Vitamin D and Its Receptor from a Structural Perspective

por Rochel, Natacha
Publicado 2022

Solution Structures of PPARγ2/RXRα Complexes

por Osz, Judit, Pethoukhov, Maxim V., Sirigu, Serena, Svergun, Dmitri I., Moras, Dino, Rochel, Natacha
Publicado 2012

Phosphorylation of the Retinoic Acid Receptor Alpha Induces a Mechanical Allosteric Regulation and Changes in Internal Dynamics

por Chebaro, Yassmine, Amal, Ismail, Rochel, Natacha, Rochette-Egly, Cécile, Stote, Roland H., Dejaegere, Annick
Publicado 2013

Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer

por Belorusova, Anna Y, Bourguet, Maxime, Hessmann, Steve, Chalhoub, Sandra, Kieffer, Bruno, Cianférani, Sarah, Rochel, Natacha
Publicado 2020

Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ

por Chebaro, Yassmine, Sirigu, Serena, Amal, Ismail, Lutzing, Régis, Stote, Roland H., Rochette-Egly, Cécile, Rochel, Natacha, Dejaegere, Annick
Publicado 2017

Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor

por Osz, Judit, McEwen, Alastair G., Poussin-Courmontagne, Pierre, Moutier, Emmanuel, Birck, Catherine, Davidson, Irwin, Moras, Dino, Rochel, Natacha
Publicado 2015

Carborane-based design of a potent vitamin D receptor agonist

por Otero, Rocio, Seoane, Samuel, Sigüeiro, Rita, Belorusova, Anna Y., Maestro, Miguel A., Pérez-Fernández, Roman, Rochel, Natacha, Mouriño, Antonio
Publicado 2016

Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1

por Hassan, Sarah, Peluso, Jean, Chalhoub, Sandra, Idoux Gillet, Ysia, Benkirane-Jessel, Nadia, Rochel, Natacha, Fuhrmann, Guy, Ubeaud-Sequier, Genevieve
Publicado 2020

Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants

por Belorusova, Anna Y., Rovito, Daniela, Chebaro, Yassmine, Doms, Stefanie, Verlinden, Lieve, Verstuyf, Annemieke, Metzger, Daniel, Rochel, Natacha, Laverny, Gilles
Publicado 2022

Design, Synthesis, Evaluation and Structure of Allenic 1α,25‐Dihydroxyvitamin D(3) Analogs with Locked Mobility at C‐17

por Fraga, Ramón, Len, Kateryna, Lutzing, Regis, Laverny, Gilles, Loureiro, Julian, Maestro, Miguel A., Rochel, Natacha, Rodriguez‐Borges, Enrique, Mouriño, Antonio
Publicado 2021

1α,25(OH)(2)-3-Epi-Vitamin D(3), a Natural Physiological Metabolite of Vitamin D(3): Its Synthesis, Biological Activity and Crystal Structure with Its Receptor

por Molnár, Ferdinand, Sigüeiro, Rita, Sato, Yoshiteru, Araujo, Clarisse, Schuster, Inge, Antony, Pierre, Peluso, Jean, Muller, Christian, Mouriño, Antonio, Moras, Dino, Rochel, Natacha
Publicado 2011

Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

por Rovito, Daniela, Belorusova, Anna Y., Chalhoub, Sandra, Rerra, Anna-Isavella, Guiot, Elvire, Molin, Arnaud, Linglart, Agnès, Rochel, Natacha, Laverny, Gilles, Metzger, Daniel
Publicado 2020

HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

por Kolesnikova, Olga, Zachayus, Amélie, Pichard, Simon, Osz, Judit, Rochel, Natacha, Rossolillo, Paola, Kolb-Cheynel, Isabelle, Troffer-Charlier, Nathalie, Compe, Emmanuel, Bensaude, Olivier, Berger, Imre, Poterszman, Arnaud
Publicado 2022

Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

por Kolesnikova, Olga, Zachayus, Amélie, Pichard, Simon, Osz, Judit, Rochel, Natacha, Rossolillo, Paola, Kolb-Cheynel, Isabelle, Troffer-Charlier, Nathalie, Compe, Emmanuel, Bensaude, Olivier, Berger, Imre, Poterszman, Arnaud
Publicado 2022

Conformational editing of intrinsically disordered protein by α-methylation

por Bauer, Valentin, Schmidtgall, Boris, Gógl, Gergő, Dolenc, Jozica, Osz, Judit, Nominé, Yves, Kostmann, Camille, Cousido-Siah, Alexandra, Mitschler, André, Rochel, Natacha, Travé, Gilles, Kieffer, Bruno, Torbeev, Vladimir
Publicado 2020

The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

por Sato, Yoshiteru, Ramalanjaona, Nick, Huet, Tiphaine, Potier, Noelle, Osz, Judit, Antony, Pierre, Peluso-Iltis, Carole, Poussin-Courmontagne, Pierre, Ennifar, Eric, Mély, Yves, Dejaegere, Annick, Moras, Dino, Rochel, Natacha
Publicado 2010

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

por Rühl, Ralph, Krzyżosiak, Agnieszka, Niewiadomska-Cimicka, Anna, Rochel, Natacha, Szeles, Lajos, Vaz, Belén, Wietrzych-Schindler, Marta, Álvarez, Susana, Szklenar, Monika, Nagy, Laszlo, de Lera, Angel R., Krężel, Wojciech
Publicado 2015

Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR–RXR

por Osz, Judit, McEwen, Alastair G, Bourguet, Maxime, Przybilla, Frédéric, Peluso-Iltis, Carole, Poussin-Courmontagne, Pierre, Mély, Yves, Cianférani, Sarah, Jeffries, Cy M, Svergun, Dmitri I, Rochel, Natacha
Publicado 2020

Investigation of 20S-hydroxyvitamin D(3) analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities

por Lin, Zongtao, Marepally, Srinivasa R., Goh, Emily S. Y., Cheng, Chloe Y. S., Janjetovic, Zorica, Kim, Tae-Kang, Miller, Duane D., Postlethwaite, Arnold E., Slominski, Andrzej T., Tuckey, Robert C., Peluso-Iltis, Carole, Rochel, Natacha, Li, Wei
Publicado 2018

1α,20S-Dihydroxyvitamin D(3) Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis

por Lin, Zongtao, Chen, Hao, Belorusova, Anna Y., Bollinger, John C., Tang, Edith K. Y., Janjetovic, Zorica, Kim, Tae-Kang, Wu, Zhongzhi, Miller, Duane D., Slominski, Andrzej T., Postlethwaite, Arnold E., Tuckey, Robert C., Rochel, Natacha, Li, Wei
Publicado 2017