Nanomedicines Meet Disordered Proteins: A Shift from Traditional Materials and Concepts to Innovative Polymers

por Rizzuti, Bruno
Publicado 2022

Deciphering the Binding of the Nuclear Localization Sequence of Myc Protein to the Nuclear Carrier Importin α3

por Rizzuti, Bruno, Iovanna, Juan L., Neira, José L.
Publicado 2022

Conformational Stability of the N-Terminal Region of MDM2

por Rizzuti, Bruno, Abian, Olga, Velazquez-Campoy, Adrián, Neira, José L.
Publicado 2023

The C Terminus of the Ribosomal-Associated Protein LrtA Is an Intrinsically Disordered Oligomer

por Neira, José L., Giudici, A. Marcela, Hornos, Felipe, Arbe, Arantxa, Rizzuti, Bruno
Publicado 2018

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer

por Kampa, Marilena, Lappano, Rosamaria, Grande, Fedora, Rizzuti, Bruno, Maggiolini, Marcello, Castanas, Elias, Jacquot, Yves
Publicado 2023

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

por Neira, José L., Rizzuti, Bruno, Jiménez-Alesanco, Ana, Abián, Olga, Velázquez-Campoy, Adrián, Iovanna, Juan L.
Publicado 2020

Polyphenols from Citrus Tacle(®) Extract Endowed with HMGCR Inhibitory Activity: An Antihypercholesterolemia Natural Remedy

por Grande, Fedora, Occhiuzzi, Maria Antonietta, Perri, Maria Rosaria, Ioele, Giuseppina, Rizzuti, Bruno, Statti, Giancarlo, Garofalo, Antonio
Publicado 2021

Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners

por Neira, José L., Ortega-Alarcón, David, Rizzuti, Bruno, Palomino-Schätzlein, Martina, Velázquez-Campoy, Adrián, Falcó, Alberto
Publicado 2021

Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation

por De Luca, Michele, Occhiuzzi, Maria Antonietta, Rizzuti, Bruno, Ioele, Giuseppina, Ragno, Gaetano, Garofalo, Antonio, Grande, Fedora
Publicado 2022

Human Enzyme PADI4 Binds to the Nuclear Carrier Importin α3

por Neira, José L., Rizzuti, Bruno, Abián, Olga, Araujo-Abad, Salomé, Velázquez-Campoy, Adrián, de Juan Romero, Camino
Publicado 2022

The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect

por Hornos, Felipe, Feng, Han-Zhong, Rizzuti, Bruno, Palomino-Schätzlein, Martina, Wieczorek, David, Neira, José L., Jin, J.-P.
Publicado 2021

Identification by Molecular Docking of Homoisoflavones from Leopoldia comosa as Ligands of Estrogen Receptors

por Grande, Fedora, Rizzuti, Bruno, Occhiuzzi, Maria A., Ioele, Giuseppina, Casacchia, Teresa, Gelmini, Fabrizio, Guzzi, Rita, Garofalo, Antonio, Statti, Giancarlo
Publicado 2018

Targeting intrinsically disordered proteins involved in cancer

por Santofimia-Castaño, Patricia, Rizzuti, Bruno, Xia, Yi, Abian, Olga, Peng, Ling, Velázquez-Campoy, Adrián, Neira, José L., Iovanna, Juan
Publicado 2019

Computational Approaches for the Discovery of GPER Targeting Compounds

por Grande, Fedora, Occhiuzzi, Maria A., Lappano, Rosamaria, Cirillo, Francesca, Guzzi, Rita, Garofalo, Antonio, Jacquot, Yves, Maggiolini, Marcello, Rizzuti, Bruno
Publicado 2020

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

por Neira, José L., Rizzuti, Bruno, Jiménez-Alesanco, Ana, Palomino-Schätzlein, Martina, Abián, Olga, Velázquez-Campoy, Adrián, Iovanna, Juan L.
Publicado 2020

CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

por Grande, Fedora, Occhiuzzi, Maria Antonietta, Rizzuti, Bruno, Ioele, Giuseppina, De Luca, Michele, Tucci, Paola, Svicher, Valentina, Aquaro, Stefano, Garofalo, Antonio
Publicado 2019

Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening

por Abian, Olga, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Reyburn, Hugh T., Rizzuti, Bruno, Velazquez-Campoy, Adrian
Publicado 2020

Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1

por Bonucci, Alessio, Palomino-Schätzlein, Martina, Malo de Molina, Paula, Arbe, Arantxa, Pierattelli, Roberta, Rizzuti, Bruno, Iovanna, Juan L., Neira, José L.
Publicado 2021

Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds

por Rizzuti, Bruno, Ceballos-Laita, Laura, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Vega, Sonia, Grande, Fedora, Conforti, Filomena, Abian, Olga, Velazquez-Campoy, Adrian
Publicado 2021

Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

por Neira, José L., Bintz, Jennifer, Arruebo, María, Rizzuti, Bruno, Bonacci, Thomas, Vega, Sonia, Lanas, Angel, Velázquez-Campoy, Adrián, Iovanna, Juan L., Abián, Olga
Publicado 2017