Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20

por De Miranda, Briana R., Rocha, Emily M., Castro, Sandra L., Greenamyre, J. Timothy
Publicado 2020

Progressive decline of glucocerebrosidase in aging and Parkinson's disease

por Rocha, Emily M, Smith, Gaynor A, Park, Eric, Cao, Hongmei, Brown, Eilish, Hallett, Penelope, Isacson, Ole
Publicado 2015

Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain

por Hallett, Penelope J., Huebecker, Mylene, Brekk, Oeystein R., Moloney, Elizabeth B., Rocha, Emily M., Priestman, David A., Platt, Frances M., Isacson, Ole
Publicado 2018

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

por Smith, Gaynor A., Rocha, Emily M., Rooney, Thomas, Barneoud, Pascal, McLean, Jesse R., Beagan, Jonathan, Osborn, Teresia, Coimbra, Madeleine, Luo, Yongyi, Hallett, Penelope J., Isacson, Ole
Publicado 2015

Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy

por Van Laar, Amber D., Webb, Katherine R., Keeney, Matthew T., Van Laar, Victor S., Zharikov, Alevtina, Burton, Edward A., Hastings, Teresa G., Glajch, Kelly E., Hirst, Warren D., Greenamyre, J. Timothy, Rocha, Emily M.
Publicado 2023

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson’s disease

por Rocha, Emily M., De Miranda, Briana R., Castro, Sandra, Drolet, Robert, Hatcher, Nathan G., Yao, Lihang, Smith, Sean M., Keeney, Matthew T., Di Maio, Roberto, Kofler, Julia, Hastings, Teresa G., Greenamyre, J. Timothy
Publicado 2019

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

por Rocha, Emily M., Smith, Gaynor A., Park, Eric, Cao, Hongmei, Graham, Anne-Renee, Brown, Eilish, McLean, Jesse R., Hayes, Melissa A., Beagan, Jonathan, Izen, Sarah C., Perez-Torres, Eduardo, Hallett, Penelope J., Isacson, Ole
Publicado 2015