson, Sarah C., Hilger, Daniel, Rasmussen, Søren G. F., Ring, Aaron M., Manglik, Aashish, Kruse, Andrew C.
Publicado 2018

The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6

por Sateriale, Adam, Gullicksrud, Jodi A., Engiles, Julie B., McLeod, Briana I., Kugler, Emily M., Henao-Mejia, Jorge, Zhou, Ting, Ring, Aaron M., Brodsky, Igor E., Hunter, Christopher A., Striepen, Boris
Publicado 2021

An Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector

por Cao, Yongguo, Rosen, Connor, Arora, Gunjan, Gupta, Akash, Booth, Carmen J., Murfin, Kristen E., Cerny, Jiri, Marin Lopez, Alejandro, Chuang, Yu-Min, Tang, Xiaotian, Pal, Utpal, Ring, Aaron, Narasimhan, Sukanya, Fikrig, Erol
Publicado 2020

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade

por Anderson, Katie L., Snyder, Kristin M., Ito, Daisuke, Lins, Debra C., Mills, Lauren J., Weiskopf, Kipp, Ring, Nan G., Ring, Aaron M., Shimizu, Yoji, Mescher, Matthew F., Weissman, Irving L., Modiano, Jaime F.
Publicado 2020

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy

por Zhou, Ting, Damsky, William, Weizman, Orr-El, McGeary, Meaghan K., Hartmann, K. Patricia, Rosen, Connor E., Fischer, Suzanne, Jackson, Ruaidhri, Flavell, Richard A., Wang, Jun, Sanmamed, Miguel F., Bosenberg, Marcus W., Ring, Aaron M.
Publicado 2020

Exploiting a natural conformational switch to engineer an Interleukin-2 superkine

por Levin, Aron M., Bates, Darren L., Ring, Aaron M., Krieg, Carsten, Lin, Jack T., Su, Leon, Moraga, Ignacio L., Raeber, Miro E., Bowman, Gregory R., Novick, Paul, Pande, Vijay S., Fathman, C. Garrison, Boyman, Onur, Garcia, K. Christopher
Publicado 2012

PD-1 expression by tumor-associated macrophages inhibits phagocytosis and tumor immunity

por Gordon, Sydney R., Maute, Roy L., Dulken, Ben W., Hutter, Gregor, George, Benson M., McCracken, Melissa N., Gupta, Rohit, Tsai, Jonathan M., Sinha, Rahul, Corey, Daniel, Ring, Aaron M., Connolly, Andrew J., Weissman, Irving L.
Publicado 2017