PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology

por Rinne, Sara S., Orlova, Anna, Tolmachev, Vladimir
Publicado 2021

(66)Ga-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [(66)Ga]Ga-NOTA-PEG(2)-RM26

por Rinne, Sara S., Abouzayed, Ayman, Gagnon, Katherine, Tolmachev, Vladimir, Orlova, Anna
Publicado 2021

On the prevention of kidney uptake of radiolabeled DARPins

por Altai, Mohamed, Garousi, Javad, Rinne, Sara S., Schulga, Alexey, Deyev, Sergey, Vorobyeva, Anzhelika
Publicado 2020

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

por Lundmark, Fanny, Olanders, Gustav, Rinne, Sara Sophie, Abouzayed, Ayman, Orlova, Anna, Rosenström, Ulrika
Publicado 2022

Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

por Vorobyeva, Anzhelika, Schulga, Alexey, Rinne, Sara S., Günther, Tyran, Orlova, Anna, Deyev, Sergey, Tolmachev, Vladimir
Publicado 2019

Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody–DM1 Drug Conjugates

por Ding, Haozhong, Altai, Mohamed, Rinne, Sara S., Vorobyeva, Anzhelika, Tolmachev, Vladimir, Gräslund, Torbjörn, Orlova, Anna
Publicado 2019

Preclinical Evaluation of (99m)Tc-Labeled GRPR Antagonists maSSS/SES-PEG(2)-RM26 for Imaging of Prostate Cancer

por Abouzayed, Ayman, Rinne, Sara S., Sabahnoo, Hamideh, Sörensen, Jens, Chernov, Vladimir, Tolmachev, Vladimir, Orlova, Anna
Publicado 2021

Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

por Vorobyeva, Anzhelika, Oroujeni, Maryam, Lindbo, Sarah, Hober, Sophia, Xu, Tianqi, Liu, Yongsheng, Rinne, Sara S., Garousi, Javad
Publicado 2020

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

por Abouzayed, Ayman, Yim, Cheng-Bin, Mitran, Bogdan, Rinne, Sara S., Tolmachev, Vladimir, Larhed, Mats, Rosenström, Ulrika, Orlova, Anna
Publicado 2019

Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

por Mitran, Bogdan, Thisgaard, Helge, Rinne, Sara, Dam, Johan Hygum, Azami, Frishta, Tolmachev, Vladimir, Orlova, Anna, Rosenström, Ulrika
Publicado 2019

Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

por Rinne, Sara S., Xu, Tianqi, Dahlsson Leitao, Charles, Ståhl, Stefan, Löfblom, John, Orlova, Anna, Tolmachev, Vladimir, Vorobyeva, Anzhelika
Publicado 2020

HER3 PET Imaging: (68)Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to (89)Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

por Rinne, Sara S., Leitao, Charles Dahlsson, Abouzayed, Ayman, Vorobyeva, Anzhelika, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Publicado 2021

Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

por Rinne, Sara S., Dahlsson Leitao, Charles, Saleh-nihad, Zahra, Mitran, Bogdan, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Publicado 2020

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer—Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

por Lundmark, Fanny, Abouzayed, Ayman, Mitran, Bogdan, Rinne, Sara S., Varasteh, Zohreh, Larhed, Mats, Tolmachev, Vladimir, Rosenström, Ulrika, Orlova, Anna
Publicado 2020

Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

por Baun, Christina, Mitran, Bogdan, Rinne, Sara S., Dam, Johan H., Olsen, Birgitte B., Tolmachev, Vladimir, Orlova, Anna, Thisgaard, Helge
Publicado 2020

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy

por Vorobyeva, Anzhelika, Westerlund, Kristina, Mitran, Bogdan, Altai, Mohamed, Rinne, Sara, Sörensen, Jens, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson
Publicado 2018

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

por Altai, Mohamed, Leitao, Charles Dahlsson, Rinne, Sara S., Vorobyeva, Anzhelika, Atterby, Christina, Ståhl, Stefan, Tolmachev, Vladimir, Löfblom, John, Orlova, Anna
Publicado 2018

Increase in negative charge of (68)Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

por Rinne, Sara S., Dahlsson Leitao, Charles, Gentry, Joshua, Mitran, Bogdan, Abouzayed, Ayman, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Publicado 2019

Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of (68)Ga-Labeled Tracers

por Dahlsson Leitao, Charles, Rinne, Sara S., Mitran, Bogdan, Vorobyeva, Anzhelika, Andersson, Ken G., Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Publicado 2019

Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

por Vorobyeva, Anzhelika, Konovalova, Elena, Xu, Tianqi, Schulga, Alexey, Altai, Mohamed, Garousi, Javad, Rinne, Sara S., Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey
Publicado 2020