Development of Molecularly Targeted Therapies to Treat Pediatric Malignancies

por Stewart, Clinton F., Robinson, Giles W.
Publicado 2017

Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy

por Robinson, Giles W, Orr, Brent A, Gajjar, Amar
Publicado 2014

Rare cases of medulloblastoma with hypermutation

por Bagchi, Aditi, Beddows, Ian, Cornelius, Albert, Robinson, Giles W., Jewell, Scott D.
Publicado 2021

Low-coverage whole-genome sequencing of cerebrospinal-fluid-derived cell-free DNA in brain tumor patients

por Liu, Anthony P.Y., Smith, Kyle S., Kumar, Rahul, Robinson, Giles W., Northcott, Paul A.
Publicado 2022

PATH-09. SJMB12 CLINICAL TRIAL: DISCREPANCY BETWEEN LOCAL AND CENTRAL PATHOLOGY IN ASSESSING ANAPLASTIC MEDULLOBLASTOMA – REPORT FROM A SINGLE SITE EXPERIENCE

por Khuong-Quang, Dong-Anh, Williamson, Karli, MacGregor, Duncan, Orr, Brent A, Gajjar, Amar, Robinson, Giles W, Sullivan, Michael J, Hansford, Jordan R
Publicado 2020

INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors.

por Jonchere, Barbara, Pribnow, Allison, Morfouace, Marie, Shelat, Anang, Yu, Jiyang, Rankovic, Zoran, Gajjar, Amar, Northcott, Paul A, Robinson, Giles W, Roussel, Martine F
Publicado 2022

DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts

por Tran, Quynh T., Upadhyaya, Santhosh A., Billups, Catherine A., Onar-Thomas, Arzu, Alom, Md. Zahangir, Carey, Steven S., Robinson, Giles W., Ellison, David W., Gajjar, Amar, Orr, Brent A.
Publicado 2023

Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors

por Morfouace, Marie, Nimmervoll, Birgit, Boulos, Nidal, Patel, Yogesh T., Shelat, Anang, Freeman, Burgess B., Robinson, Giles W., Wright, Karen, Gajjar, Amar, Stewart, Clinton F., Gilbertson, Richard J., Roussel, Martine F.
Publicado 2015

MBRS-24. FUNCTIONAL CHARACTERIZATION OF IKBKAP/ELP1 AS A NOVEL SHH MEDULLOBLASTOMA PREDISPOSITION GENE

por Lopez, Jesus Garcia, Kutscher, Lena, Kojic, Marija, Gudenas, Brian, Smith, Kyle, Hadley, Jennifer, Gajjar, Amar, Robinson, Giles W, Pfister, Stefan M, Wainwright, Brandon J, Kawauchi, Daisuke, Northcott, Paul A
Publicado 2020

Primary cilia control translation and the cell cycle in medulloblastoma

por Youn, Yong Ha, Hou, Shirui, Wu, Chang-Chih, Kawauchi, Daisuke, Orr, Brent A., Robinson, Giles W., Finkelstein, David, Taketo, Makoto M., Gilbertson, Richard J., Roussel, Martine F., Han, Young-Goo
Publicado 2022

(11)C-Methionine PET for Identification of Pediatric High-Grade Glioma Recurrence

por Bag, Asim K., Wing, Melissa N., Sabin, Noah D., Hwang, Scott N., Armstrong, Gregory T., Han, Yuanyuan, Li, Yimei, Snyder, Scott E., Robinson, Giles W., Qaddoumi, Ibrahim, Broniscer, Alberto, Lucas, John T., Shulkin, Barry L.
Publicado 2022

Reducing Wait Time in a High-volume Pediatric Neuro-oncology Clinic by Optimizing Process Flow: A Quality Improvement Project

por Vinitsky, Anna, David, Barbara, Michalik, Layna, Ramirez, Nicole, Risinger, Adam, Burlison, Jonathan D., Zanders, Jacky, Mans, Bridget, Heady, Katie, Holdiness, Joni, Qaddoumi, Ibrahim, Robinson, Giles W., Moreira, Daniel, Upadhyaya, Santhosh A., Gajjar, Amar
Publicado 2022

