COMBINING SCLEROSTIN AND DKK1 INHIBITORS TO IMPROVE BONE PROPERTIES IN THE AGED SKELETON

por Choi, Roy, Robling, Alexander
Publicado 2022

New Insights into Wnt–Lrp5/6–β-Catenin Signaling in Mechanotransduction

por Kang, Kyung Shin, Robling, Alexander G.
Publicado 2015

Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia

por Niziolek, Paul J., Bullock, Whitney, Warman, Matthew L., Robling, Alexander G.
Publicado 2015

L‐BAIBA Synergizes with Sub‐Optimal Mechanical Loading to Promote New Bone Formation

por Prideaux, Matt, Smargiassi, Alberto, Peng, Gang, Brotto, Marco, Robling, Alexander G, Bonewald, Lynda F
Publicado 2023

SAT-337 Disruption Of The Circadian Melatonin Signal By Dim Light At Night Promotes Bone-lytic Breast Cancer Metastases

por Anbalagan, Muralidharan, Dauchy, Robert, Xiang, Shulin, Robling, Alexander, Blask, David, Rowan, Brian, Hill, Steven
Publicado 2019

Quick and inexpensive paraffin-embedding method for dynamic bone formation analyses

por Porter, Amy, Irwin, Regina, Miller, Josselyn, Horan, Daniel J., Robling, Alexander G., McCabe, Laura R.
Publicado 2017

Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms

por Feng, Yan, Liu, Shengzhi, Zha, Rongrong, Sun, Xun, Li, Kexin, Robling, Alexander, Li, Baiyan, Yokota, Hiroki
Publicado 2021

Effects of PTH glandular and external dosing patterns on bone cell activity using a two-state receptor model—Implications for bone disease progression and treatment

por Martonová, Denisa, Lavaill, Maxence, Forwood, Mark R., Robling, Alexander, Cooper, David M. L., Leyendecker, Sigrid, Pivonka, Peter
Publicado 2023

Suppression of Sost/Sclerostin and Dickkopf‐1 Augment Intervertebral Disc Structure in Mice

por Kroon, Tori, Bhadouria, Neharika, Niziolek, Paul, Edwards, Daniel, Choi, Roy, Clinkenbeard, Erica L, Robling, Alexander, Holguin, Nilsson
Publicado 2022

Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth

por Mathis, Noah J., Adaniya, Emily N., Smith, Lauren M., Robling, Alexander G., Jepsen, Karl J., Schlecht, Stephen H.
Publicado 2019

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

por Choi, Roy B, Bullock, Whitney A, Hoggatt, April M, Loots, Gabriela G, Genetos, Damian C, Robling, Alexander G
Publicado 2021

Targeting Sclerostin and Dkk1 at Optimized Proportions of Low-Dose Antibody Achieves Similar Skeletal Benefits to Higher-Dose Sclerostin Targeting in the Mature Adult and Aged Skel...

por Choi, Roy B., Hoggatt, April M., Horan, Daniel J., Rogers, Emily Z., Hong, Jung Min, Robling, Alexander G.
Publicado 2022

Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization

por Lewis, Karl J., Choi, Roy B-J, Pemberton, Emily Z., Bullock, Whitney A., Firulli, Anthony B., Robling, Alexander G.
Publicado 2019

The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells

por Lewis, Karl J, Yi, Xin, Wright, Christian S, Pemberton, Emily Z, Bullock, Whitney A, Thompson, William R, Robling, Alexander G
Publicado 2020

The role of Meteorin‐like in skeletal development and bone fracture healing

por Huang, Rong, Balu, Abhinav R., Molitoris, Kristin H., White, James P., Robling, Alexander G., Ayturk, Ugur M., Baht, Gurpreet S.
Publicado 2022

Loss of HIF-1α in the Notochord Results in Cell Death and Complete Disappearance of the Nucleus Pulposus

por Merceron, Christophe, Mangiavini, Laura, Robling, Alexander, Wilson, Tremika LeShan, Giaccia, Amato J., Shapiro, Irving M., Schipani, Ernestina, Risbud, Makarand V.
Publicado 2014

Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo

por Bullock, Whitney A., Hoggatt, April M., Horan, Daniel J., Elmendorf, Andrew J., Sato, Amy Y., Bellido, Teresita, Loots, Gabriela G., Pavalko, Fredrick M., Robling, Alexander G.
Publicado 2019

The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects

por Bird, Ian M., Kim, Susie H., Schweppe, Devin K., Caetano-Lopes, Joana, Robling, Alexander G., Charles, Julia F., Gygi, Steven P., Warman, Matthew L., Smits, Patrick J.
Publicado 2018

Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice

por Donham, Cristine, Chicana, Betsabel, Robling, Alexander G., Mohamed, Asmaa, Elizaldi, Sonny, Chi, Michael, Freeman, Brian, Millan, Alberto, Murugesh, Deepa K., Hum, Nicholas R., Sebastian, Aimy, Loots, Gabriela G., Manilay, Jennifer O.
Publicado 2021

Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

por Diegel, Cassandra R., Hann, Steven, Ayturk, Ugur M., Hu, Jennifer C. W., Lim, Kyung-Eun, Droscha, Casey J., Madaj, Zachary B., Foxa, Gabrielle E., Izaguirre, Isaac, Robling, Alexander G., Warman, Matthew L., Williams, Bart O.
Publicado 2020