Consensus Design of an Evolved High-Redox Potential Laccase

por Gomez-Fernandez, Bernardo J., Risso, Valeria A., Sanchez-Ruiz, Jose M., Alcalde, Miguel
Publicado 2020

Efficient Base-Catalyzed Kemp Elimination in an Engineered Ancestral Enzyme

por Gutierrez-Rus, Luis I., Alcalde, Miguel, Risso, Valeria A., Sanchez-Ruiz, Jose M.
Publicado 2022

Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

por Gomez-Fernandez, Bernardo J., Risso, Valeria A., Rueda, Andres, Sanchez-Ruiz, Jose M., Alcalde, Miguel
Publicado 2020

A protocol to study bacteriophage adaptation to new hosts

por Luzon-Hidalgo, Raquel, Risso, Valeria A., Delgado, Asuncion, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Publicado 2021

Evidence for a role of phenotypic mutations in virus adaptation

por Luzon-Hidalgo, Raquel, Risso, Valeria A., Delgado, Asuncion, Andrés-León, Eduardo, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Publicado 2021

Protection of Catalytic Cofactors by Polypeptides as a Driver for the Emergence of Primordial Enzymes

por Gutierrez-Rus, Luis I, Gamiz-Arco, Gloria, Gavira, J A, Gaucher, Eric A, Risso, Valeria A, Sanchez-Ruiz, Jose M
Publicado 2023

Selection for Protein Kinetic Stability Connects Denaturation Temperatures to Organismal Temperatures and Provides Clues to Archaean Life

por Romero-Romero, M. Luisa, Risso, Valeria A., Martinez-Rodriguez, Sergio, Gaucher, Eric A., Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Publicado 2016

Immunoanalytical Approach for Detecting and Identifying Ancestral Peptide Biomarkers in Early Earth Analogue Environments

por Severino, Rita, Moreno-Paz, Mercedes, Puente-Sánchez, Fernando, Sánchez-García, Laura, Risso, Valeria A., Sanchez-Ruiz, Jose M., Cabrol, Nathalie, Parro, Victor
Publicado 2023

Protein-Protein Interactions in Crystals of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512 Ectodomain

por Primo, María E., Jakoncic, Jean, Noguera, Martín E., Risso, Valeria A., Sosa, Laura, Sica, Mauricio P., Solimena, Michele, Poskus, Edgardo, Ermácora, Mario R.
Publicado 2011

Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity

por Modi, Tushar, Risso, Valeria A., Martinez-Rodriguez, Sergio, Gavira, Jose A., Mebrat, Mubark D., Van Horn, Wade D., Sanchez-Ruiz, Jose M., Banu Ozkan, S.
Publicado 2021

Enhancing a de novo enzyme activity by computationally-focused ultra-low-throughput screening

por Risso, Valeria A., Romero-Rivera, Adrian, Gutierrez-Rus, Luis I., Ortega-Muñoz, Mariano, Santoyo-Gonzalez, Francisco, Gavira, Jose A., Sanchez-Ruiz, Jose M., Kamerlin, Shina C. L.
Publicado 2020

Non-conservation of folding rates in the thioredoxin family reveals degradation of ancestral unassisted-folding

por Gamiz-Arco, Gloria, Risso, Valeria A., Candel, Adela M., Inglés-Prieto, Alvaro, Romero-Romero, Maria L., Gaucher, Eric A., Gavira, Jose A., Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Publicado 2019

Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences throughout Evolutionary History

por Risso, Valeria A., Manssour-Triedo, Fadia, Delgado-Delgado, Asunción, Arco, Rocio, Barroso-delJesus, Alicia, Ingles-Prieto, Alvaro, Godoy-Ruiz, Raquel, Gavira, Jose A., Gaucher, Eric A., Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Publicado 2015

De novo active sites for resurrected Precambrian enzymes

por Risso, Valeria A., Martinez-Rodriguez, Sergio, Candel, Adela M., Krüger, Dennis M., Pantoja-Uceda, David, Ortega-Muñoz, Mariano, Santoyo-Gonzalez, Francisco, Gaucher, Eric A., Kamerlin, Shina C. L., Bruix, Marta, Gavira, Jose A., Sanchez-Ruiz, Jose M.
Publicado 2017

Directed -in vitro- evolution of Precambrian and extant Rubiscos

por Gomez-Fernandez, Bernardo J., Garcia-Ruiz, Eva, Martin-Diaz, Javier, Gomez de Santos, Patricia, Santos-Moriano, Paloma, Plou, Francisco J., Ballesteros, Antonio, Garcia, Monica, Rodriguez, Marisa, Risso, Valeria A., Sanchez-Ruiz, Jose M., Whitney, Spencer M., Alcalde, Miguel
Publicado 2018

Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase

por Gamiz-Arco, Gloria, Gutierrez-Rus, Luis I., Risso, Valeria A., Ibarra-Molero, Beatriz, Hoshino, Yosuke, Petrović, Dušan, Justicia, Jose, Cuerva, Juan Manuel, Romero-Rivera, Adrian, Seelig, Burckhard, Gavira, Jose A., Kamerlin, Shina C. L., Gaucher, Eric A., Sanchez-Ruiz, Jose M.
Publicado 2021