MEDB-69. Clinical and molecular meta-analysis of three major medulloblastoma clinical trials (ACNS0331, SJMB03, ACNS0332) uncovers novel strategies to improve risk-stratified thera...

por Smith, Kyle S, Billups, Catherine A, Dhanda, Sandeep K, Bihannic, Laure, Vasilyeva, Aksana, Li, Yimei, Michalski, Jeff M, Olsen, James M, Leary, Sarah, Fouladi, Maryam, Gajjar, Amar, Onar, Arzu, Northcott, Paul A, Robinson, Giles W
Publicado 2022

Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma

por Pribnow, Allison, Jonchere, Barbara, Liu, Jingjing, Smith, Kyle S., Campagne, Olivia, Xu, Ke, Robinson, Sarah, Patel, Yogesh, Onar-Thomas, Arzu, Wu, Gang, Stewart, Clinton F., Northcott, Paul A., Yu, Jiyang, Robinson, Giles W., Roussel, Martine F.
Publicado 2022

A sellar presentation of a WNT-activated embryonal tumor: further evidence of an ectopic medulloblastoma

por Tauziède-Espariat, Arnault, Simbozel, Marie, Liu, Anthony P. Y., Robinson, Giles W., Masliah-Planchon, Julien, Sievers, Philipp, Vasiljevic, Alexandre, Duchesne, Mathilde, Puget, Stéphanie, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Métais, Alice, Hasty, Lauren, Dufour, Christelle, Varlet, Pascale
Publicado 2023

Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

por Robinson, Giles W., Kaste, Sue C., Chemaitilly, Wassim, Bowers, Daniel C., Laughton, Stephen, Smith, Amy, Gottardo, Nicholas G., Partap, Sonia, Bendel, Anne, Wright, Karen D., Orr, Brent A., Warner, William C., Onar-Thomas, Arzu, Gajjar, Amar
Publicado 2017

ATRT-22. Outcomes for children with recurrent atypical teratoid rhabdoid tumor: A single institution study with updated molecular and germline analysis

por Carey, Steven S, Huang, Jie, Myers, Jason R, Mostafavi, Roya, Orr, Brent, Michalik, Layna H, Klimo, Paul, Boop, Frederick, Nichols, Kim E, Merchant, Thomas, Ellison, David W, Robinson, Giles W, Onar-Thomas, Arzu, Gajjar, Amar, Upadhyaya, Santhosh
Publicado 2022

MBRS-20. CSF-DERIVED CIRCULATING TUMOR DNA AS A BIOMARKER FOR DISEASE PROGRESSION AND TUMOR EVOLUTION IN MEDULLOBLASTOMA

por Liu, Anthony Pak-Yin, Kumar, Rahul, Kyle, Smith, Paul, Leena, Chintagumpala, Murali, Bouffet, Eric, Fisher, Michael J, Hassall, Tim, Gururangan, Sri, Hansford, Jordan, Cohn, Richard, Ellison, David W, Gilbertson, Richard J, Gajjar, Amar, Robinson, Giles W, Northcott, Paul A
Publicado 2020

Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource

por Smith, Kyle S., Xu, Ke, Mercer, Kimberly S., Boop, Frederick, Klimo, Paul, DeCupyere, Michael, Grenet, Jose, Robinson, Sarah, Dunphy, Paige, Baker, Suzanne J., Ellison, David W., Merchant, Thomas E., Upadayaya, Santhosh A., Gajjar, Amar, Wu, Gang, Orr, Brent A., Robinson, Giles W., Northcott, Paul A., Roussel, Martine F.
Publicado 2020

LGG-22. SJ901: Phase I/II evaluation of single agent mirdametinib (PD-0325901), a brain-penetrant MEK1/2 inhibitor, for the treatment of children, adolescents, and young adults wit...

por Vinitsky, Anna, Chiang, Jason, Bag, Asim K, Campagne, Olivia, Stewart, Clinton F, Dunphy, Paige, Shulkin, Barry, Li, Qian, Lin, Tong, Hoehn, Mary Ellen, Johnson, Jason N, Towbin, Jeffrey A, Khan, Raja, Tatevossian, Ruth G, Armstrong, Gregory T, Potter, Brian, Conklin, Heather, Shearer, Todd, Scott, Susan, Robinson, Giles W
Publicado 2022