Editorial: Human organoid technology for virus research

por Pajkrt, Dasja, Krenn, Veronica, Rocha-Pereira, Joana
Publicado 2023

Norovirus: Targets and tools in antiviral drug discovery

por Rocha-Pereira, Joana, Neyts, Johan, Jochmans, Dirk
Publicado 2014

Assessment of the anti-norovirus activity in cell culture using the mouse norovirus: Identification of active compounds

por Van Dycke, Jana, Rymenants, Jasper, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

Screening and in vitro antiviral assessment of small molecules against fluorescent protein-expressing Bunyamwera virus in a cell-based assay using high-content imaging

por ter Horst, Sebastiaan, Chiu, Winston, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

Assessment of the anti-norovirus activity in cell culture using the mouse norovirus: Early mechanistic studies

por Dycke, Jana Van, Rymenants, Jasper, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

Current and Future Antiviral Strategies to Tackle Gastrointestinal Viral Infections

por Santos-Ferreira, Nanci, Van Dycke, Jana, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

Targeting the Viral Polymerase of Diarrhea-Causing Viruses as a Strategy to Develop a Single Broad-Spectrum Antiviral Therapy

por Bassetto, Marcella, Van Dycke, Jana, Neyts, Johan, Brancale, Andrea, Rocha-Pereira, Joana
Publicado 2019

Synthesis and in vitro antiviral evaluation of 4-substituted 3,4-dihydropyrimidinones

por Kumarasamy, Dhanabal, Roy, Biswajit Gopal, Rocha-Pereira, Joana, Neyts, Johan, Nanjappan, Satheeshkumar, Maity, Subhasis, Mookerjee, Musfiqua, Naesens, Lieve
Publicado 2017

The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae

por Cuvry, Arno, Gozalbo-Rovira, Roberto, Strubbe, Dufie, Neyts, Johan, de Witte, Peter, Rodríguez-Díaz, Jésus, Rocha-Pereira, Joana
Publicado 2022

A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase

por Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T., Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella
Publicado 2019

Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ

por Jacobs, Sophie, Wavreil, Fanny, Schepens, Bert, Gad, Hans Henrik, Hartmann, Rune, Rocha-Pereira, Joana, Neyts, Johan, Saelens, Xavier, Michiels, Thomas
Publicado 2018

Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery

por Masmoudi, Fatma, Santos-Ferreira, Nanci, Pajkrt, Dasja, Wolthers, Katja C., DeGroot, Jeroen, Vlaming, Maria L. H., Rocha-Pereira, Joana, Buti, Ludovico
Publicado 2023

Ex vivo gut cultures of Aedes aegypti are efficiently infected by mosquito-borne alpha- and flaviviruses

por Rosales Rosas, Ana Lucia, Wang, Lanjiao, Goossens, Sara, Cuvry, Arno, Li, Li-Hsin, Santos-Ferreira, Nanci, Soto, Alina, Dallmeier, Kai, Rocha-Pereira, Joana, Delang, Leen
Publicado 2023

Molecular Chaperone Hsp90 Is a Therapeutic Target for Noroviruses

por Vashist, Surender, Urena, Luis, Gonzalez-Hernandez, Mariam B., Choi, Jayoung, de Rougemont, Alexis, Rocha-Pereira, Joana, Neyts, Johan, Hwang, Seungmin, Wobus, Christiane E., Goodfellow, Ian
Publicado 2015

Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance

por Van Dycke, Jana, Puxeddu, Michela, La Regina, Giuseppe, Mastrangelo, Eloise, Tarantino, Delia, Rymenants, Jasper, Sebastiani, Jessica, Nalli, Marianna, Matthijnssens, Jelle, Neyts, Johan, Silvestri, Romano, Rocha-Pereira, Joana
Publicado 2021

A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo

por Van Dycke, Jana, Dai, Wenhao, Stylianidou, Zoe, Li, Jian, Cuvry, Arno, Roux, Emma, Li, Bingqian, Rymenants, Jasper, Bervoets, Lindsey, de Witte, Peter, Liu, Hong, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

A robust human norovirus replication model in zebrafish larvae

por Van Dycke, Jana, Ny, Annelii, Conceição-Neto, Nádia, Maes, Jan, Hosmillo, Myra, Cuvry, Arno, Goodfellow, Ian, Nogueira, Tatiane C., Verbeken, Erik, Matthijnssens, Jelle, de Witte, Peter, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2019

Structure–Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections

por Ferla, Salvatore, Varricchio, Carmine, Knight, William, Ho, Pui Kei, Saporito, Fabiana, Tropea, Beatrice, Fagan, Giulio, Flude, Ben Matthew, Bevilacqua, Federica, Santos-Ferreira, Nanci, Van Dycke, Jana, Neyts, Johan, Brancale, Andrea, Rocha-Pereira, Joana, Bassetto, Marcella
Publicado 2021

Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase

por Giancotti, Gilda, Nannetti, Giulio, Padalino, Gilda, Landini, Martina, Santos-Ferreira, Nanci, Van Dycke, Jana, Naccarato, Valentina, Patel, Usheer, Silvestri, Romano, Neyts, Johan, Gozalbo-Rovira, Roberto, Rodríguez-Díaz, Jésus, Rocha-Pereira, Joana, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella
Publicado 2022

HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

por Foo, Caroline S., Abdelnabi, Rana, Kaptein, Suzanne J.F., Zhang, Xin, ter Horst, Sebastiaan, Mols, Raf, Delang, Leen, Rocha-Pereira, Joana, Coelmont, Lotte, Leyssen, Pieter, Dallmeier, Kai, Vergote, Valentijn, Heylen, Elisabeth, Vangeel, Laura, Chatterjee, Arnab K., Annaert, Pieter P., Augustijns, Patrick F., De Jonghe, Steven, Jochmans, Dirk, Gouwy, Mieke, Cambier, Seppe, Vandooren, Jennifer, Proost, Paul, van Laer, Christine, Weynand, Birgit, Neyts, Johan
Publicado 2022