A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits

por Clarke, Geraldine M., Rivas, Manuel A., Morris, Andrew P.
Publicado 2013

Mosaic mutations in blood DNA sequence are associated with solid tumor cancers

por Artomov, Mykyta, Rivas, Manuel A., Genovese, Giulio, Daly, Mark J.
Publicado 2017

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks

por Amar, David, Sinnott-Armstrong, Nasa, Ashley, Euan A., Rivas, Manuel A.
Publicado 2021

biMM: efficient estimation of genetic variances and covariances for cohorts with high-dimensional phenotype measurements

por Pirinen, Matti, Benner, Christian, Marttinen, Pekka, Järvelin, Marjo-Riitta, Rivas, Manuel A, Ripatti, Samuli
Publicado 2017

Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank

por Patel, Aniruddh P., Paranjpe, Manish D., Kathiresan, Nina P., Rivas, Manuel A., Khera, Amit V.
Publicado 2020

Time trajectories in the transcriptomic response to exercise - a meta-analysis

por Amar, David, Lindholm, Malene E., Norrbom, Jessica, Wheeler, Matthew T., Rivas, Manuel A., Ashley, Euan A.
Publicado 2021

A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

por Qian, Junyang, Tanigawa, Yosuke, Du, Wenfei, Aguirre, Matthew, Chang, Chris, Tibshirani, Robert, Rivas, Manuel A., Hastie, Trevor
Publicado 2020

Choice of transcripts and software has a large effect on variant annotation

por McCarthy, Davis J, Humburg, Peter, Kanapin, Alexander, Rivas, Manuel A, Gaulton, Kyle, Cazier, Jean-Baptiste, Donnelly, Peter
Publicado 2014

Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics

por McInnes, Gregory, Tanigawa, Yosuke, DeBoever, Chris, Lavertu, Adam, Olivieri, Julia Eve, Aguirre, Matthew, Rivas, Manuel A
Publicado 2019

Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study

por Wainberg, Michael, Mahajan, Anubha, Kundaje, Anshul, McCarthy, Mark I., Ingelsson, Erik, Sinnott-Armstrong, Nasa, Rivas, Manuel A.
Publicado 2019

Significant sparse polygenic risk scores across 813 traits in UK Biobank

por Tanigawa, Yosuke, Qian, Junyang, Venkataraman, Guhan, Justesen, Johanne Marie, Li, Ruilin, Tibshirani, Robert, Hastie, Trevor, Rivas, Manuel A.
Publicado 2022

DeepTag: inferring diagnoses from veterinary clinical notes

por Nie, Allen, Zehnder, Ashley, Page, Rodney L., Zhang, Yuhui, Pineda, Arturo Lopez, Rivas, Manuel A., Bustamante, Carlos D., Zou, James
Publicado 2018

Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

por Ruderfer, Douglas M., Walsh, Colin G., Aguirre, Matthew W., Tanigawa, Yosuke, Ribeiro, Jessica D., Franklin, Joseph C., Rivas, Manuel A.
Publicado 2019

A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population

por Tcheandjieu, Catherine, Aguirre, Matthew, Gustafsson, Stefan, Saha, Priyanka, Potiny, Praneetha, Haendel, Melissa, Ingelsson, Erik, Rivas, Manuel A., Priest, James R.
Publicado 2020

A Protein Domain and Family Based Approach to Rare Variant Association Analysis

por Richardson, Tom G., Shihab, Hashem A., Rivas, Manuel A., McCarthy, Mark I., Campbell, Colin, Timpson, Nicholas J., Gaunt, Tom R.
Publicado 2016

Assessing association between protein truncating variants and quantitative traits

por Rivas, Manuel A., Pirinen, Matti, Neville, Matthew J., Gaulton, Kyle J., Moutsianas, Loukas, Lindgren, Cecilia M., Karpe, Fredrik, McCarthy, Mark I., Donnelly, Peter
Publicado 2013

Base-specific mutational intolerance near splice sites clarifies the role of nonessential splice nucleotides

por Zhang, Sidi, Samocha, Kaitlin E., Rivas, Manuel A., Karczewski, Konrad J., Daly, Emma, Schmandt, Ben, Neale, Benjamin M., MacArthur, Daniel G., Daly, Mark J.
Publicado 2018

Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank

por Wainberg, Michael, Jones, Samuel E., Beaupre, Lindsay Melhuish, Hill, Sean L., Felsky, Daniel, Rivas, Manuel A., Lim, Andrew S. P., Ollila, Hanna M., Tripathy, Shreejoy J.
Publicado 2021

Testing for an Unusual Distribution of Rare Variants

por Neale, Benjamin M., Rivas, Manuel A., Voight, Benjamin F., Altshuler, David, Devlin, Bernie, Orho-Melander, Marju, Kathiresan, Sekar, Purcell, Shaun M., Roeder, Kathryn, Daly, Mark J.
Publicado 2011

FasTag: Automatic text classification of unstructured medical narratives

por Venkataraman, Guhan Ram, Pineda, Arturo Lopez, Bear Don’t Walk IV, Oliver J., Zehnder, Ashley M., Ayyar, Sandeep, Page, Rodney L., Bustamante, Carlos D., Rivas, Manuel A.
Publicado 2020