Viewing AML through a New Lens: Technological Advances in the Study of Epigenetic Regulation

por Godfrey, Laura C., Rodriguez-Meira, Alba
Publicado 2022

TARGET-Seq: A Protocol for High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

por Rodriguez-Meira, Alba, O’Sullivan, Jennifer, Rahman, Haseeb, Mead, Adam J.
Publicado 2020

OR34-2 SREBP1 Drives KRT80-Dependent Cytoskeletal Changes and Invasive Behaviour in Endocrine-Resistant ERα Breast Cancer

por Perone, Ylenia, Rodríguez Meira, Alba, Farruggia, Aaron, Győrffy, Balázs, Ion, Charlotte, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Publicado 2019

Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis

por Sousos, Nikolaos, Buck, Gemma, Rodriguez-Meira, Alba, Norfo, Ruggiero, Hamblin, Angela, Pezzella, Francesco, Davies, Jennifer, Hublitz, Philip, Psaila, Bethan, Mead, Adam J.
Publicado 2020

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

por Neo, Wen Hao, Meng, Yiran, Rodriguez-Meira, Alba, Fadlullah, Muhammad Z. H., Booth, Christopher A. G., Azzoni, Emanuele, Thongjuea, Supat, de Bruijn, Marella F. T. R., Jacobsen, Sten Eirik W., Mead, Adam J., Lacaud, Georges
Publicado 2021

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

por Rodriguez-Meira, Alba, Buck, Gemma, Clark, Sally-Ann, Povinelli, Benjamin J., Alcolea, Veronica, Louka, Eleni, McGowan, Simon, Hamblin, Angela, Sousos, Nikolaos, Barkas, Nikolaos, Giustacchini, Alice, Psaila, Bethan, Jacobsen, Sten Eirik W., Thongjuea, Supat, Mead, Adam J.
Publicado 2019

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

por Di Genua, Cristina, Valletta, Simona, Buono, Mario, Stoilova, Bilyana, Sweeney, Connor, Rodriguez-Meira, Alba, Grover, Amit, Drissen, Roy, Meng, Yiran, Beveridge, Ryan, Aboukhalil, Zahra, Karamitros, Dimitris, Belderbos, Mirjam E., Bystrykh, Leonid, Thongjuea, Supat, Vyas, Paresh, Nerlov, Claus
Publicado 2020

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation

por Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A.G., Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M., Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J.
Publicado 2019

SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

por Perone, Ylenia, Farrugia, Aaron J., Rodríguez-Meira, Alba, Győrffy, Balázs, Ion, Charlotte, Uggetti, Andrea, Chronopoulos, Antonios, Marrazzo, Pasquale, Faronato, Monica, Shousha, Sami, Davies, Claire, Steel, Jennifer H., Patel, Naina, del Rio Hernandez, Armando, Coombes, Charles, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Publicado 2019

Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

por Nguyen, Van T. M., Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Rodriguez-Meira, Alba, Patten, Darren K., Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R. Charles, Magnani, Luca
Publicado 2019

Author Correction: SREBP1 drives keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

por Perone, Ylenia, Farrugia, Aaron J., Rodríguez-Meira, Alba, Győrffy, Balázs, Ion, Charlotte, Uggetti, Andrea, Chronopoulos, Antonios, Marrazzo, Pasquale, Faronato, Monica, Shousha, Sami, Davies, Claire, Steel, Jennifer H., Patel, Naina, del Rio Hernandez, Armando, Coombes, Charles, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Publicado 2019

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

por Psaila, Bethan, Wang, Guanlin, Rodriguez-Meira, Alba, Li, Rong, Heuston, Elisabeth F., Murphy, Lauren, Yee, Daniel, Hitchcock, Ian S., Sousos, Nikolaos, O’Sullivan, Jennifer, Anderson, Stacie, Senis, Yotis A., Weinberg, Olga K., Calicchio, Monica L., Iskander, Deena, Royston, Daniel, Milojkovic, Dragana, Roberts, Irene, Bodine, David M., Thongjuea, Supat, Mead, Adam J.
Publicado 2020

