Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

por Velkov, Tony, Roberts, Kade D., Nation, Roger L., Wang, Jiping, Thompson, Philip E., Li, Jian
Publicado 2014

Design and Evaluation of Novel Polymyxin Fluorescent Probes

por Yun, Bo, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Publicado 2017

Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells

por Li, Mengyao, Azad, Mohammad A. K., Thompson, Philip E., Roberts, Kade D., Velkov, Tony, Zhu, Yan, Li, Jian
Publicado 2023

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

por Deris, Zakuan Z., Akter, Jesmin, Sivanesan, Sivashangarie, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Li, Jian, Velkov, Tony
Publicado 2013

Transcriptomic Analysis of the Activity of a Novel Polymyxin against Staphylococcus aureus

por Zhao, Jinxin, Cheah, Soon-Ee, Roberts, Kade D., Nation, Roger L., Thompson, Philip E., Velkov, Tony, Du, Zongjun, Johnson, Matthew D., Li, Jian
Publicado 2016

Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules

por Schneider-Futschik, Elena K., Paulin, Olivia K. A., Hoyer, Daniel, Roberts, Kade D., Ziogas, James, Baker, Mark A., Karas, John, Li, Jian, Velkov, Tony
Publicado 2018

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria

por Deris, Zakuan Z., Swarbrick, James D., Roberts, Kade D., Azad, Mohammad A. K., Akter, Jesmin, Horne, Andrew. S., Nation, Roger L., Rogers, Kelly L., Thompson, Phillip E., Velkov, Tony, Li, Jian
Publicado 2014

An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates

por Patil, Nitin A., Thombare, Varsha J., Li, Rong, He, Xiaoji, Lu, Jing, Yu, Heidi H., Wickremasinghe, Hasini, Pamulapati, Kavya, Azad, Mohammad A. K., Velkov, Tony, Roberts, Kade D., Li, Jian
Publicado 2022

Significant Accumulation of Polymyxin in Single Renal Tubular Cells: A Medicinal Chemistry and Triple Correlative Microscopy Approach

por Azad, Mohammad A. K., Roberts, Kade D., Yu, Heidi H., Liu, Boyin, Schofield, Alice V., James, Simon A., Howard, Daryl L., Nation, Roger L., Rogers, Kelly, de Jonge, Martin D., Thompson, Philip E., Fu, Jing, Velkov, Tony, Li, Jian
Publicado 2015

A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii

por Jiang, Xukai, Patil, Nitin A., Azad, Mohammad A. K., Wickremasinghe, Hasini, Yu, Heidi, Zhao, Jinxin, Zhang, Xinru, Li, Mengyao, Gong, Bin, Wan, Lin, Ma, Wendong, Thompson, Philip E., Yang, Kai, Yuan, Bing, Schreiber, Falk, Wang, Lushan, Velkov, Tony, Roberts, Kade D., Li, Jian
Publicado 2021

A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

por Roberts, Kade D., Zhu, Yan, Azad, Mohammad A. K., Han, Mei-Ling, Wang, Jiping, Wang, Lynn, Yu, Heidi H., Horne, Andrew S., Pinson, Jo-Anne, Rudd, David, Voelcker, Nicolas H., Patil, Nitin A., Zhao, Jinxin, Jiang, Xukai, Lu, Jing, Chen, Ke, Lomovskaya, Olga, Hecker, Scott J., Thompson, Philip E., Nation, Roger L., Dudley, Michael N., Griffith, David C., Velkov, Tony, Li, Jian
Publicado 2022