Clonality in haematopoietic stem cell ageing

por Terradas-Terradas, Maria, Robertson, Neil A., Chandra, Tamir, Kirschner, Kristina
Publicado 2020

Purifying stem cell‐derived red blood cells: a high‐throughput label‐free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration...

por Guzniczak, Ewa, Otto, Oliver, Whyte, Graeme, Chandra, Tamir, Robertson, Neil A., Willoughby, Nik, Jimenez, Melanie, Bridle, Helen
Publicado 2020

Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts

por Cole, John J., Faydaci, Bekir A., McGuinness, David, Shaw, Robin, Maciewicz, Rose A., Robertson, Neil A., Goodyear, Carl S.
Publicado 2021

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

por Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Publicado 2018

Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

por Wang, Tina, Tsui, Brian, Kreisberg, Jason F., Robertson, Neil A., Gross, Andrew M., Yu, Michael Ku, Carter, Hannah, Brown-Borg, Holly M., Adams, Peter D., Ideker, Trey
Publicado 2017

DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation

por MacKenzie, Douglas J., Robertson, Neil A., Rather, Iqbal, Reid, Claire, Sendzikaite, Gintare, Cruickshanks, Hazel, McBryan, Tony, Hodges, Andrew, Pritchard, Catrin, Blyth, Karen, Adams, Peter D.
Publicado 2020

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

por Cole, John J., Robertson, Neil A., Rather, Mohammed Iqbal, Thomson, John P., McBryan, Tony, Sproul, Duncan, Wang, Tina, Brock, Claire, Clark, William, Ideker, Trey, Meehan, Richard R., Miller, Richard A., Brown-Borg, Holly M., Adams, Peter D.
Publicado 2017

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

por Vizioli, Maria Grazia, Liu, Tianhui, Miller, Karl N., Robertson, Neil A., Gilroy, Kathryn, Lagnado, Anthony B., Perez-Garcia, Arantxa, Kiourtis, Christos, Dasgupta, Nirmalya, Lei, Xue, Kruger, Patrick J., Nixon, Colin, Clark, William, Jurk, Diana, Bird, Thomas G., Passos, João F., Berger, Shelley L., Dou, Zhixun, Adams, Peter D.
Publicado 2020

Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

por Robertson, Neil A., Latorre-Crespo, Eric, Terradas-Terradas, Maria, Lemos-Portela, Jorge, Purcell, Alison C., Livesey, Benjamin J., Hillary, Robert F., Murphy, Lee, Fawkes, Angie, MacGillivray, Louise, Copland, Mhairi, Marioni, Riccardo E., Marsh, Joseph A., Harris, Sarah E., Cox, Simon R., Deary, Ian J., Schumacher, Linus J., Kirschner, Kristina, Chandra, Tamir
Publicado 2022

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigen...

por Nelson, David M., Jaber-Hijazi, Farah, Cole, John J., Robertson, Neil A., Pawlikowski, Jeffrey S., Norris, Kevin T., Criscione, Steven W., Pchelintsev, Nikolay A., Piscitello, Desiree, Stong, Nicholas, Rai, Taranjit Singh, McBryan, Tony, Otte, Gabriel L., Nixon, Colin, Clark, William, Riethman, Harold, Wu, Hong, Schotta, Gunnar, Garcia, Benjamin A., Neretti, Nicola, Baird, Duncan M., Berger, Shelley L., Adams, Peter D.
Publicado 2016

BRD4-mediated repression of p53 is a target for combination therapy in AML

por Latif, Anne-Louise, Newcombe, Ashley, Li, Sha, Gilroy, Kathryn, Robertson, Neil A., Lei, Xue, Stewart, Helen J. S., Cole, John, Terradas, Maria Terradas, Rishi, Loveena, McGarry, Lynn, McKeeve, Claire, Reid, Claire, Clark, William, Campos, Joana, Kirschner, Kristina, Davis, Andrew, Lopez, Jonathan, Sakamaki, Jun-ichi, Morton, Jennifer P., Ryan, Kevin M., Tait, Stephen W. G., Abraham, Sheela A., Holyoake, Tessa, Higgins, Brian, Huang, Xu, Blyth, Karen, Copland, Mhairi, Chevassut, Timothy J. T., Keeshan, Karen, Adams, Peter D.
Publicado 2021

Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

por Gadd, Danni A., Hillary, Robert F., McCartney, Daniel L., Shi, Liu, Stolicyn, Aleks, Robertson, Neil A., Walker, Rosie M., McGeachan, Robert I., Campbell, Archie, Xueyi, Shen, Barbu, Miruna C., Green, Claire, Morris, Stewart W., Harris, Mathew A., Backhouse, Ellen V., Wardlaw, Joanna M., Steele, J. Douglas, Oyarzún, Diego A., Muniz-Terrera, Graciela, Ritchie, Craig, Nevado-Holgado, Alejo, Chandra, Tamir, Hayward, Caroline, Evans, Kathryn L., Porteous, David J., Cox, Simon R., Whalley, Heather C., McIntosh, Andrew M., Marioni, Riccardo E.
Publicado 2022