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

por Luis, Tiago C., Barkas, Nikolaos, Carrelha, Joana, Giustacchini, Alice, Mazzi, Stefania, Norfo, Ruggiero, Wu, Bishan, Aliouat, Affaf, Guerrero, Jose A., Rodriguez-Meira, Alba, Bouriez-Jones, Tiphaine, Macaulay, Iain C., Jasztal, Maria, Zhu, Guangheng, Ni, Heyu, Robson, Matthew J., Blakely, Randy D., Mead, Adam J., Nerlov, Claus, Ghevaert, Cedric, Jacobsen, Sten Eirik W.
Publicado 2023

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

por Louka, Eleni, Povinelli, Benjamin, Rodriguez-Meira, Alba, Buck, Gemma, Wen, Wei Xiong, Wang, Guanlin, Sousos, Nikolaos, Ashley, Neil, Hamblin, Angela, Booth, Christopher A.G., Roy, Anindita, Elliott, Natalina, Iskander, Deena, de la Fuente, Josu, Fordham, Nicholas, O’Byrne, Sorcha, Inglott, Sarah, Norfo, Ruggiero, Salio, Mariolina, Thongjuea, Supat, Rao, Anupama, Roberts, Irene, Mead, Adam J.
Publicado 2021

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

por Schnegg-Kaufmann, Annatina S., Thoms, Julie A. I., Bhuyan, Golam Sarower, Hampton, Henry R., Vaughan, Lachlin, Rutherford, Kayleigh, Kakadia, Purvi M., Lee, Hui Mei, Johansson, Emma M. V., Failes, Timothy W., Arndt, Greg M., Koval, Jason, Lindeman, Robert, Warburton, Pauline, Rodriguez-Meira, Alba, Mead, Adam J., Unnikrishnan, Ashwin, Davidson, Sarah, Polizzotto, Mark N., Hertzberg, Mark, Papaemmanuil, Elli, Bohlander, Stefan K., Faridani, Omid R., Jolly, Christopher J., Zanini, Fabio, Pimanda, John E.
Publicado 2023

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

por Rodriguez-Meira, Alba, Norfo, Ruggiero, Wen, Sean, Chédeville, Agathe L., Rahman, Haseeb, O’Sullivan, Jennifer, Wang, Guanlin, Louka, Eleni, Kretzschmar, Warren W., Paterson, Aimee, Brierley, Charlotte, Martin, Jean-Edouard, Demeule, Caroline, Bashton, Matthew, Sousos, Nikolaos, Moralli, Daniela, Subha Meem, Lamia, Carrelha, Joana, Wu, Bishan, Hamblin, Angela, Guermouche, Helene, Pasquier, Florence, Marzac, Christophe, Girodon, François, Vainchenker, William, Drummond, Mark, Harrison, Claire, Chapman, J. Ross, Plo, Isabelle, Jacobsen, Sten Eirik W., Psaila, Bethan, Thongjuea, Supat, Antony-Debré, Iléana, Mead, Adam J.
Publicado 2023

Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis

por Fang, Zijian, Corbizi Fattori, Giuditta, McKerrell, Thomas, Boucher, Rebecca H., Jackson, Aimee, Fletcher, Rachel S., Forte, Dorian, Martin, Jose-Ezequiel, Fox, Sonia, Roberts, James, Glover, Rachel, Harris, Erica, Bridges, Hannah R., Grassi, Luigi, Rodriguez-Meira, Alba, Mead, Adam J., Knapper, Steven, Ewing, Joanne, Butt, Nauman M., Jain, Manish, Francis, Sebastian, Clark, Fiona J., Coppell, Jason, McMullin, Mary F., Wadelin, Frances, Narayanan, Srinivasan, Milojkovic, Dragana, Drummond, Mark W., Sekhar, Mallika, ElDaly, Hesham, Hirst, Judy, Paramor, Maike, Baxter, E. Joanna, Godfrey, Anna L., Harrison, Claire N., Méndez-Ferrer, Simón
Publicado 2023