Cwp84, a Clostridium difficile cysteine protease, exhibits conformational flexibility in the absence of its propeptide

por Bradshaw, William J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2015

Structure and function of a Clostridium difficile sortase enzyme

por Chambers, Christopher J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2015

The structure of the S-layer of Clostridium difficile

por Bradshaw, William J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2017

Expression, purification, crystallization and preliminary crystallographic analysis of a putative Clostridium difficile surface protein Cwp19

por Kirby, Jonathan M., Thiyagarajan, Nethaji, Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2011

Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro

por Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2017

The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile

por Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2017

Functional significance of active site residues in the enzymatic component of the Clostridium difficile binary toxin

por Davies, Abigail H., McGlashan, Joanna, Posner, Mareike G., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2016

The structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein from Clostridium difficile

por Bradshaw, William J., Kirby, Jonathan M., Thiyagarajan, Nethaji, Chambers, Christopher J., Davies, Abigail H., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado 2014

A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Clostridioides difficile Infection in Pre-clinical Models

por Roberts, April K., Harris, Hannah C., Smith, Michael, Giles, Joanna, Polak, Oktawia, Buckley, Anthony M., Clark, Emma, Ewin, Duncan, Moura, Ines B., Spitall, William, Shone, Clifford C., Wilcox, Mark, Chilton, Caroline, Donev, Rossen
Publicado 2020