Spotlight Commentary: How to prove pharmacology of immunomodulatory drugs in a phase 1 trial?

por Rissmann, Robert, Szabadi, Elemer
Publicado 2019

Commentary on “Investigator brochures for phase I/II trials lack information on the robustness of preclinical safety studies” by Sievers et al.

por Rissmann, Robert, Zuiker, Rob
Publicado 2021

Anti‐interleukin‐17A for pityriasis rubra pilaris: catching the psoriasis biologic wave

por Balak, Deepak M.W., Rissmann, Robert
Publicado 2022

Under‐representation of elderly in clinical trials: An analysis of the initial approval documents in the Food and Drug Administration database

por Ruiter, Rikje, Burggraaf, Jacobus, Rissmann, Robert
Publicado 2019

Sofosbuvir and daclatasvir

por Hessel, Marleen H. M., Cohen, Adam F., Rissmann, Robert
Publicado 2016

Blueprint for mechanistic, data‐rich early phase clinical pharmacology studies in dermatology

por Rissmann, Robert, Moerland, Matthijs, van Doorn, Martijn B.A.
Publicado 2020

Gender differences in clinical registration trials: is there a real problem?

por Labots, Geert, Jones, Aubrey, de Visser, Saco J., Rissmann, Robert, Burggraaf, Jacobus
Publicado 2018

Skin barrier disruption by acetone: observations in a hairless mouse skin model

por Rissmann, Robert, Oudshoorn, Marion H. M., Hennink, Wim E., Ponec, Maria, Bouwstra, Joke A.
Publicado 2009

The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases

por Jacobse, Justin, ten Voorde, Wouter, Rissmann, Robert, Burggraaf, Jacobus, ten Cate, Rebecca, Schrier, Lenneke
Publicado 2018

The ultraviolet B inflammation model: Postinflammatory hyperpigmentation and validation of a reduced UVB exposure paradigm for inducing hyperalgesia in healthy subjects

por Siebenga, Pieter S., van Amerongen, Guido, Klaassen, Erica S., de Kam, Marieke L., Rissmann, Robert, Groeneveld, Geert Jan
Publicado 2019

A systematic review on disease‐drug‐drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labelling

por de Jong, Laura M., Klomp, Sylvia D., Treijtel, Nicoline, Rissmann, Robert, Swen, Jesse J., Manson, Martijn L.
Publicado 2022

Complement Activation in Inflammatory Skin Diseases

por Giang, Jenny, Seelen, Marc A. J., van Doorn, Martijn B. A., Rissmann, Robert, Prens, Errol P., Damman, Jeffrey
Publicado 2018

Integration of healthy volunteers in early phase clinical trials with immuno-oncological compounds

por Radanovic, Igor, Klarenbeek, Naomi, Rissmann, Robert, Groeneveld, Geert Jan, van Brummelen, Emilie M. J., Moerland, Matthijs, Bosch, Jacobus J.
Publicado 2022

Antimicrobial Peptide Omiganan Enhances Interferon Responses to Endosomal Toll‐Like Receptor Ligands in Human Peripheral Blood Mononuclear Cells

por Grievink, Hendrika W., Jirka, Silvana M. G., Woutman, Tess D., Schoonakker, Mascha, Rissmann, Robert, Malone, Karen E., Feiss, Gary, Moerland, Matthijs
Publicado 2020

Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models

por Nădăban, Andreea, Rousel, Jannik, El Yachioui, Dounia, Gooris, Gerrit S., Beddoes, Charlotte M., Dalgliesh, Robert M., Malfois, Marc, Rissmann, Robert, Bouwstra, Joke A.
Publicado 2023

A randomized controlled trial with a delayed‐type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man

por Saghari, Mahdi, Gal, Pim, Ziagkos, Dimitrios, Burggraaf, Jacobus, Powell, John F., Brennan, Nuala, Rissmann, Robert, van Doorn, Martijn B.A., Moerland, Matthijs
Publicado 2020

Integrin αvβ6 as a Target for Tumor-Specific Imaging of Vulvar Squamous Cell Carcinoma and Adjacent Premalignant Lesions

por Huisman, Bertine W., Cankat, Merve, Bosse, Tjalling, Vahrmeijer, Alexander L., Rissmann, Robert, Burggraaf, Jacobus, Sier, Cornelis F. M., van Poelgeest, Mariette I. E.
Publicado 2021

Comprehensive, Multimodal Characterization of an Imiquimod‐Induced Human Skin Inflammation Model for Drug Development

por van der Kolk, Tessa, Assil, Salma, Rijneveld, Rianne, Klaassen, Erica S., Feiss, Gary, Florencia, Edwin, Prens, Errol P., Burggraaf, Jacobus, Moerland, Matthijs, Rissmann, Robert, van Doorn, Martijn B.A.
Publicado 2018

The impact of CYP2C19 genotype on phenoconversion by concomitant medication

por de Jong, Laura M., Boussallami, Soukayna, Sánchez-López, Elena, Giera, Martin, Tushuizen, Maarten E., Hoekstra, Menno, Hawinkels, Lukas J. A. C., Rissmann, Robert, Swen, Jesse J., Manson, Martijn L.
Publicado 2023

The Human Vulvar Microbiome: A Systematic Review

por Pagan, Lisa, Ederveen, Roos A. M., Huisman, Bertine W., Schoones, Jan W., Zwittink, Romy D., Schuren, Frank H. J., Rissmann, Robert, Piek, Jurgen M. J., van Poelgeest, Mariëtte I. E.
Publicado 2021