BIOL-01. THE RELATIONSHIP OF BRAIN ENDOTHELIAL WNT SIGNAL INHIBITION ON BLOOD-TUMOR BARRIER INTEGRITY

por Jackson, Sadhana, Vezina, Amelie, Kundu, Nabanita, Robey, Robert
Publicado 2021

New mechanisms of multidrug resistance: an introduction to the Cancer Drug Resistance special collection

por Gottesman, Michael M., Robey, Robert W., Ambudkar, Suresh V.
Publicado 2023

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

por Lusvarghi, Sabrina, Robey, Robert W., Gottesman, Michael M., Ambudkar, Suresh V.
Publicado 2020

TRLS-03. IBRUTINIB DISRUPTS BLOOD-TUMOR BARRIER INTEGRITY TO ENHANCE CNS DRUG DELIVERY AND RODENT GLIOMA MODEL SURVIVAL

por Lim, Sanghee, Kwak, Minhye, Tang, Kayen, Cesaire, Melissa, Robey, Robert, Gottesman, Michael, Jackson, Sadhana
Publicado 2023

ATP-binding cassette transporters at the zebrafish blood-brain barrier and the potential utility of the zebrafish as an in vivo model

por Hotz, Jordan M., Thomas, Joanna R., Katz, Emily N., Robey, Robert W., Horibata, Sachi, Gottesman, Michael M.
Publicado 2021

Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer

por Lipsey, Crystal C., Harbuzariu, Adriana, Robey, Robert W., Huff, Lyn M., Gottesman, Michael M., Gonzalez-Perez, Ruben R.
Publicado 2020

Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms

por Patel, Ruchi P., Kuhn, Skyler, Yin, Da, Hotz, Jordan, Maher, Frances A., Robey, Robert W., Gottesman, Michael M., Horibata, Sachi
Publicado 2020

Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and their Zebrafish Homologs at the Blood-Brain Barrier

por Inglut, Collin T., Quinlan, John A., Robey, Robert W., Thomas, Joanna R., Walker, Joel R., Zhou, Wenhui, Huang, Huang-Chiao, Gottesman, Michael M.
Publicado 2023

A Histone Deacetylase Inhibitor Induces Acetyl-CoA Depletion Leading to Lethal Metabolic Stress in RAS-Pathway Activated Cells

por Basseville, Agnes, Violet, Pierre-Christian, Safari, Maryam, Sourbier, Carole, Linehan, W. Marston, Robey, Robert W., Levine, Mark, Sackett, Dan L., Bates, Susan E.
Publicado 2022

Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms

por Safari, Maryam, Scotto, Luigi, Litman, Thomas, Petrukhin, Lubov A., Zhu, Hu, Shen, Min, Robey, Robert W., Hall, Matthew D., Fojo, Tito, Bates, Susan E.
Publicado 2023

Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma

por Patel, Ruchi P., Thomas, Joanna R., Curt, Katherine M., Fitzsimmons, Christina M., Batista, Pedro J., Bates, Susan E., Gottesman, Michael M., Robey, Robert W.
Publicado 2021

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

por Thomas, Joanna R., Frye, William J. E., Robey, Robert W., Warner, Andrew C., Butcher, Donna, Matta, Jennifer L., Morgan, Tamara C., Edmondson, Elijah F., Gottesman, Michael M.
Publicado 2023

Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras

por Bahr, Julian C., Robey, Robert W., Luchenko, Victoria, Basseville, Agnes, Chakraborty, Arup R., Kozlowski, Hanna, Pauly, Gary T., Patel, Paresma, Schneider, Joel P., Gottesman, Michael M., Bates, Susan E.
Publicado 2016

Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis

por Amawi, Haneen, Hussein, Noor A., Ashby, Charles R., Alnafisah, Rawan, Sanglard, Leticia M., Manivannan, Elangovan, Karthikeyan, Chandrabose, Trivedi, Piyush, Eisenmann, Kathryn M., Robey, Robert W., Tiwari, Amit K.
Publicado 2018

The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers

por Frye, William J. E., Huff, Lyn M., González Dalmasy, José M., Salazar, Paula, Carter, Rachel M., Gensler, Ryan T., Esposito, Dominic, Robey, Robert W., Ambudkar, Suresh V., Gottesman, Michael M.
Publicado 2023

R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin

por Safari, Maryam, Litman, Thomas, Robey, Robert W., Aguilera, Andrés, Chakraborty, Arup R., Reinhold, William C., Basseville, Agnes, Petrukhin, Lubov, Scotto, Luigi, O'Connor, Owen A., Pommier, Yves, Fojo, Antonio T., Bates, Susan E.
Publicado 2021

Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2

por Wang, De-Shen, Patel, Atish, Shukla, Suneet, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J., Robey, Robert W., Zhang, Li, Yang, Dong-Hua, Talele, Tanaji T., Bates, Susan E., Ambudkar, Suresh V., Xu, Rui-Hua, Chen, Zhe-Sheng
Publicado 2014

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

por Robey, Robert W., Robinson, Andrea N., Ali-Rahmani, Fatima, Huff, Lyn M., Lusvarghi, Sabrina, Vahedi, Shahrooz, Hotz, Jordan M., Warner, Andrew C., Butcher, Donna, Matta, Jennifer, Edmondson, Elijah F., Lee, Tobie D., Roth, Jacob S., Lee, Olivia W., Shen, Min, Tanner, Kandice, Hall, Matthew D., Ambudkar, Suresh V., Gottesman, Michael M.
Publicado 2021

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

por Giddings, Emily L., Champagne, Devin P., Wu, Meng-Han, Laffin, Joshua M., Thornton, Tina M., Valenca-Pereira, Felipe, Culp-Hill, Rachel, Fortner, Karen A., Romero, Natalia, East, James, Cao, Phoebe, Arias-Pulido, Hugo, Sidhu, Karatatiwant S., Silverstrim, Brian, Kam, Yoonseok, Kelley, Shana, Pereira, Mark, Bates, Susan E., Bunn, Janice Y., Fiering, Steven N., Matthews, Dwight E., Robey, Robert W., Stich, Domink, D’Alessandro, Angelo, Rincon, Mercedes
Publicado 2021