Nonclinical and clinical pharmacological characterization of the potent and selective cathepsin K inhibitor MIV-711

por Lindström, Erik, Rizoska, Biljana, Henderson, Ian, Terelius, Ylva, Jerling, Markus, Edenius, Charlotte, Grabowska, Urszula
Publicado 2018

The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis

por Lindström, Erik, Rizoska, Biljana, Tunblad, Karin, Edenius, Charlotte, Bendele, Alison M., Maul, Don, Larson, Michael, Shah, Neha, Yoder Otto, Valerie, Jerome, Chris, Grabowska, Urszula
Publicado 2018

Analgesic effects of the cathepsin K inhibitor L-006235 in the monosodium iodoacetate model of osteoarthritis pain

por Nwosu, Lilian N., Gowler, Peter R.W., Burston, James J., Rizoska, Biljana, Tunblad, Karin, Lindström, Erik, Grabowska, Urszula, Li, Li, McWilliams, Dan F., Walsh, David A., Chapman, Victoria
Publicado 2018

The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute my...

por Yehudai, Dana, Liyanage, Sanduni U., Hurren, Rose, Rizoska, Biljana, Albertella, Mark, Gronda, Marcela, Jeyaraju, Danny V, Wang, Xiaoming, Barghout, Samir H., MacLean, Neil, Siriwardena, Thirushi P., Jitkova, Yulia, Targett-Adams, Paul, Schimmer, Aaron D.
Publicado 2019

Novel L-nucleoside analog, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia

por Bankar, Aniket, Siriwardena, Thirushi Piyumika, Rizoska, Biljana, Rydergård, Christina, Kylefjord, Helen, Rraklli, Vilma, Eneroth, Anders, Pinho, Pedro, Norin, Stefan, Bylund, Johan, Moses, Sara, Bethell, Richard, Kavanagh, Simon, Maclean, Neil, Gronda, Marcela, Wang, Xiaoming, Hurren, Rose, Minden, Mark D., Targett-Adams, Paul, Schimmer, Aaron D., Albertella, Mark
Publicado 2019