Inducing neuronal regeneration and differentiation via the BDNF/TrkB signaling pathway: a key target against neurodegenerative diseases?

por Antonijevic, Mirjana, Dallemagne, Patrick, Rochais, Christophe
Publicado 2023

C3-Symmetric Ligands in Drug Design: When the Target Controls the Aesthetics of the Drug

por Antonijevic, Mirjana, Rochais, Christophe, Dallemagne, Patrick
Publicado 2023

Conceptual Framework of the Design of Pleiotropic Drugs against Alzheimer’s Disease

por Guiselin, Thomas, Lecoutey, Cédric, Rochais, Christophe, Dallemagne, Patrick
Publicado 2023

26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de Pharmacochimie

por Dallemagne, Patrick, Rochais, Christophe, Marchand, Pascal, Besson, Thierry
Publicado 2019

Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer’s Disease Treatment through Rigidification Strategy

por Lecoutey, Cédric, Legay, Rémi, Davis, Audrey, Sopková-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe
Publicado 2021

A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT(4)R) Agonist and Serotonergic S...

por Hatat, Bérénice, Yahiaoui, Samir, Lecoutey, Cédric, Davis, Audrey, Freret, Thomas, Boulouard, Michel, Claeysen, Sylvie, Rochais, Christophe, Dallemagne, Patrick
Publicado 2019

A chemical screen identifies two novel small compounds that alter Arabidopsis thaliana pollen tube growth

por Laggoun, Ferdousse, Dardelle, Flavien, Dehors, Jérémy, Falconet, Denis, Driouich, Azeddine, Rochais, Christophe, Dallemagne, Patrick, Lehner, Arnaud, Mollet, Jean-Claude
Publicado 2019

Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT(4) receptors activities for the treatment of Alzheimer’s disease

por Lalut, Julien, Payan, Hugo, Davis, Audrey, Lecoutey, Cédric, Legay, Rémi, Sopkova-de Oliveira Santos, Jana, Claeysen, Sylvie, Dallemagne, Patrick, Rochais, Christophe
Publicado 2020

First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer’s Disease

por Guieu, Benjamin, Lecoutey, Cedric, Legay, Rémi, Davis, Audrey, Sopkova de Oliveira Santos, Jana, Altomare, Cosimo Damiano, Catto, Marco, Rochais, Christophe, Dallemagne, Patrick
Publicado 2020

Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer’s Disease Treatment

por Adnet, Thomas, Groo, Anne-Claire, Picard, Céline, Davis, Audrey, Corvaisier, Sophie, Since, Marc, Bounoure, Frédéric, Rochais, Christophe, Le Pluart, Loïc, Dallemagne, Patrick, Malzert-Fréon, Aurélie
Publicado 2020

29th Annual GP2A Medicinal Chemistry Conference

por Helesbeux, Jean-Jacques, Carro, Laura, McCarthy, Florence O., Moreira, Vânia M., Giuntini, Francesca, O’Boyle, Niamh, Matthews, Susan E., Bayraktar, Gülşah, Bertrand, Samuel, Rochais, Christophe, Marchand, Pascal
Publicado 2021

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca(2+) Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

por Malek, Rim, Simakov, Alexey, Davis, Audrey, Maj, Maciej, Bernard, Paul J., Wnorowski, Artur, Martin, Helene, Marco-Contelles, José, Chabchoub, Fakher, Dallemagne, Patrick, Rochais, Christophe, Jozwiak, Krzysztof, Ismaili, Lhassane
Publicado 2022

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease

por Toublet, François-Xavier, Lecoutey, Cédric, Lalut, Julien, Hatat, Bérénice, Davis, Audrey, Since, Marc, Corvaisier, Sophie, Freret, Thomas, Sopkova de Oliveira Santos, Jana, Claeysen, Sylvie, Boulouard, Michel, Dallemagne, Patrick, Rochais, Christophe
Publicado 2019