Osteosarcoma Multi-Omics Landscape and Subtypes

por Tang, Shan, Roberts, Ryan D., Cheng, Lijun, Li, Lang
Publicado 2023

Osteosarcoma: Accelerating Progress Makes for a Hopeful Future

por Saraf, Amanda J., Fenger, Joelle M., Roberts, Ryan D.
Publicado 2018

Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression

por Fan, Timothy M., Roberts, Ryan D., Lizardo, Michael M.
Publicado 2020

Characterizing the metabolic role of STAT3 in canine osteosarcoma

por Gardner, Heather L., Fenger, Joelle M., Roberts, Ryan D., London, Cheryl A.
Publicado 2022

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

por Charan, Manish, Dravid, Piyush, Cam, Maren, Setty, Bhuvana, Roberts, Ryan D., Houghton, Peter J., Cam, Hakan
Publicado 2020

Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time

por Rajan, Sanjana, Zaccaria, Simone, Cannon, Matthew V., Cam, Maren, Gross, Amy C., Raphael, Benjamin J., Roberts, Ryan D.
Publicado 2023

M-CSF Signals through the MAPK/ERK Pathway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo

por Curry, Jennifer M., Eubank, Tim D., Roberts, Ryan D., Wang, Yijie, Pore, Nabendu, Maity, Amit, Marsh, Clay B.
Publicado 2008

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

por Cam, Maren, Gardner, Heather L., Roberts, Ryan D., Fenger, Joelle M., Guttridge, Denis C., London, Cheryl A., Cam, Hakan
Publicado 2016

Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy

por Haworth, Kellie B., Arnold, Michael A., Pierson, Christopher R., Choi, Kwangmin, Yeager, Nicholas D., Ratner, Nancy, Roberts, Ryan D., Finlay, Jonathan L., Cripe, Timothy P.
Publicado 2017

Immunotherapeutic Challenges for Pediatric Cancers

por Hutzen, Brian, Ghonime, Mohammed, Lee, Joel, Mardis, Elaine R., Wang, Ruoning, Lee, Dean A., Cairo, Mitchell S., Roberts, Ryan D., Cripe, Timothy P., Cassady, Kevin A.
Publicado 2019

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines

por Fenger, Joelle M., Roberts, Ryan D., Iwenofu, O. Hans, Bear, Misty D., Zhang, Xiaoli, Couto, Jason I., Modiano, Jaime F., Kisseberth, William C., London, Cheryl A.
Publicado 2016

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

por Rajan, Sanjana, Franz, Emily M., McAloney, Camille A., Vetter, Tatyana A., Cam, Maren, Gross, Amy C., Taslim, Cenny, Wang, Meng, Cannon, Matthew V., Oles, Alexander, Roberts, Ryan D.
Publicado 2023

An evolutionary framework for treating pediatric sarcomas

por Reed, Damon R., Metts, Jonathan, Pressley, Mariyah, Fridley, Brooke L., Hayashi, Masanori, Isakoff, Michael S., Loeb, David M., Makanji, Rikesh, Roberts, Ryan D., Trucco, Matteo, Wagner, Lars M., Alexandrow, Mark G., Gatenby, Robert A., Brown, Joel S.
Publicado 2020

Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma

por Wedekind, Mary Frances, Miller, Katherine E., Chen, Chun-Yu, Wang, Pin-Yi, Hutzen, Brian J., Currier, Mark A., Nartker, Brooke, Roberts, Ryan D., Boon, Louis, Conner, Joe, LaHaye, Stephanie, Kelly, Benjamin J., Gordon, David, White, Peter, Mardis, Elaine R., Cripe, Timothy P.
Publicado 2021

Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution

por Hedberg, Jack, Studebaker, Adam, Smith, Luke, Chen, Chun-Yu, Westfall, Jesse J., Cam, Maren, Gross, Amy, Hernandez-Aguirre, Ilse, Martin, Alexia, Kim, Doyeon, Dhital, Ravi, Kim, Yeaseul, Roberts, Ryan D., Cripe, Timothy P., Mardis, Elaine R., Cassady, Kevin A., Leonard, Jeffrey, Miller, Katherine E.
Publicado 2023

An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma

por Shulman, David S., Whittle, Sarah B., Surdez, Didier, Bailey, Kelly M., de Álava, Enrique, Yustein, Jason T., Shlien, Adam, Hayashi, Masanori, Bishop, Alexander J. R., Crompton, Brian D., DuBois, Steven G., Shukla, Neerav, Leavey, Patrick J., Lessnick, Stephen L., Kovar, Heinrich, Delattre, Olivier, Grünewald, Thomas G. P., Antonescu, Cristina R., Roberts, Ryan D., Toretsky, Jeffrey A., Tirode, Franck, Gorlick, Richard, Janeway, Katherine A., Reed, Damon, Lawlor, Elizabeth R., Grohar, Patrick J.
Publicado 2022