Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target

por Long, Thavy, Rojo-Arreola, Liliana, Shi, Da, El-Sakkary, Nelly, Jarnagin, Kurt, Rock, Fernando, Meewan, Maliwan, Rascón, Alberto A., Lin, Lin, Cunningham, Katherine A., Lemieux, George A., Podust, Larissa, Abagyan, Ruben, Ashrafi, Kaveh, McKerrow, James H., Caffrey, Conor R.
Publicado 2017

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs

por Carter, David S., Jacobs, Robert T., Freund, Yvonne R., Berry, Pamela W., Akama, Tsutomu, Easom, Eric E., Lunde, Christopher S., Rock, Fernando, Stefanakis, Rianna, McKerrow, James, Fischer, Chelsea, Bulman, Christina A., Lim, Kee Chong, Suzuki, Brian M., Tricoche, Nancy, Sakanari, Judy A., Lustigman, Sara, Plattner, Jacob J.
Publicado 2019

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs

por Akama, Tsutomu, Freund, Yvonne R., Berry, Pamela W., Carter, David S., Easom, Eric E., Jarnagin, Kurt, Lunde, Christopher S., Plattner, Jacob J., Rock, Fernando, Stefanakis, Rianna, Fischer, Chelsea, Bulman, Christina A., Lim, Kee Chong, Suzuki, Brian M., Tricoche, Nancy, Mansour, Abdelmoneim, DiCosty, Utami, McCall, Scott, Carson, Ben, McCall, John W., McKerrow, James, Hübner, Marc P., Specht, Sabine, Hoerauf, Achim, Lustigman, Sara, Sakanari, Judy A., Jacobs, Robert T.
Publicado 2019

Dual inhibition of α(v)β(6) and α(v)β(1) reduces fibrogenesis in lung tissue explants from patients with IPF

por Decaris, Martin L., Schaub, Johanna R., Chen, Chun, Cha, Jacob, Lee, Gail G., Rexhepaj, Megi, Ho, Steve S., Rao, Vikram, Marlow, Megan M., Kotak, Prerna, Budi, Erine H., Hooi, Lisa, Wu, Jianfeng, Fridlib, Marina, Martin, Shamra P., Huang, Shaoyi, Chen, Ming, Muñoz, Manuel, Hom, Timothy F., Wolters, Paul J., Desai, Tushar J., Rock, Fernando, Leftheris, Katerina, Morgans, David J., Lepist, Eve-Irene, Andre, Patrick, Lefebvre, Eric A., Turner, Scott M.
Publicado 2021

Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

por Jacobs, Robert T., Lunde, Christopher S., Freund, Yvonne R., Hernandez, Vincent, Li, Xianfeng, Xia, Yi, Carter, David S., Berry, Pamela W., Halladay, Jason, Rock, Fernando, Stefanakis, Rianna, Easom, Eric, Plattner, Jacob J., Ford, Louise, Johnston, Kelly L., Cook, Darren A. N., Clare, Rachel, Cassidy, Andrew, Myhill, Laura, Tyrer, Hayley, Gamble, Joanne, Guimaraes, Ana F., Steven, Andrew, Lenz, Franziska, Ehrens, Alexandra, Frohberger, Stefan J., Koschel, Marianne, Hoerauf, Achim, Hübner, Marc P., McNamara, Case W., Bakowski, Malina A., Turner, Joseph D., Taylor, Mark J., Ward, Stephen A.
Publicado 2019

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

por Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z., Easom, Eric E., Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L., Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G., Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J., O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B., Waters, M. Gerard, Ma, Zhenkun, Ioerger, Thomas R., Sacchettini, James C., Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J., Alley, M. R. K.
Publicado 2016