Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay

por Risse, Emmanuel, Nicoll, Andrew J., Taylor, William A., Wright, Daniel, Badoni, Mayank, Yang, Xiaofan, Farrow, Mark A., Collinge, John
Publicado 2015

Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis

por Smethurst, Phillip, Risse, Emmanuel, Tyzack, Giulia E, Mitchell, Jamie S, Taha, Doaa M, Chen, Yun-Ru, Newcombe, Jia, Collinge, John, Sidle, Katie, Patani, Rickie
Publicado 2020

Highly infectious prions are not directly neurotoxic

por Benilova, Iryna, Reilly, Madeleine, Terry, Cassandra, Wenborn, Adam, Schmidt, Christian, Marinho, Aline T., Risse, Emmanuel, Al-Doujaily, Huda, Wiggins De Oliveira, Michael, Sandberg, Malin K., Wadsworth, Jonathan D. F., Jat, Parmjit S., Collinge, John
Publicado 2020

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

por Nicoll, Andrew J., Panico, Silvia, Freir, Darragh B., Wright, Daniel, Terry, Cassandra, Risse, Emmanuel, Herron, Caroline E., O’Malley, Tiernan, Wadsworth, Jonathan D. F., Farrow, Mark A., Walsh, Dominic M., Saibil, Helen R., Collinge, John
Publicado 2013

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

por Freir, Darragh B., Nicoll, Andrew J., Klyubin, Igor, Panico, Silvia, Mc Donald, Jessica M., Risse, Emmanuel, Asante, Emmanuel A., Farrow, Mark A., Sessions, Richard B., Saibil, Helen R., Clarke, Anthony R., Rowan, Michael J., Walsh, Dominic M., Collinge, John
Publicado 2011

N-terminal Domain of Prion Protein Directs Its Oligomeric Association

por Trevitt, Clare R., Hosszu, Laszlo L. P., Batchelor, Mark, Panico, Silvia, Terry, Cassandra, Nicoll, Andrew J., Risse, Emmanuel, Taylor, William A., Sandberg, Malin K., Al-Doujaily, Huda, Linehan, Jacqueline M., Saibil, Helen R., Scott, David J., Collinge, John, Waltho, Jonathan P., Clarke, Anthony R.
Publicado 2014