Metabolic fate of orally administered cGMP in rats

por Liong, Elaine, Graul, Christopher, Rivers, Samuel, Kessler, Marco, Hannig, Gerhard, Silos-Santiago, Inmaculada
Publicado 2013

Determination of cGMP levels in rodent tissues following oral dosing of a soluble guanylate cyclase stimulator

por Perez, Nisha, Graul, Christopher, Germano, Peter, Solberg, Erik, Rivers, Samuel, Solinga, Robert, Moore, Joel, Hannig, Gerhard, Silos-Santiago, Ada, Busby, Robert, Zimmer, Daniel
Publicado 2013

IWP-121: a novel sGC stimulator that reduces blood pressure and exhibits anti-fibrotic and anti-inflammatory activities in the Dahl Salt-Sensitive rat model

por Shea, Courtney, Ranganath, Sheila, Liu, Guang, Wachtel, Derek, Germano, Peter, Tobin, Jenny, Zhang, Ping, Rivers, Samuel, Im, G-Yoon Jamie, Sheppeck, James, Masferrer, Jaime
Publicado 2015

Concomitant administration of sGC stimulators with common classes of anti-hypertensive agents results in increased efficacy in spontaneously hypertensive rats

por Germano, Peter, Tobin, Jenny, Jefferson, Robert, Shea, Courtney, Smith, Adaline, Jamie Im, G-Yoon, Sheppeck, James, Wakefield, James, Sykes, Kristie, Ribadeneira, Maria, Rivers, Samuel, Masferrer, Jaime
Publicado 2015