Therapeutic Targets in Chlamydial Fatty Acid and Phospholipid Synthesis

por Yao, Jiangwei, Rock, Charles O.
Publicado 2018

A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus

por Whaley, Sarah G., Frank, Matthew W., Rock, Charles O.
Publicado 2023

Branched-chain amino acid metabolism controls membrane phospholipid structure in Staphylococcus aureus

por Frank, Matthew W., Whaley, Sarah G., Rock, Charles O.
Publicado 2021

Pantothenate Kinase 1 Is Required to Support the Metabolic Transition from the Fed to the Fasted State

por Leonardi, Roberta, Rehg, Jerold E., Rock, Charles O., Jackowski, Suzanne
Publicado 2010

The Phospholipase A1 Activity of Glycerol Ester Hydrolase (Geh) Is Responsible for Extracellular 2-12(S)-Methyltetradecanoyl-Lysophosphatidylglycerol Production in Staphylococcus a...

por Subramanian, Chitra, Frank, Matthew W., Yun, My-Kyung, Rock, Charles O.
Publicado 2023

Lysophosphatidylglycerol (LPG) phospholipase D maintains membrane homeostasis in Staphylococcus aureus by converting LPG to lysophosphatidic acid

por Subramanian, Chitra, Yun, Mi-Kyung, Frank, Matthew M., Rock, Charles O.
Publicado 2023

Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in Staphylococcus aureus

por Ericson, Megan E., Subramanian, Chitra, Frank, Matthew W., Rock, Charles O.
Publicado 2017

Phosphatidylglycerol homeostasis in glycerol-phosphate auxotrophs of Staphylococcus aureus

por Parsons, Joshua B, Yao, Jiangwei, Jackson, Pamela, Frank, Matthew, Rock, Charles O
Publicado 2013

Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii

por Radka, Christopher D., Miller, Darcie J., Frank, Matthew W., Rock, Charles O.
Publicado 2022

Disruption of Glycolysis by Nutritional Immunity Activates a Two-Component System That Coordinates a Metabolic and Antihost Response by Staphylococcus aureus

por Párraga Solórzano, Paola K., Yao, Jiangwei, Rock, Charles O., Kehl-Fie, Thomas E.
Publicado 2019

Structural Basis for the Transcriptional Regulation of Membrane Lipid Homeostasis

por Miller, Darcie J., Zhang, Yong-Mei, Subramanian, Chitra, Rock, Charles O., White, Stephen W.
Publicado 2010

Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria

por Whaley, Sarah G., Radka, Christopher D., Subramanian, Chitra, Frank, Matthew W., Rock, Charles O.
Publicado 2021

Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase

por Subramanian, Chitra, Cuypers, Maxime G., Radka, Christopher D., White, Stephen W., Rock, Charles O.
Publicado 2022

Structure and mechanism of Staphylococcus aureus oleate hydratase (OhyA)

por Radka, Christopher D., Batte, Justin L., Frank, Matthew W., Young, Brandon M., Rock, Charles O.
Publicado 2021

Oleate Hydratase (OhyA) Is a Virulence Determinant in Staphylococcus aureus

por Radka, Christopher D., Batte, Justin L., Frank, Matthew W., Rosch, Jason W., Rock, Charles O.
Publicado 2021

Competence-Associated Peptide BriC Alters Fatty Acid Biosynthesis in Streptococcus pneumoniae

por Aggarwal, Surya D., Gullett, Jessica M., Fedder, Tara, Safi, J. Pedro F., Rock, Charles O., Hiller, N. Luisa
Publicado 2021

Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site

por Frank, Matthew W., Yao, Jiangwei, Batte, Justin L., Gullett, Jessica M., Subramanian, Chitra, Rosch, Jason W., Rock, Charles O.
Publicado 2020

Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae

por Echlin, Haley, Frank, Matthew W., Iverson, Amy, Chang, Ti-Cheng, Johnson, Michael D. L., Rock, Charles O., Rosch, Jason W.
Publicado 2016

Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia

por Subramanian, Chitra, Frank, Matthew W., Tangallapally, Rajendra, Yun, Mi‐Kyung, White, Stephen W., Lee, Richard E., Rock, Charles O., Jackowski, Suzanne
Publicado 2022

LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators

por Sharma, Lalit Kumar, Yun, Mi Kyung, Subramanian, Chitra, Tangallapally, Rajendra, Jackowski, Suzanne, Rock, Charles O., White, Stephen W., Lee, Richard E.
Publicado 2021